...Pathopharmacological Foundations for Advanced Nursing Practice Student name Institution Pathopharmacological Foundations for Advanced Nursing Practice A. Investigated Disease Process: The paper investigates the processes of Alzheimer’s and pharmacological implication. A1. Pathophysiology: The theory based on monoamine-deficiency determines that the recognizable pathophysiological source of Alzheimer’s Disease is the occurrence of dementia and dementia like symptoms (Unützer, & Park, 2012). Donepezil is applicable in the pathophysiology and is commendable by the therapeutic efficacy of its control. There are various conventional discussions based on the categorization and basis of dementia. The concept made by Emil Kraepelin'sdetermines that is a formulation of a Sigmund and disease. On the other hand, Freud perceives Alzheimer’s disease is an expression of internalized loss and weakness (Unützer, & Park, 2012). Alzheimer’s disease may not be categorized as a homogeneous disease, but it is a sophisticated phenomenon that has various subtypes and at least one etiology. It also has various predispositions in symptomatology that range from mild to severe symptoms. A2. Standard of Practice: The American Psychiatric Association presents the best practices to be followed while addressing Alzheimer’s disease disorder. The practices aim to assist healthcare providers in making informed decisions by providing...
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...Pathopharmacological Foundations for Advanced Nursing Practice Competency Assessment WUT Task 1 Pamela L. Taylor RN-C(OB), BSN Western Governors University June 2016 A. Disease Process For the purpose of discussion of pathopharmacological features of a specific disease process, this paper will provide information related to heart disease in the form of coronary artery disease (CAD). A1. Pathophysiology Analysis Cardiovascular disease (CVD) is the number one cause of mortality worldwide and becoming a steadily more investigated problem due to its prevalence. Much research is going into genetic, inflammatory mechanisms and neuro-hormonal factors related to CVD as scientific knowledge evolves regarding complexity of this broad pathophysiology. Atherosclerosis is the leading cause of the subsection of CVD called CAD. This is a form of arteriosclerosis where there is progressive thickening and hardening of the vessel walls of the two major coronary arteries and their branches. The thickening is an accumulation of lipid-laden macrophages inside the wall of the artery leading to the formation of lesions and plaque buildup (McCance, K. & Huether, S., 2014). When the plaque develops on the coronary artery walls the pumping ability of the heart becomes impaired as oxygen and nutrients needed for heart function may be partially or completely impeded. Complete occlusion of a coronary artery or one of its branches leads to a myocardial...
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...Heart Failure Western Governors University Pathopharmacological Foundations for Advanced Nursing Practice Heart Failure It is estimated that about five million people in the United States are living with heart failure with an overwhelming number of 550,000 newly diagnosed cases each year, costing the nation roughly $32 billion dollars per year (Centers for Disease Control and Prevention, 2016). Heart failure is a complex, pathophysiological condition in which the ventricles of the heart is weakened and unable to pump effectively to meet the body’s needs for nutrients or has lost adequate filling capacity. Clinical presentations of heart failure depends on which ventricles have failed to pump blood adequately; left ventricular failure, also known as congestive heart failure (CHF) is more common than right ventricular failure (McCance & Huether, 2014). The most common symptoms of heart failure are shortness of breath, fatigue, and peripheral edema. HF is not a disease, but rather a manifestation of a diseased heart. Large number of disorders can lead to heart failure, and with the aging population and many surviving primary cardiac events, it is no surprise that the most common reason for hospitalization in patients older than 65 years old is heart failure (McClintock, Mose, & Smith, 2014). Heart failure has become a major public health problem because it is the only cardiac condition that continues to increase in prevalence (McClintock, Mose, & Smith, 2014)...
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