2-Ethylhexyl Trans-4-Methoxycinnate
Information Retrieval
Matthew Pratley
i) Molecular Structure Drawing:
Image 1: A molecular structure drawing of 2-Ethylhexyl Trans-4-Methoxycinnate as drawn on structure search on the Sigma Aldrich website (1) ii) Search:
Iupac Name:
2-Ethylhexyl Trans-4-methoxycinnate (2)
Other Names: Octinoxate (3), 4-methoxycinnimanic acid -2- ethylhexyl ester (3) (4) (5), OMC (3) (4) (5), Octyl Methoxycinnamate (3) (4) (5),
These other names are found throughout the five products that have the molecular structure as image 1 above.
The five products are:
Product 1:
2-Ethylhexyl Trans-4-methoxycinnamate 98%, Contains 500-1000ppm BHT as Stabiliser (2)
Purity: 98% (2)
Cost: £27 per 50ml (2)…show more content… The molecule is effective as a sunscreen and preventing damage to our skin due to the most damage to our skin is done by the high energy UV rays which can cause burns to the epidermis and can damage the DNA of a cell in the lower levels of the skin which can cause a cancer to form. In an experiment completed in 2000 the safety of this molecule as a sunscreen was questioned due to it being found to be toxic to dermal skin cells in mice in lower concentrations than were found in many commercial sunscreens (10). Although in more subsequent studies on both fully grown mice rather than cells and on humans it has been noted that the molecule cannot penetrate the skin enough to cause any significant damage to any dermal skin cells meaning that the mice in the original study must have had cuts or injuries that lead to the molecule poisoning the dermal layer of the skin (11).
References:
(1) -…show more content… 2015 (Accessed 28/10/15)
(6) - http://www.sigmaaldrich.com/catalog/product/usp/1477900?lang=en®ion=GB Published By: Sigma Aldrich Co. 2015 (Accessed 28/10/15)
(7) - http://www.sigmaaldrich.com/Graphics/COfAInfo/SigmaSAPQM/SPEC/43/437174/437174-BULK_______ALDRICH__.pdf Published By: Sigma Aldrich Co. 2015 (Accessed 28/10/15)
(8) - http://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/promo_NOT_INDEXED/General_Information/1/h_overview.pdf Published By: Sigma Aldrich Co. 2015 (Accessed 28/10/15)
(9) - http://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/promo_NOT_INDEXED/General_Information/1/p_overview.pdf Published By: Sigma Aldrich Co. 2015 (Accessed 28/10/15)
(10) - https://www.newscientist.com/article/mg16822591.900-sinister-side-of-sunscreens/ Published By: New Scientist (Accessed 02 /11/15)
(11) - https://www.ncbi.nlm.nih.gov/pubmed/15908756 Published by: Therapeutics Research Unit, University of Queensland, Southern Clinical School, University of Queensland, Princess Alexandra Hospital, Brisbane, Australia. (Accessed
