...European Medicines Agency Evaluation of Medicines for Human Use Doc.Ref:EMEA/501324/2008 ASSESSMENT REPORT FOR FILGRASTIM RATIOPHARM International Nonproprietary Name: filgrastim Procedure No. EMEA/H/C/824 Assessment Report as adopted by the CHMP with all information of a commercially confidential nature deleted. 7 Westferry Circus, Canary Wharf, London E14 4HB, UK Tel. (44-20) 74 18 84 00 Fax (44-20) 74 18 84 16 E-mail: mail@emea.europa.eu http://www.emea.europa.eu © European Medicines Agency, 2008. Reproduction is authorised provided the source is acknowledged. TABLE OF CONTENTS 1 BACKGROUND INFORMATION ON THE PROCEDURE................................................... 3 1.1 Submission of the dossier ...................................................................................................... 3 1.2 Steps taken for the assessment of the product........................................................................ 3 2 SCIENTIFIC DISCUSSION......................................................................................................... 5 2.1 Introduction............................................................................................................................ 5 2.2 Quality aspects ....................................................................................................................... 5 2.3 Non-clinical aspects ..................................................................................................
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...In 1932 the federal government commenced a medical study called The Tuskegee Study of Untreated Blacks with Syphilis in Macon County, Alabama. Four hundred and twelve men infected with the disease were selected for the study that faked long term treatment while really only giving placebos and liniments. The goal of this study was to determine if blacks reacted similar to the whites to the effects of the syphilis disease. After forty years it was discontinued and the Senate initiated an investigation of the study. At the time of the investigation, only one hundred and twenty-seven of the study’s original participants were still alive and had not died from the disease (Morehan, 2007). In the film, the story is told from the view point of Nurse Eunice Evers, one key character in the movie, who played the role of the real- life nurse who was a part of the Tuskegee Study. The movie, Miss Evers’ Boys portrays “the emotional effects of one of most amoral instances of governmental experimentation on humans ever perpetrated” (Morehan, 2007). It depicts the government’s involvement in research targeting a group of African American males, as it explores the depths of human tragedy and suffering that result from unethical act. The film also unveiled the racial tension that existed in America which did not only occur in the segregation of skin color but also founded upon disease (Morehan, 2007). The purpose of this paper is to analyze the film in order to critically examine bioethical issues...
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...Statistic- is a number computed from a sample of data. It is characteristic of a sample. A summary measure that is computed from a sample to describe a characteristic. (Numerical summary of the population) (Ex. The proportion of females randomly selected from the registered voters of a county or the average time it takes for the first 5 students to complete an exam) Parameter- A characteristic (numerical summary) of the entire population. A number computed from the entire population usually unobservable. Subject- the entities that we measure in a study. Population- the collection of all subjects under study. Proportion- of the observations that fall in a certain category is the frequency (count) of observations in that category divided by the total number of observations. Proportion and percentages (aka relative frequencies) Probability- the chance that an even will occur. Sample- a subset of the population. Random Samples are most valid. Design- Plan for how the data will be collected. Two events are dependent if the outcome or occurrence of the first affects the outcome or occurrence of the second so that the probability is changed. Sample Space- set of all possible outcomes for a random phenomenon Variables (COLUMNS)- characteristics or measurements on the subject. Event-subset of the sample space Description- summarizing the data that are obtained. Descriptive Statistics- methods for summarizing the data. Usually consists of bar graphs and...
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...Taji Bhinder English K101 Final Research Paper 12/17/13 Legalization of Marijuana Have you ever wondered if there is a natural medicine that can heal, help, and possibly cure people with irritable and deadly diseases? Well, there is a medicine; it’s an herb that is naturally grown from the Earth. Scientists have made discoveries leading back to 7,000 B.C.E. of this miscellaneous victor and its usage (Norml). The herb is called marijuana also known as pot, cannabis, weed, and God’s medicine in today’s society (Norml). Marijuana is a cannabinoid which is a chemical compound that naturally affects the immune and nervous system of humans and animals. It has been used for centuries as a natural therapeutic substance. This mysterious plant combats nausea, cancer, leukemia, and many other variants that still cannot be cured with prescription drugs. No one knows where this plant comes from, but findings of this plant’s DNA reach up to Northern China, thousands of years ago. For many decades this plant has been looked down upon. Media analysts and government officials in the United States give it a negative approach which allows the public to think negatively about it. Many people assume that weed is deadly because of what authority wants the public to believe, but what many do not know is the positive scientific evidence and facts that proves how effective it really is. The social policies regarding marijuana have changed throughout the years in the U.S. Although, several...
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...Chapter 1: Ethical Theory Meta-ethical positions include: * Ethical non-cognitivism (concept that ethics is a matter of feelings) * Ethical relativism (concept that ethics is relative to a particular point of view) * Ethical objectivism (notion that ethics is objective in nature). Meta-Ethical Positions Ethical Non-cognitivism The basis of ethical non-cognitivism is that ethical disagreement can be a highly emotional affair where no amount of reasoning is likely to convince the other party. * Example: “Let’s just agree to disagree” Ethical Relativism * Ethical relativism says that while ethical statements are cognitively meaningful, they do not hold in any objective sense because they depend on our point of view. * If we accept ethical relativism, then ethical disagreement among people who do not share the same perspective becomes impossible. * It assumes that if people agree on something, then it must be true. * Ethical relativism is suspect for a pragmatic reason: it is fundamentally at variance with our social practice. * Example: “To each his own”, or the belief that what’s right for one group isn’t necessarily right for another Ethical Objectivism * Ethical objectivism holds that right and wrong are objective phenomena. * Example: “I’m right and you’re wrong” What is Ethics? * As a discipline, ethics is a branch of philosophy. * It deals with questions of right and wrong conduct, and with what we ought to do and what...
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...USA $25.95 CANADA $27.95 • W h y do our headaches persist after taking a one-cent aspirin but disappear when we take a 50-cent aspirin? • Why does recalling the Ten Commandments reduce our tendency to lie, even when we couldn't possibly be caught? • W h y do we splurge on a lavish meal but cut coupons to save 25 cents on a can of soup? • W h y do we go back for second helpings at the unlimited buffet, even when our stomachs are already full? • And how did we ever start spending $4.15 on a cup of coffee when, just a few years ago, we used to pay less than a dollar? hen it comes to making decisions in our lives, we think we're in control. We think we're making smart, rational choices. But are we? In a series o f illuminating, often surprising experi ments, M I T behavioral economist Dan Ariely refutes the common assumption that we behave in fundamentally rational ways. Blending everyday experience with ground breaking research, Ariely explains how expectations, emotions, social norms, and other invisible, seemingly illogical forces skew our reasoning abilities. N o t only do we make astonishingly simple mistakes every day, but we make the same types of mistakes, Ariely discovers. We consistently overpay, underestimate, and procrastinate. We fail to understand the profound effects of our emotions on what we want, and we overvalue what we already own. Yet these misguided behaviors are neither random nor senseless. They're systematic and predict able—making us predictably irrational...
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...SAJ DEVSHI (C) AQA Psychology (A) Psya2 A* Students Model Essays The A* Students Handbook For More Psychology Resources visit: www.Loopa.co.uk C HAPTER 1 A little about me Firstly thank you for purchasing this book for AQA Psychology Psya2 (Paper 2). A bit about me: My name is Sajan Devshi and I was a private student that self-taught myself AQA Psychology from 2011-2012 and I received my certificate in January 2013 Achieving an A* Grade. The certificate you can view on my website http://www.loopa.co.uk - You can also get my other A* model essay answers from there too for the other topics I did. I achieved an A* grade overall scoring two A’s in Psya1 and Psya2 as well as 100% in both my A2 exams (Psya3 and Psya4) My final score was 373/400 ums points. (You only needed 90% in A2 and 320 for an A* grade). So basically I didn’t just beat the boundary - I absolutely smashed it. How did I do it? It wasn’t easy and I am by no means some savant genius. I made great notes and essays that simplified things for me as I had no teachers and it is these notes I share with you now for Psya2 and the essay questions that can be asked for it. If your curious to know more about me you can visit my website at http://www.loopa.co.uk There it tells you more about me, how I self-taught myself as well as contact me directly for help and advice as well as get my other essay answers there instantly. Theres also great resources there too with more added on a weekly basis...
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...北京新东方 GRE/GMAT 一对一课程，提分显著！咨询：010-62605555 美加研究生留学直通车 TOEFL/GRE/GMAT 冲分课程：http://bj.xdf.cn/publish/portal24/tab19365/ 请加“高智威”老师新浪微博 发邮件给高智威老师：zhiw.gao@gmail.com 咨询 GMAT/GRE 学习以及出国留学申请事宜 高智威 GRE 填空机经高频词汇 更新至 2013 年 2 月 序号 1 2 单词 preference progress 词 性 n. n. 所考含义 偏好 发展 释义 the act of preferring : the state of being preferred a forward or onward movement (as to an objective or to a goal) : ADVANCE of any of several light or medium grayish colors ranging in hue from yellow to orange simultaneous and contradictory attitudes or feelings (as attraction and repulsion) toward an object, person, or action JOYFUL: experiencing, causing, or showing joy : HAPPY showing or characterized by condescension : PATRONIZING to look on with scorn avoiding obvious emphasis or embellishment the period of one's greatest strength,vigor or prosperity in or into conflict with PLAY DOWN, DE-EMPHASIZE to refuse to take notice of to pay no attention to : treat as unworthy of regard or notice appropriate to one's mood, inclinations, or disposition a number greater than half of a total POPULAR：of or relating to the general public ABSOLUTE:of, relating to, or being an autocracy to undermine or destroy the force, value, or effectiveness of （inflation undercuts consumer buying power） removal or lightening of something oppressive, painful, or distressing being adverse often by reason of hostility or malevolence to make evident : EMPHASIZE, STRESS 3 lurid adj. 斑斓的 4 5 6 7 8 9 10...
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...e eBook Collection Scientific American-Psychology Appendix Ch01 This is a Protected PDF document. Please enter your user name and password to unlock the text. User Name: Password: Unlock Remember my user name and password. If you are experiencing problems unlocking this document or you have questions regarding Protectedpdf files please contact a Technical Support representative: In the United States: 1-877-832-4867 In Canada: 1-800-859-3682 Outside the U.S. and Canada: 1-602-387-2222 Email: technicalsupport@apollogrp.edu. molempien kuninkaasta pantiin rakenna suunnilleen valmiita kannatusta tunne vanhurskaus ranskan laupeutensa etko riitaa jutussa koyhaa huuto referenssit palvelijan seuduilla kuluu ainakin luulivat tuomari varmistaa vuoriston kansoihin poydan persian kommunismikerralla sinkut jokilaakson tekojaan uskovia kohtuullisen maara ostan kaytetty muidenkin hopeaa ylos eloon tavoin persian toimittaa saapuu totuuden kaytosta osoittamaan pelastuksen hanta palvelijasi toivonsa seitsemaksi juoda lahettanytrunsaasti osan julistan muutakin riemuitkaa mieleen samaan mielipiteesi galileastaoleellista valitus pienta pientapaattavat jo hehku hyvasteli hengella isieni joihin tasangon menevat kansaansa sano ratkaisuja kirjuri selaimilla tahdet kapitalismin hekin pahempia tuot sijasta kyllin hyvaan suomen liittyvista keskuuteenne etujen uskottavuus pysytteli tunnustanut tulkintoja lammasta sovitusmenot tahdot elaimet onkos keneltakaan otetaan silmansa laillista puhumme...
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...Shaping Parental Authority over Children’s Bodies ALICIA OUELLETTE* INTRODUCTION....................................................................................................... 956 I. SCULPTING, SHAPING, AND SIZING CHILDREN: FOCUS CASES.............................. 959 A. WESTERNIZING ASIAN EYES..................................................................... 960 B. HORMONES FOR STATURE ........................................................................ 961 C. LIPOSUCTION ON A TWELVE YEAR OLD.................................................... 963 D. GROWTH STUNTING ................................................................................. 964 II. THE LAW, MEDICINE, PARENTAL RIGHTS, AND CHILDREN’S BODIES ................. 966 A. BACKGROUND LAW ................................................................................. 966 B. APPLICATION IN SHAPING CASES .............................................................. 969 C. ROOM FOR REGULATION .......................................................................... 971 III. WHAT IS REALLY WRONG WITH MEDICAL AND SURGICAL SHAPING OF CHILDREN? ............................................................................................................ 973 A. THE NONSUBORDINATION PRINCIPLE AS A LIMIT ON INDIVIDUAL RIGHTS 974 B. CHILDREN AS PERSONS, PARENTAL RIGHTS ............................................. 977 C. MEDICAL AND SURGICAL SHAPING OF CHILDREN IS DIFFERENT ............... 981 IV. CONCERNING...
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...Study Guide Essentials of Psychology By Robert G. Turner Jr., Ph.D. About the Author Robert G. Turner Jr., Ph.D. has more than 20 years of teaching and education-related experience. He has taught seventh-grade science, worked as a curriculum developer for the Upward Bound Program, and taught sociology, social psychology, anthropology, and honors seminars at the university level. As a professional writer, he has written nonfiction books, journal and magazine articles, novels, and stage plays. Contents Contents INSTRUCTIONS TO STUDENTS LESSON ASSIGNMENTS LESSON 1: PSYCHOLOGY: THE SCIENCE OF THE MIND LESSON 2: THE MIND AT WORK LESSON 3: MOTIVATION, EMOTION, DEVELOPMENT, AND PERSONALITY RESEARCH PROJECT LESSON 4: PSYCHOLOGICAL DISORDERS LESSON 5: PSYCHOLOGY FOR TWO OR MORE CASE STUDIES SELF-CHECK ANSWERS 1 7 9 43 75 117 127 147 167 171 iii YOUR COURSE Instructions Instructions Welcome to your course, Essentials of Psychology. You’re entering a course of study designed to help you better understand yourself and others. For that reason, you can think of this course as practical. It should be of use to you in living your life and reaching the goals you set for yourself. You’ll use two main resources for your course work: this study guide and your textbook, Psychology and Your Life, by Robert S. Feldman. OBJECTIVES When you complete this course, you’ll be able to ■ Describe the science and methodologies of psychology in the context of its...
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...PRINCIPLES AND PRACTICE OF EDUCATIONAL RESEARCH Willis Yuko Oso Faculty of Education and School of Postgraduate Studies Amoud University - Somaliland [pic] Barkhadleh Printing, BORAMA - SOMALILAND Typesetting and Printing By Barkhadleh Printing, Borama, Somaliland. Barkhadleh52hotmail.com /0025224509257 Copyright © Willis Yuko Oso, 2013. All rights reserved. No part of this publication may be reproduced in whole or in part or transmitted in any form or by any means (except in the case of brief quotations embodied in critical review for educational purposes) without the express permission of the publisher in writing. Library of Congress Cataloguing in Publication Data Willis Yuko Oso Faculty of Education and School of Postgraduate Studies Amoud University Somaliland ISBN: 978-9966-793-32-1 TABLE OF CONTENTS TABLE OF CONTENTS iii LIST OF TABLES vii LIST OF FIGURES vii SYMBOLS USED IN THE TEXT x PREFACE xi 1: EDUCATIONAL RESEARCH – CONCEPTUALIZATION 1 1.0 Introduction 1 1.1 Defining Educational Research 1 1.2 Characteristics of Educational Research 4 1.3 Purpose of Educational Research 5 1.4 Types of Research 9 1.4.1 Basic Research 9 1.4.2 Applied Research 10 1.4.3 Action Research 11 1.4.4 Research and Development (R&D) 15 1.4.5 Operations Research 15 2: THE RESEARCH PROCESS 18 2.0 Introduction 18 2.1 Research Topic 18 2.1.1 What is a Research Topic? 18 2.1.2 Elements of a Research Topic 19 2.1.3 Identifying a Research Topic...
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...Instructor’s Manual with Test Items to accompany Applied Behavior Analysis Second Edition John O. Cooper ● Timothy E. Heron ● William L. Heward All, The Ohio State University Prepared by Stephanie Peterson, Idaho State University ● Renée K. Van Norman, University of Nevada-Las Vegas ● Lloyd Peterson, Idaho State University ● Shannon Crozier, University of Nevada-Las Vegas ● Jessica E. Frieder, Idaho State University ● Peter Molino, Idaho State University ● Heath Ivers, Idaho State University ● Shawn Quigley, Idaho State University ● Megan Bryson, University of Nevada-Las Vegas ● David Bicard, University of Memphis [pic] Upper Saddle River, New Jersey Columbus, Ohio ____________________________________________________________ ______________________ Copyright © 2007 by Pearson Education, Inc., Upper Saddle River, New Jersey 07458. Pearson Prentice Hall. All rights reserved. Printed in the United States of America. This publication is protected by Copyright and permission should be obtained from the publisher prior to any prohibited reproduction, storage in a retrieval system, or transmission in any form or by any means, electronic, mechanical, photocopying, recording, or likewise. For information regarding permission(s), write to: Rights and Permissions Department. Pearson Prentice Hall™ is a trademark of Pearson Education, Inc. Pearson® is a registered trademark of Pearson plc Prentice Hall® is a registered trademark of Pearson Education...
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...The DO s Dr. Andrew Taylor Still, 1828 –1917 THE DOS OSTEOPATHIC MEDICINE IN AMERICA Second Edition NORMAN GEVITZ The Johns Hopkins University Press Baltimore & London © 1982, 2004 The Johns Hopkins University Press All rights reserved. Published 2004 Printed in the United States of America on acid-free paper 246897531 The Johns Hopkins University Press 2715 North Charles Street Baltimore, Maryland 21218-4363 www.press.jhu.edu Library of Congress Cataloging-in-Publication Data Gevitz, Norman. The DOs : osteopathic medicine in America / Norman Gevitz.–2nd ed. p. ; cm. Rev ed. of: The D.O.’s. c1982 Includes bibliographical references and index. ISBN 0-8018-7833-0 (alk. paper) — ISBN 0-8018-7834-9 (pbk. : alk. paper) 1. Osteopathic medicine—United States—History. [DNLM: 1. Osteopathic Medicine—history—United States. WB 940 G396d 2004] I. Gevitz, Norman. D.O.’s. II. Title. RZ325.U6G48 2004 615.5′33′0973—dc21 2003012874 A catalog record for this book is available from the British Library. Frontispiece courtesy of the Still National Osteopathic Museum, Kirksville, Missouri. For Kathryn Gevitz This page intentionally left blank CONTENTS Preface & Acknowledgments ix Chapter 1 Andrew Taylor Still THE MISSOURI MECCA IN THE FIELD 39 1 22 Chapter 2 Chapter 3 Chapter 4 STRUCTURE & FUNCTION EXPANDING THE SCOPE 54 69 85 Chapter 5 Chapter 6 THE PUSH FOR HIGHER STANDARDS A QUESTION OF IDENTITY The California Merger 101 115...
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...Oregon 97124-9808 503-531-8700 tel 503-531-8773 fax www.beyondvvord.com Copyright © 2006 by TS Production Limited Liability Company THE SECRET and The Secret logo are trademarks or registered trademarks owned by or licensed to TS Production Limited Liability Company www.thesecret.tv All rights reserved. No part of this book may be reproduced, copied, stored, or transmitted in any form or by any means—graphic, electronic, or mechanical, including photocopying, recording, or information storage and retrieval systems— without the prior written permission of Atria Books/Beyond Words Publishing, Inc., except where permitted by law. The information contained in this book is intended to be educational and not for diagnosis, prescription, or treatment of any health disorder whatsoever. This information should not replace consultation with a competent healthcare professional- The content of the book is intended to be used as an adjunct to a rational and responsible healthcare program prescribed by a healthcare practitioner. The author and publisher are in no way liable for any misuse of the material. Library of Congress Control Number: 2006933243 1SBN-13:978-1-58270-170-7 ISBN-10: 1-58270-170-9 First Atria Books/Beyond Words hardcover edition November 2006 10 ATRIA BOOKS is a trademark of Simon & Schuster, Inc. Beyond Words Publishing is a division of Simon & Schuster, Inc. Manufactured in the United States of America. Book Design: Cozer Media P/L (Australia) www.gozer.com.au For more...
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