Free Essay

Anatomy

In:

Submitted By sfellis1
Words 3330
Pages 14
Anatomy & Physiology II EXAM 1 Notes:
CHAPTER 17: ENDOCRINE SYSTEM
17.1
-You have to have the communication and control network for your 100,000,000 cells
-Communication System: NERVOUS * Functions: 1. Collects Information 2. Processes Information 3. Initiates Response * Communication Method:
-Nerve signal travels along the neuron then the neurotransmitter is released into the synaptic cleft * Target Cells: 1. Other Neurons 2. Muscle Cells 3. Gland Cells * Response Time: RAPID * Duration of Response: SHORT (terminates with removal of stimulus)
-Communication System: ENDOCRINE (Chemical Communication System) * Functions: 1. Maintaining homeostasis 2. Regulating development, growth, and metabolism 3. Controlling Reproductive Activites * Communication Method:
-Produces and releases hormones-regulatory chemicals (proteins or lipids) secreted into the blood stream and affects target cells. * Target Cells:
-A variety of cells with a specific receptor for a hormone that initiates or inhibits selective cell activities. * Response Time: LONGER * Duration of Response: LONGER LASTING (mins to days and weeks)
17.2
-Endocrine Cells: 1. Derived from epithelium with connective tissue framework 2. Have extensive blood supply to facilitate rapid uptake of hormones 3. Two Locations:
-Single Organ: pineal, thyroid, pituitary, parathyroid, and adrenal glands
-Cells in small clusters in organs with another primary function: stomach, liver, pancreas
-Endocrine glands: scattered throughout the body and interact to maintain homeostasis * Example: Pineal Gland-posterior region of the epithalamus that secretes MELATONIN (Pineapple is a melon) that helps regulate circadian rhythm (makes us drowsy at night) and is involved in the regulation of maturation. * The Pineal Gland decreases in size as we age. * Example: Parathyroid Gland- contains 4 nodules on the posterior surface of the thyroid gland. Their CHIEF CELLS produce parathyroid hormone that increases blood calcium levels. * The parathyroid also contains oxyphil cells, which an overabundance can cause oxyphil cell adenoma
-Major Endocrine Glands: -Organs that Contain Endocrine Cells: 1. Pituitary 1. Hypothalamus 6. Small Intestine 2. Pineal 2. Thalamus 7. Pancreas 3. Parathyroid 3. Skin 8. Kidneys 4. Thyroid 4. Liver 9. Gonads 5. Adrenal 5. Stomach
-Stimulation of hormone synthesis and release
-Secretion of a hormone is controlled through a reflex * Endocrine Reflex- pre-programmed response to certain stimuli * 3 types of Stimulation: 1. Hormonal- release of a hormone in response to another hormone 2. Humoral- (“humor” =fluid of the body) changes into blood composition triggers a response from certain glands to return nutrients or ions to the normal level 3. Nervous-by signal from the nervous system
17.3
-Major categories of hormones: * All circulatory hormones are synthesized within endocrine cells from either cholesterol or amino acids. 1. Steroid Hormone 2. Protein Hormone 3. Biogenic Amine
-Lipid Soluble -Water Soluble -water Soluable
-Formed from cholesterol -formed from Amino Acids -formed from MODIFIED AA
-Local Hormones (clusters of cells)-a large group of signaling molecules that do not circulate within the blood. They bind with same cell or neighboring cells. * Eicosanoid- (“twenty formed”)= primary hormone
17.4
-Water soluble hormones (PROTEINS AND BIOGENIC AMINE)-cannot pass through membrane because of bilayer; readily dissolve and move through blood
-Lipid soluble hormones(STEROID)- DO NOT readily dissolve and require carrier proteins synthesized by the liver. * In addition, carrier proteins protect hormones from early destruction (this is why some water soluable hormones are transported by carrier protein molecules)
17.5
-Hormones have contact with all tissues of the body, but interact only with target cells that possess and appropriate receptor
-Lipid Soluble hormones are small, nonpolar molecules: 1. Diffuse across plasma membrane 2. Bind to intracellular receptors and form hormone-receptor complex 3. Hormone-receptor complex binds to a specific area of DNA called hormone-response element that initiates the synthesis of a certain protein
-example: testosterone enhances muscle development
-Water soluble hormones are polar molecules unable to cross the plasma membrane, so they have to bind to a plasma membrane receptor, thus initiating a series of biochemical events (signal transduction pathway) 1. Hormone is first messenger 2. Docking of the hormone results in the formation of a second molecule(second messenger) that will modify some cellular activity
-Activation of G Protein: (SWITCH) 1. Hormone (first messenger) binds to the receptor and induces shape change to activate the receptor. 2. G Protein binds to activated receptor 3. GDP (guanine diphosphate) is “bumped off” and GTP (guanine triphosphate) binds to G Protein, activating it. 4. Activated G Protein (with GTP) is released from the receptor and moves along the inside of the plasma membrane, which results in formation or availability of the second messenger
-Activated G Protein will go on to activate ONE of TWO enzyme cascades:
A) Adenylate Cyclase Activity 1. Activated G Protein binds to and causes activation of the plasma membrane enzyme adenylate cyclase 2. Adenylate cyclase converts ATP molecules to cAMP molecules 3. cAMP serves as the “second messenger” by activating protein kinase A (phosphorylating enzyme that activates OR inhibits other molecules by adding a phosphate to them
B) Phospholipase C Activity 1. Activated G Protein binds to and causes activation of the plasma membrane, phospholipase C 2. Phospholipase C splits PIP2 (a phospholipid molecule within plasma membrane) into 2 second messengers a. DAG=diaclyglycerol b. IP3= inositol triphosphate
-DAG activates Kinase C
-IP3 increases Ca2+ in cytosol (from ER or Interstitial fluid)
-Ca2+ acts as a 3rd messenger to: 1. Activate protein kinase enzymes (directly or through calmodulin) 2. Alter activity of ion channels within the plasma membrane
-Action of water soluble hormones-multiple results possible with hormone activation * Activation or inhibition of enzymatic pathways * Stimulation of cellular secretions * Muscle contraction or relaxation
17.6
-A cell’s response to a hormone caries at different times because: 1. The same target cell can display different number of receptors for the same hormone a) up-regulation: cells increase number of receptors in a response to reduced hormone concentration in the blood. b) down-regulation: cells decrease the number of receptors in response to elevated hormone concentration in the blood * Receptor fluctuation also occurs as a result of:
-Developmental maturity, cells state of activity, and different stages of cell cycle
G Protein---GTP
G Protein---GTP 2. The target cell with receptors for various hormones will respond differently based on how the hormones interact.

Phospholipase C
(enzyme)
Phospholipase C
(enzyme)
Adenylate Kinase
(enzyme)
Adenylate Kinase
(enzyme)

ATP cAMP (2nd mess) PIP2 DAG&IP3 (2nd mess) Increases Ca2+ Activation of Protein Kinase Activation of Protein Kinase
17.7
-Review Concepts: 1. Some organic molecules can be oxidized to provide energy to form ATP- these are called “Nutrients.” Major nutrients are: glucose, fatty acids, and some amino acids. 2. Nutrients circulate in the blood in their simple form, but they can also be stored. a. Glucose is stored as glycogen b. Fatty acids are stored as triglycerides c. Amino Acids are stored as proteins 3. Through intracellular enzymatic pathways, nutrients can be deposited and withdrawn here to maintain homeostasis. This blood level of nutrients is highly regulated by various hormones
7.8
-Hypothalamus: * Has DIRECT control over hormone release from pituitary gland. * Has indirect control over hormone release from: thyroid, adrenal, liver, testes, and ovaries
-Pituitary: hypophysis * Connected to hypothalamus by “stalk” or the infundibulum * Partitioned into anterior and posterior pituitary 4. Anterior pituitary: adenohypophysis
-develops from ectoderm in oral cavity
-3/4 pituitary mass
-3 areas: 1. pars distalis 2. pars tuberalis 3. pars intermedia
-hypothalamo-hypophyseal portal system-a capillary network connecting the hypothalamus and hypophysis. It allows hypothalamus to release 7 regulatory hormones affecting the anterior pituitary 5. Posterior pituitary: Neurohypophysis
-formed from developing hypothalamus.
-composed of: infundibulum and pars nervosa
-cell bodies and dendrites of about 10,000 neurosecretory neurons are located within the hypothalamic nuclei. They synthesize several hormones and transport them to the pars nervosa for storage. a. oxytocin- labor contractions and milk letdown b. antidiuretic hormone-urine output
-Hormones are released into the blood stream from the posterior pituitary when a nerve signal is sent from the hypothalamus
-Hormones regulated by Hypothalamus: * Released
1.THYROTROPIN 4. PROLACTIN 2. GONADOTROPIN 5. GROWTH HORMONE 3. CORTICOTROPIN * Inhibiting
1. PROLACTIN
2. GROWTH HORMONE
-Hormones of Anterior Pituitary: 1. THYROTROPIN 4. PROLACTIN 2. GONADOTROPIN 5. GROWTH HORMONE 3. ADRENOCORTICOTROPIC H
-Hormones of another endocrine gland involved: 1.THYROID H 2. Sex hormones synthesized by gonads 3. Glucocorticoids from adrenal gland
-Growth Hormone: regulated by the hypothalamus * Release controlled by growth hormone releasing hormone(GHRH) * Release is influenced by age, time of day, nutrient levels, stress, and exercise
-Thyroid Gland: * Regulated by Hypothalamus * Largest structure in the body devoted to endocrine activities (20-30 g) * Has left and right lobes, connected by a narrow isthmus (butterfly) and is highly vasculated * Composed of microscopic spherical structures called thyroid follicles that produce thyroid hormone * Follicular cells form a wall surrounding a central lumen that houses protein rich colloid
-Thyroid hormone production: * IODINE is transported into the colloid * THYROGLOBULINS, a protein rich in tyrosine amino acids is synthesized in follicular cells and transported into the colloid * Iodine is added to the tyrosine rings to form MIT
DIT+MIT=T3 or DIT +DIT=T4 * Some colloid internalizes by endocytes into a follicular cell and delivered to a lysosome where an enzyme cuts off T3 and T4 * Mature hormones are released into the blood stream
-Action of the Thyroid Hormone: * Release of the thyroid hormone is under the control of the hypothalamus is the anterior pituitary in response to: * Decreased blood levels of thyroid hormone * Cold weather, pregnancy, or hypoglycemia * Thyroid hormone targets a variety of cells increasing metabolic rate and body temperature. * Increase release of nutrients stored into blood and their use by other body cells * Increase respiration and heart rate to meet the growing oxygen demands * Parafollicular cells (C-cells)-located adjacent to thyroid follicles produce and secrete calcitonin * Decreases blood Calcium level in 3 ways: 1. Inhibits Ca2+ absorption by intestines 2. Inhibits osteoclasts in bone 3. Increases Ca2+ excretion in urine
-Calcitonin opposes the effect of parathyroid hormone(PTH)
-Adrenal Gland: * Regulated by the hypothalamus * Paired, pyramid shaped glands located on the superior surface of each kidney; subdivided into two regions * Adrenal Cortex-(outer) yellow color due to lipid (steroid) content A. Zona glomerulosa- (thin, outer layer) synthesizes MINERALCORTICOIDS to regulate salt and water balance B. Zona fasciculata- (middle layer) synthesizes GLUCOCORTICOIDS to regulate glucose metabolism and immune responses C. Zona Reticularis-(inner layer) sex hormone and GONADOCORTICOID regulation * Adrenal Medulla-(inner) red brown color due to extensive blood vessels, and releases CATECHOLAMINES(epinephrine and norepinephrine)
-Cortisol: type of glucocorticoid * Release is controlled by CORTICOTROPIN-releasing hormone produced by hypothalamus. The cortisol is then transformed into ADRENOCORTICOPIC HORMONE (ACTH) from anterior pituitary—cortisol released by adrenal glands * Cortisol is released: * As a part of the normal daily cycle: (highest before awakening) * In response to both emotional and physical stress * Functions: * Increase nutrient levels in the blood (esp. glucose) to assure adequate fuel to keep you functioning * Suppresses immune system to prevent overactivity
17.9
-The adrenal medulla contains chromatin cells which are the modified neurons of the ANS * Synthesize catecholamines * The sympathetic ANS exerts direct control over the chromaffin cells in response to stress EEE (emergency, exercise, and excitement), medullary cells release catecholamines into blood
-Effects of epinephrine and norepinephrine: * Fight or Flight Response
Fight or Flight Response
Increased heart rate and blood pressure * Blood vessel constriction * Increased metabolism

17.10
-Anatomy of the Pancreas: * Elongated organ between the duodenum and spleen; posterior to the stomach * Performs endocrine and exocrine activities * Contains: 1. Pancreatic acini-produces alkaline pancreatic juice released into the small intestine to aid in digestion 2. Pancreatic islet cells-(1%) small clusters of endocrine cells: * Alpha cells-secretes GLUCAGON * Beta cells-secretes INSULIN * Delta Cells- secretes SOMATOSTATIN * F-Cells-secretes PANCREATIC POLYPEPTIDE * Major pancreatic/endocrine function is: Maintaining Blood Glucose Level * INCREASED blood glucose level=damages blood vessels * DEFREASED blood glucose level=lethargy, mental impairment
-Lowering Blood Glucose Level with Insulin-META CELLS -After food intake, high glucose levels are detected by beta cells that respond by releasing insulin (it will facilitate nutrient take up and storage) 1. HEPATOCYTES take up glucose and store as glycogen 2. Adipose tissue takes up glycerol and fatty acids 3. Most cells make up amino acids 4. Various cells take up glucose (only if they have glucose transport proteins)
-Raising the Blood Glucose Level with Glucagon * Glucagon is released by alpha cells in response to low Blood glucose levels * Facilitates nutrient breakdown and release: 1. HEPATOCYTES release glucose into blood 2. Adipose tissue releases fatty acids and glycerol from storage in blood 3. Has no effect on protein components to avoid destruction of skeletal, muscular, and other structural proteins in low glucose situations
CHAPTER 18
-Functions of the circulatory system: 1. Transportation (delivery of gasses, nutrients, and hormones) 2. Regulation(temp, pH, fluid balance) 3. Protection( from pathogens and blood loss after injury)
-Components of the Circulatory system: 1. Blood-fluid connective tissue 2. Blood vessels-hollow tubes that direct blood a. Arteries-carry blood away from the heart b. Veins-take blood to the heart c. Capillaries-permeable, microscopic vessels joining arteries and veins 3. Heart- functions to pump blood
18.1
-Physical characteristics of Blood: A. Color-depends on oxygenation status
-oxygenated=bright red
-deoxygenated=dark red B. Volume: around 5L in an adult (essential for maintaining blood pressure) C. Viscosity-4-5 times more viscous than water D. Temperature-1°C higher than the measured body temperature (it warms as it travels) E. Blood pH- slightly basic (pH between 7.35-7.45) ; with pH alteration, proteins become denatured
-Components of blood: A. Whole Blood: blood drawn from the body in which no constituent has been removed B. Centrifuged blood: separated by centrifuge into 3 components: 1. Plasma-55% i. Water(92%) ii. Proteins(7%) iii. Other solutes(1%) 2. Buffy Coat(41%) iv. Platelets v. Leukocytes 3. Erythrocytes
18.2
-Plasma has similar composition to interstitial fluid, but protein concentration is higher in plasma than interstitial fluid: 1. Water-medium in which formed elements are suspended and carious molecules are dissolved 2. Plasma proteins-collectively all blood proteins exert colloid osmotic pressure that is responsible for running water into capillaries, preventing excess fluid loss between blood capillaries and the interstitial fluid= helping to maintain correct blood V and P. a. Albumins- (58% of total proteins) small proteins that transport hormones, some fatty acids, ions, and some play the major role in maintaining blood-colloid osmotic pressure b. Gllobulins(37% of total proteins) large proteins transporting lipids and metal ions. Immunoglobulins are defensive proteins that attack pathogens c. Fibrogen (4% of total proteins) contributes to blood clot formation (plasma-clotting proteins= serum) d. Regulatory proteins(less than 1%) enzymes and some hormones 3. Other solutes(1%) blood contains dissolved organic and inorganic molecules and ions including electrolytes, gas, nutrients, and waste products
18.3
-Formed Element: Erythrocytes -Life Span: 120 days -Density: 4.8 million in females; 5.4 million in males -Functions: carry and transport oxygen and carbon dioxide filled with hemoglobin that is responsible for oxygen and carbon dioxide
-Formed Elemend:Leukocytes -Life Span: 12 hours to years -Density: 4500-11,000 -Function: defend against harmful substance
-Formed Elemend:Thrombocytes(Platelets) -Life Span: 8-10 days -Density: 150,000-400,000 -Function: blood clotting
-Since most formed elements have a relatively short life span, there is a continual production of formed elements=hemopoesis 1. Occurs in the red bone marrow of certain bones 2. Involves hemocytoblasts (blood stream cells that can diffenteriate into many types of blood cells influenced by regulatory chemicals called colony-stimulating factors(CSFs)
-Formed elements in the blood: Erythrocytes -Small: lack nucleus and cellular organelles -Shape: bioconcave discs -Flexible: has a latticework of membrane proteins that provides support and flexibility -Content-35% hemoglobin molecules * Hemoglobin-red pigmented protein that transports oxygen and carbon dioxide * Oxyhemoglobin-bound to oxygen * Deoxyhemoglobin-not bound to oxygen * Carbaminohemoglobin-bound to carbon dioxide
-Hemoglobin structure: * Composed of 4 polypeptides-globulins * Each globulin has a heme group=porphyrin ring+ iron ion in center * One oxygen molecule
Binds to the Fe2+ in each heme group to be transported though the blood
-Erythrocyte destruction: * The absence of both a nucleus and cellular organelles disables protein synthesis of erythrocytes= short life span of around 120 days * Old erythrocytes are disassembled in the spleen or the liver * Globin proteins are broken down into free amino acids and reused by the body. * Fe2+ is transported to the liver by a protein, ferritin. Iron will be delivered to the red bone marrow for the erythrocyte producing as needed * Porphyrin ring is metabolically altered and excreted from the body: * With feces—in the form of brown strecobilin(destruction of RBC’s is normal and good) * With urine—in the form of yellow urobin
-Formed elements in the blood: Leukocytes * Characteristics: * Contain nucleus and organelles * Some have visible, large granules (granulocytes) have some small granules, visible under a microscope (agranulocytes) * Great defense cells * Motile * Can enter body tissues by diapedesis squeezing through the endothelial cells of capillaries * Capable of following chemical signals released by other cells (chemostaxis) * Cell type: Neutrophils(50-70%) * Features: MULTIlobed nucleus, cytoplasm with pale granulocytes * Function: enter tissue to phagocytize pathogen (especially bacteria) * Cell Type: Esoinophils(1-4%) * Features: BIlobed nucleus, cytoplasm with reddish granules * Function: Phagocytes, allergies, and attacks parasitic worms * Cell Type: Lymphocytes(20-40%) * Features: dark, staining rounded nucleus; resides in lymphatic organs and structures * Functions: manage immune responses a) T-lymphocytes b) B-lymphocytes c) NK cells (natural killer) * Cell Type: Monocytes(2-8%) * Features: c-shaped nucleus * Functions: when enter tissues—transforms into dendritic cells OR macrophages “big eaters”
18.4
-Hemostasis: process of stopping blood flowing through the injured blood vessel wall 1. Vascular spasm (contraction)—several minutes a. Sudden constriction of blood vessels that limits blood leakage from the vessel. Greater vasoconstriction with greater vessel damage 2. Platelet plug formation(1 minute) b. Under the normal conditions, endothelial wall is smooth because it is coated with an eicosanoid, prostacyclin, that acts as a platelet replacement
-When vessel is damaged: i. The collagen fibers in the vessel wall become exposed ii. Platelets start sticking here assisted by Von Willebrand factor, plasma protein injury due to formation of platelet plug c. Platelets undergo morphologic change and becomes activated, releasing various chemicals to assist with hemostasis
Ex. Thrombin A2 (type of eicosanoid) will strengthen vascular system and attract other platelets -other chemicals will simulate coagulation and tissue repair. 3. Blood Clotting (Coagulation) d. Most important and complex component of hemostasis e. Clot is an insoluble protein network composed of fibrin with other elements of blood trapped f. Requires Calcuim, Vitamin K g. Clotting factors-inactive enzymes produced in the liver h. Vitamin K-fat soluble vitamin required for synthesis of several clotting factors(coenzyme)
-There are 2 ways to initiate the coagulation cascade: intrinsic and extrinsic pathways. They converge to the common pathway a) Intrinsic pathway(3-6 min)-initiated by platelets after the damage to the vessel wall i. Factor XIII-PLATELTES ii. Factor XI iii. Factor IX-Calcium iv. Factor VIII v. Goal is to produce fibrin polymer
Goal is to produce fibrin polymer
FACTOR X b) Extrinsic pathway(15 sec) vi. Damaged perivascular tissues vii. Factor III viii. Factor VII ix. Calcium x. FACTOR X
-The Sympathetic response to blood loss -If greater than 10% of blood lost== sympathetic response initiated (causes vasoconstriction, rapid heart rate, force of heart contraction & blood redistributes to heart and brain) FIGHT-OR-FLIGHT **This is effective in maintaining blood pressure until 40% of blood lost, then it is insufficient blood volume to support life.
-Hemostasis: elimination of the blood clot a) Clot retraction: occurs as clot is forming. Contractile proteins within platelets contract, helping to bring the sides of the vessels closer together to repair the damage b) Fibrinolysis- degradation of fibrin strands by plasmin, begins within the 2 days after clot formation
Clot formation and clot elimination, if imbalanced, can lead to various bleeding or blood clotting disorders

Similar Documents

Premium Essay

Anatomy

...Anatomy is the branch of biology concerned with the study of the structure of animals and their parts; it is also referred to as zootomy to separate it from human anatomy. In some of its facets, anatomy is related to embryology and comparative anatomy, which itself is closely related to evolutionary biology and phylogeny.[1] Human anatomy is one of the basic essential sciences of medicine. The discipline of anatomy is divided into macroscopic and microscopic anatomy. Macroscopic anatomy, or gross anatomy, is the examination of an animal’s body parts using unaided eyesight. Gross anatomy also includes the branch of superficial anatomy. Microscopic anatomy involves the use of optical instruments in the study of the tissues of various structures, known as histology and also in the study of cells. The history of anatomy is characterized by a progressive understanding of the functions of the organs and structures of the human body. Methods have also improved dramatically, advancing from the examination of animals by dissection of carcases and cadavers (corpses) to 20th century medical imaging techniques including X-ray, ultrasound, and magnetic resonance imaging. Contents 1 Definition 2 Animal tissues 2.1 Connective tissue 2.2 Epithelium 2.3 Muscle tissue 2.4 Nervous tissue 3 Vertebrate anatomy 3.1 Fish anatomy 3.2 Amphibian anatomy 3.3 Reptile anatomy 3.4 Bird anatomy 3.5 Mammal...

Words: 652 - Pages: 3

Premium Essay

Anatomy

...As far as we know, anatomy is the oldest medical science. Cave paintings of the early Stone Age, about 30,000 years ago,* show a simple knowledge of the anatomy of animals, and it is assumed that these cave dwellers applied some of their anatomical knowledge to their own bodies. The civilizations of the Babylonians, as Syrians, Egyptians, Chinese, and Hindus made no serious attempt to learn anatomy because they were interested in the supernatural world, not the natural one, and their cultures placed strong religious restrictions against debasing the body. Any anatomical dissections that were performed on animals were made to "study" organs in an effort to predict the future and to tell fortunes. *The Stone Age, the earliest known period of human culture, is characterized by the use of small stone tools. Anatomy in Ancient Greece The systematic study of anatomy may have begun in the fifth century B.C ., with the work of two Greek scientists, Alcmaeon (ca. 500 B.C.) in Italy andEmpedocles (ca. 490-430 B.C) in Sicily, where Greek culture and science flourished. Alcmaeon was probably the first person to dissect the human body for research purposes, and he is also given credit for proposing that the brain is the center of intelligence. Empedocles, who believed that the heart distributed life-giving heat to the body, initiated the idea that an ethereal substance called pneuma, which was both life and soul, flowed through the blood vessels. Although such early anatomists were often...

Words: 1472 - Pages: 6

Free Essay

Anatomy and Physiology

...Summary Week 1 Discussion This discussion we looked at two examples of the heart and its functions. Atrial septal defect (ASD) is fairly common. This was a terrific example to relate structure and function. When the structure of anatomy is disrupted we can see as in this example how normal function is altered. This congenital defect allows blood to flow between atria instead of the normal flow through the ventricles and to the body and the disrupted and limited blood flow can lead to heart failure, stroke and pulmonary hypertension. The larger the hole the more quickly surgery is needed to correct it. Smaller holes may provide enough blood flow to avoid these complications and may heal over on its own. Ventricular septal defect (VSD) is less common. A hole between the ventricles allows mixing of oxygenated blood from the lungs with de-oxygenated blood returning from the body. Heart failure and infections occur rapidly due to the lack of oxygenated blood reaching the body and the baby often presents with a bluish discoloration to the skin as a result of lack of oxygen. Artificial hearts being developed run on batteries to pump the blood and include porting valves to ensure blood flow goes in the correct direction. Essential characteristics of an artificial heart that would make them ideal would be to mimic the real heart in structure and function and resist rejection in the recipient. References Atrial septal defect (ASD). (2014). Retrieved from http://www.heart...

Words: 348 - Pages: 2

Free Essay

Anatomy

...PH 104: ANATOMY I/IV FIRST YEAR FIRST SEMESTER Introduction: Anatomy is a basic science subject dealing with the knowledge of the structure of the human body in health. Mastery of the subject lays a foundation for understanding other basic science subjects, and clinical subjects in subsequent years. The pharmacy anatomy course consists of a single module of lectures and seminars. Objectives: At the end of the course the students should be able to:- Describe the structure of the human body as seen by the naked eye in health. Identify different parts of the human body. Use medical/anatomical terminology. Describe physiological processes in health and disease using the anatomy terms. Describe the processes involved in the development of the human body. Describe congenital malformations and how they come about and the times when drugs can have teratological effect. UNIT I Introduction to Anatomy: Components of Anatomy, Methods for learning Anatomy, Anatomical terminology Introduction to Cell Biology and Medical Genetics, General introduction to tissues of the body, Epithelial tissue, Connective tissue UNIT II Human skeletal system: Types of bone, Histology of bone, Individual bones, Human Anatomy of major joints, Applied anatomy Human Muscular system: Histology of muscle tissue, Organization of different type of muscle, skeletal muscles UNIT III Human Alimentary system: Components and general organization; Gross anatomy, Histology of different components, Applied...

Words: 369 - Pages: 2

Premium Essay

Anatomy and Physology

...Osteoporosis is a disease where decreased bone strength increases the risk of a broken bone. It is the most common reason for a broken bone among people who are old. Bones that commonly break include the back bones, the bones of the forearm, and the hip. Until a broken bone occurs there are typically no symptoms. Bones may weaken to such a degree that a break may occur with minor stress or spontaneously. Chronic pain and a decreased ability to carry out normal activities may occur following a broken bone. Postmenopausal osteoporosis is the most common form of osteoporosis. It affects many women after menopause, leaving some women up in age such as an 84 year old slim, small boned female at high risk for fracture. Osteoarthritis is a type of joint disease that results from breakdown of joint cartilage and underlying bone. The most common symptoms are joint pain and stiffness. Initially, symptoms may occur only following exercise, but over time may become constant. Other symptoms may include joint swelling, decreased range of motion, and when the back is affected weakness or numbness of the arms and legs. The most commonly involved joints are those near the ends of the fingers, at the base of the thumb, neck, lower back, knees, and hips. Joints on one side of the body are often more affected than those on the other. Usually the problems come on over years. It can affect work and normal daily activities. Unlike other types of arthritis, only the joints are typically affected. ...

Words: 366 - Pages: 2

Premium Essay

Anatomy Intro

...Lewis: Human Anatomy and Physiology, 12th ed. Chapter 1: Introduction to Human Anatomy and Physiology Chapter 1: Introduction to Human Anatomy and Physiology I. Introduction A. The interests of our earliest ancestors most likely concerned injuries and illness because healthy bodies demand little attention from their owners. B. Primitive people certainly suffered from occasional aches and pains, injuries, bleeding, broken bones, and diseases. C. Before agriculture, infectious diseases did not spread easily because isolated bands of people had little contact with each other. D. With agriculture, humans became susceptible to worm diseases because excrement was used in fertilizers and less reliance was placed on wild plants that offered their protective substances. E. With urbanization, humans became more susceptible to infectious diseases and malnutrition. F. Tooth decay was lowest among hunter-gathers and highest among city residents. G. Preserved bones from children can reflect malnutrition because when a child starves or suffers from severe infection, the ends of the bones stop growing. When health returns, growth resumes, but leaves behind areas of dense bone. H. At first healers had to rely on superstitions and notions about magic. I. The forerunners of modern drugs were herbs and potions. J. Early medical providers developed the language of anatomy and physiology from Greek and Latin. II. Anatomy and Physiology A. Anatomy is the study...

Words: 2527 - Pages: 11

Free Essay

Reflection on Intro to Physiology/Anatomy

...We started with the introduction to anatomy by defining it as the scientific discipline that investigates the structure of the body. I have discovered that there are two basic approaches to the study of anatomy are systematic (by system) and regional (by area), the latter which is more commonly used in most medical schools. And of course studying the structure is not enough, this is where physiology comes in which is the scientific discipline that deals with the processes or functions of living things. I have known homeostasis as the maintenance of the relatively constant environment in the body but it is only now that I have learned about positive and negative feedback mechanisms which maintain homeostasis and that positive homeostasis can be detrimental at times. I’ve also learned more on the anatomical terms that will be used throughout our course and maybe even in med school. In the study of cells, I was able to recall the things we have discussed in our biological science course in the previous year. I remember the three types of solution namely hypotonic, isotonic, and hypertonic. I also come to know more about the different movements across the cell membrane. However I was new to the transcription and translation that happens in the gene expression of a cell. I was able to associate codons of the mRNA strand with the anticodon of the tRNA. Similar to cytology, I was also able to look back on our discussions about tissues last year. I have refreshed myself on the...

Words: 472 - Pages: 2

Free Essay

Anatomy I

...Sarahbeth Cook May 12, 2011 Anatomy I Professor Kriota Willberg It is rare to find someone with a complete and perfect symmetrical body. Every human being has his or her own skeletal structure and no one is alike. If you are one of those few people lucky enough to have “perfect symmetry and balance,” you might end up finding a flaw elsewhere, or so I’d like to think. For myself, being as active of a dancer that I am, I already put a tremendous amount of wear and tare on my body, especially since I’ve been studying for eighteen years. The chances of me being perfectly in balance are slim to none. No matter how much physical therapy I do on my body, if I continue to dance with extreme physical motion I will always have something that is not in place. After doing these assessments I discovered a few things I didn’t realize about my body, but after analyzing them I see how they possibly may trigger some of my areas of discomfort. These imbalances affect my everyday activities, physical comfort, range of motion, and general sense of well-being. I have the privilege of having a physical trainer to assist me at work before every performance. She’s there to make sure my imbalances are cared for and I’ve been given exercises to strengthen my weak areas. The main areas I’ve decided that need major work consist on my shoulders, spine, core, and ankle/foot. I’ve selected a series of exercises that I believe will help improve my weaknesses. My overall posture is very good and that...

Words: 1421 - Pages: 6

Premium Essay

Intro to Anatomy & Physio

...1: The Human Body: An Orientation I. An Overview of Anatomy and Physiology (pp. 1–3) A. Anatomy is the study of the structure of body parts and their relationships to each other, and physiology is the study of the function of body parts (p. 2). B. Topics of Anatomy (p. 2) 1. Gross (macroscopic) anatomy is the study of structures large enough to be seen with the naked eye. a. Regional anatomy is the study of all body structures in a given body region. b. Systemic anatomy is the study of all structures in a body system. c. Surface anatomy is the study of internal body structures as they relate to the overlying skin. 2. Microscopic anatomy is the study of structures that are too small to be seen with the naked eye. a. Cytology is the study of individual cells. b. Histology is the study of tissues. 3. Developmental anatomy is the study of the change in body structures over the course of a lifetime; embryology focuses on development that occurs before birth. 4. Specialized Branches of Anatomy a. Pathological anatomy is the study of structural changes associated with disease. b. Radiographic anatomy is the study of internal structures using specialized visualization techniques. c. Molecular biology is the study of biological molecules. 5. Essential tools for studying anatomy are the mastery of medical terminology and the development of keen observational skills. ...

Words: 2871 - Pages: 12

Premium Essay

Grey's Anatomy Comparison

...Grey’s Anatomy stars Sarah Drew, Jessica Capshaw to leave show Medical drama Grey’s Anatomy recently announced the departure of longtime stars and fan favorites Sarah Drew and Jessica Capshaw. Both are expected to exit the popular TV series after the conclusion of season 14. Both actresses are veterans of the show, with Drew having been a cast member for the past nine seasons and Capshaw for the past ten. Their characters, Sarah Drew’s April and Jessica Capshaw’s Arizona, have long been fan favorites on the program and are notable for representing groups that are less visible on many TV shows. Drew’s April Kepner drew acclaim from many Christian groups for her devoutly Christian background while Capshaw’s Arizona Robbins was hailed by LGBT...

Words: 373 - Pages: 2

Premium Essay

Anatomy and Physiology 1

...BIOL 2010 LEARNING OBJECTIVES 1. 1.1. 1.2. 1.3. 1.4. 1.5. 1.6. 1.7. 2. 2.1. 2.2. 2.3. 2.4. 2.5. 2.6. 2.7. 2.8. 2.9. 2.10. 2.11. 2.12. 2.13. 2.14. 2.15. 2.16. 2.17. 2.18. 2.19. 2.20. 2.21. Describe the physical organization of the human body and explain how interaction between body components is critical for the maintenance of homeostasis. Define the terms anatomy and physiology in reference to the human body. (LECT & LAB) Describe each of the following levels of organization of the human body: chemical, cellular, tissue, system, organism. (LECT & LAB) Identify the principal systems of the body. (LECT & LAB) Describe the standard anatomical position of the human body. (LECT & LAB) Compare common anatomical terms used to describe the various regions of the human body. (LECT & LAB) List by name and location the principal body cavities. (LECT & LAB) Define homeostasis and explain the effects of the lack of homeostasis on the body's function. (LECT & LAB) Describe the chemical level of organization of the human body. Describe the interrelationship of matter, elements, and atoms. (LECT) Identify by name and symbol the principal elements of the human body. (LECT) Diagram and label the structure of a typical atom. (LECT) Describe the function of electrons located in incomplete outer energy levels. (LECT) Define the terms isotope and radioisotope and give their functions. (LECT) Describe the three types of chemical bonding (ionic...

Words: 2061 - Pages: 9

Premium Essay

Sc121 Unit 1 Anatomy Essay

...Patterson, Shawn SC121-Unit 1- Seminar 1 Seminar 1 Option 2 Assignment “Anatomy is the study of the structure of living organs.” “Physiology is to study and understanding of how living organisms live and keep them alive.” Anatomical position is when the position with the body the position with the body upright and having the arms at their side and their palms forward. The anatomical position is important in anatomy because it is the position of reference for anatomical nomenclature. Anatomical terms such as lateral means toward the side away from the mid section of your body. Medial is the opposite which is toward the middle away from the side of the body. Proximal is closer to the origin of your body and distal is farther...

Words: 510 - Pages: 3

Free Essay

Sc121 Unit 1 Lets Talk Anatomy

...Let’s talk anatomy Anatomy is the science of body structures and the relationships among them. It is all around us, it is basically us. The human anatomy deals with basically all the parts of humans, dealing with molecules to bones to the way we function, but that can also get misinterpreted for Physiology which is the study of body functions and how the body parts work, which in this case it is something different. Anatomy and Physiology are two concepts that are related to each other, as stated before anatomy is the science of body structures and the relationship among them, while Physiology is the study of body functions and how body parts work together. Now, with all of that being said Anatomy differs from physiology in many ways, the study of anatomy usually focuses on the shape, size, and where they are usually located at. In my perspective anatomy is more like dissection of the body, you can easily cut up the body and with your very own eyes see what the body is, or in more scientific forms using a microscope for a more detailed view. A person can easily see what they are encountering on a body and what system is connected to what. In physiology its rather more vigorous mostly involving different types of properties (chemical, physical or electrical) that make the body function. Beginning from the process of how our heart rate is regulated to more difficult systems involving different visual perceptions. Physiology is usually involved with the work of living...

Words: 1038 - Pages: 5

Premium Essay

Grey's Anatomy Research Paper

...Trauma, the O.R room, death and tears is what you will find in Grey's Anatomy. Grey’s Anatomy is a drama based out of Seattle and focuses on a group of doctors/ surgeons. These doctors are starting out at the hospital as interns and the show follows them through till they are doctors and it shows the struggles and such that they have. Grey’s Anatomy can be watched on Netflix or on Thursday nights on ABC. Grey’s Anatomy has been on television since 2005 and it currently has 14 seasons. Ellen Pompeo is one of the main actors in this tv series. She plays the main role of Meredith Grey. Meredith is trying to follow in her mother's footsteps and become the best surgeon she could be. The show it based around her experiences and the people she meets...

Words: 258 - Pages: 2

Premium Essay

Greys Anatomy: Chapter Summary

...Greys Anatomy Greys Anatomy tells a story about Meredith Grey who got accepted into Seattle Grace Mercy West Hospital. She was assigned to work under Miranda Bailey along with Christina Yang, Izzie Stevens, George O’Malley and Alex Karev. Greys Anatomy focuses on surgical interns, residents and attending’s as Meredith and the rest of her team evolve into surgical doctors, while trying to maintain personal lives. Miranda Bailey is referred to the new interns as “The Nazi” because she is very straight forward and demands respect. On the first day for Meredith, Christina, Izzie, George and Alex, Miranda starts off by saying “Don’t bother sucking up because I already hate you and that’s not going to change” however later on in the show she starts to show...

Words: 1094 - Pages: 5