...1.2.1 Exposure to long term antibiotic therapy Long-term antibiotic therapy is one of the most extensively studied risk factors. Exposure to multiple and prolonged use of broad spectrum antimicrobials have been found to be independent risk factors for candidemia. The reason for this being, many of the antibiotics like beta-lactams and vancomycin used in the wards and intensive care unit (ICU) settings lead to the depletion of normal bacterial flora resulting in fungal overgrowth. The increasing use of oral vancomycin in the ICUs results in the depletion of anaerobic bacterial flora of the gut. 1.2.2 Intravascular Catheters and Central Venous Catheters Intravascular catheters are also one of the important risk factors in the acquisition of candidemia. Candida species adhere avidly to materials used in intravascular catheters and provide a potential nidus for infection. Some species like Candida parapsilosis are especially implicated in intravascular catheter-related infections in neonates and in the paediatric age group. The role played by intravascular catheters in perpetuating candidemia has implications for its management. Removal of vascular catheters has been advocated as an adjunctive strategy for treating patients with catheter-related candidemia. However, there is some controversy regarding the benefits and risks of removal of vascular catheters in management of candidemia....
Words: 1726 - Pages: 7
...According to the research article on “Compliance with surgical antibiotic prophylaxis at an Australian teaching hospital” (Friedman, Styles, Gray, Low, & Athan 2013, p. 71) the use of certain antibiotics and or combinations for prevention of surgically related infections has shown to be an effective method in prevention of surgical site infections. The focus of the research was to measure to effectiveness of prophylactic use of antibiotics in regards to surgical procedures such as cardiac, orthopedic joint replacements, and colorectal procedures. The American Journal of Infection Control listed the following key elements of focus which were “(1) receipt of prophylaxis within 1 hour before surgical incision, (2) administration of an antimicrobial agent consistent with published guidelines and (3) discontinuation of SAP within 24 hours after surgery” (Friedman et al., 2013). The research was conducted at a teaching hospital in Victoria, Australia. The time span that the data was collected took 33 months total. The data gathered in...
Words: 748 - Pages: 3
...Screening and Decolonization of MRSA in the Preoperative Patient Suzanne Miller Aspen University HUM410 Abstract Staphylococcus aureus is the most common organism responsible for surgical site infections. The colonization of Methicillin-resistant staphylococcus aureus (MRSA) has been identified as a significant risk factor for patients undergoing orthopedic surgery, putting this patient at a higher risk of developing a surgical site infection. Screening preoperatively and treating colonization is a tool to aid in the prevention of surgical site infections in patients undergoing elective joint surgery. Results of various studies of patients undergoing elective joint replacement surgery have been reviewed. A nasal swab was obtained and cultured during preadmission testing. If the culture showed that the patient was positive for MRSA colonization they were treated with nasal mupirocin. They also were instructed to bathe with surgical wipes containing chlorhexidine prior to the procedure. The results of the research suggest that the use of a screening protocol prior to surgery can decrease the risk of MRSA in the postoperative patient. Table of Contents 1. Literature Review........................................................................................................................4 2. Discussion....................................................................................................................................7 3. Conclusion................
Words: 2617 - Pages: 11
...Hygiene: * Hand washing, hand antisepsis, or surgical hand antisepsis, substantially reduces potential pathogens on the hands and is considered the single most critical measure for reducing the risk of transmitting organisms. * For routine dental examinations and nonsurgical procedures, hand washing and hand antisepsis is achieved by using either a plain or antimicrobial soap + water (15 sec.). If the hands are not visibly soiled, an alcohol-based hand rub is adequate (until it dries~15 sec). It should be done: * Before glove placement and after glove removal. * After barehanded touching of infected objects. * Before leaving the dental office. * When visibly soiled. * After removing gloves that are torn, cut, or punctured. * For surgical procedures, surgical hand antisepsis with an antimicrobial soap (2-6 min.) or alcohol hand rub with persistent activity should be used. * Antimicrobical soap include: (chlorhexidine, iodine and iodophors and triclosan) * Fingernails should be unpolished, short enough to allow DHCP to thoroughly clean underneath them and prevent glove tears. * All hand jewelry should be removed, except for plain wedding ring. 4- Personal Protective Equipments * Worn in the order: Protective clothing, Mask, Eye glasses and finally the Gloves. c) Gloves * Their selection should be based on the type of procedure to be performed : * Patient examination gloves...
Words: 1152 - Pages: 5
...WHO Guidelines on Hand Hygiene in Health Care: a Summary First Global Patient Safety Challenge Clean Care is Safer Care a WHO Guidelines on Hand Hygiene in Health Care: a Summary © World Health Organization 2009 WHO/IER/PSP/2009.07 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: bookorders@who.int). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: permissions@who.int). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable...
Words: 27087 - Pages: 109
...Aeromonas Hydrophila: The Improbable Culprit Edwin Myrick Abstract This study examines the structure and influences of Aeromonas Hydrophila, as a stand-alone bacterium and as it contribute to Necrotizing Fasciitis. Aeromonas Hydrophila impacts both aquatic life and humans, although the infection is not commonly known. This study examines those influences and explores medical case studies where individuals experienced illness, amputation, and even death. Aeromonas Hydrophila: The Improbable Culprit As the summer months begin to elevate the mercury level, nature’s creeks and streams provide cooling entertainment from the elements. People have long used these waterways for recreation activities, such as fishing, walking, swimming, and canoeing; unsuspecting of the dangers. Most bacteria are harmless, but certain types can cause complications and disease. The flesh eating bacteria Aeromonas Hydrophila, can create unthinkable devastation through minor cuts and scratches; causing sickness, amputation, and even death. The world has thousands of micro-living organisms called bacteria, these unicellular microorganisms have cell walls, but no structured nucleus, some of these microorganisms can cause disease (Hogan, 2005). Thousands of bacteria inhibit our environment every day, many of them unidentified but not all of them are unhealthy. Bacterial cells consist of shapes; spherical, rodlike, spiral, helical, and comm-shaped (Lerner, 2005). The...
Words: 1944 - Pages: 8
...How can communicable diseases be broken at a link within the communicable disease chain? Are there steps that a nurse can take to facilitate this process? Give a specific example. Use an example that is different than the postings of other students. There are six links in the Chain of Infection. Those areas include: 1. The infectious agent itself- 2. The reservoir where the infectious agent can live and multiply or lie dormant until the organism can find the opportunity to cause disease 3. The susceptible host 4. A means of Transmission 5. A portal of exit 6. A portal of re-entry Each link in this chain must be intact for a disease to be transmitted and infect another person. There is the potential to defeat a communicable disease process by disrupting the link in this chain at any point along the way thus preventing infection in another person. An example of the simplest chain of infection is an infected patient cared for by a health care worker who doesn't wash their hands before caring for another patient. Human sources of microorganisms are healthcare workers, patients themselves and visitors, any of whom may be individuals who are in some stage of an incubation period of a disease process, may already have a disease, or may be a chronic carrier of an infectious agent. The patient may be their own source of infection. (Baldwin, 2008) The bacteria must be able to find a susceptible host. Some individuals are immune to infection or are able to resist...
Words: 2021 - Pages: 9
...treatment of these infectious diseases (Titilope et al., 2012), both infectious and non-infectious. Attah et al. (2012) makes similar claims with the evaluation and development of compounds from similar claims with the evaluation and development of compounds from medicinal plants for the treatment of diseases which is one of the areas that is gaining grounds and acceptability world-wide (p.1). According to the World Health Organization, medicinal plants would be the best source to acquire different effective drugs and, therefore, those plants should undergo investigation to have a better understanding of their properties, safety and efficacy (Rajeh et al., 2010; Nascimiento et al., 2000). There are some published reports describing the antimicrobial activity of various crude plant extracts (Igoli et al., 2005; Alzoreky et al., 2003). It is estimated that there are about 2.5 million species of higher plants and the majority of these have not yet been examined for their pharmacological activities (Ram et al., 2003). In relation with the applications of herbal plants, weed, which is a plant that grows out of place and is competitive, persistent and pernicious (James et al., 1991), have been a part of civilization and many ancient documents speak of humans battling weeds in the crops they grow and also found to be resistant to most of the microbial disease that made us interested to know the potency behind (Ibrahim et al., 2012). Furthermore, according to Ibrahim et al. (2012), there...
Words: 3671 - Pages: 15
...Nosocomial Infections By princessbec76 | Studymode.com Section 1: Infections in Healthcare Settings Essay. Nosocomial infections, hospital acquired infections, are an on-going concern to healthcare professionals. These infections are one of the major causes of death in hospitalised patients and are a significant burden on not only the patient’s and the public’s health (as organisms causing nosocomial infections can be transmitted to the community through discharged patients, staff and visitors) but also the economy. A nosocomial infection is an infection acquired at least 72 hours after being admitted into hospital for any reason other than the infection or one which develops amongst hospital staff. Infections are also identified as nosocomial if they appear in a patient within 30 days after their discharge from hospital. Non nosocomial infections, community acquired infections, are infections acquired anywhere other than the hospital. The most common places where non nosocomial infections occur are schools, day care centres and sports facilities. They are spread through skin to skin contact, cuts and grazes, overcrowding and poor hygiene. The illnesses or infections can be the same, for example, pneumonia or gastroenteritis but it is the setting that they are contracted in which differentiate the two infections. Nosocomial infections occur worldwide and affect both wealthy, developed countries as well as the poorer ones with scarce resources. A survey conducted by the World...
Words: 1639 - Pages: 7
...Chapter I Background of the Study The twentieth century has witnessed tremendous advances in the understanding of infectious diseases, but many problems remain. Skin diseases are a common threat to humans that could be prevented by antibiotic treatment. Carbuncle, a skin disorder, is caused by Staphylococcus aureus bacteria that may occur as a commensal and may affect other tissues when normal barriers have been breached. Researchers around the globe developed antibiotics, such as penicillin and glycopeptides that could kill or slow down the growth of S. aureus bacteria. By 1950, it was reported that 40% of the hospital S. aureus isolates were penicillin and glycopeptide resistant; and recently, this has risen to 80%. Microciona prolifera, or red sponge, contains substances with antibiotic capacity that could kill or slow down the growth of a strain of S. aureus bacteria suggesting possibilities for creating novel drugs to treat the infectious skin disease. This study aims to determine the most efficient antibiotic solution of ectyonin extract from Microciona prolifera against Staphylococcus aureus bacteria. Statement of the Problem General Problem This study aims to compare which of the different solutions of Ectyonin extract from Microciona prolifera is the most effective in inhibiting the growth of the bacteria. Specific Problem Specifically it aims to answer the following questions: 1. Which of the four solutions...
Words: 3591 - Pages: 15
...Darshana T. Durup and John A. Bosso Antimicrob. Agents Chemother. 2010, 54(1):109. DOI: 10.1128/AAC.01041-09. Published Ahead of Print 19 October 2009. Downloaded from http://aac.asm.org/ on January 1, 2012 by guest Updated information and services can be found at: http://aac.asm.org/content/54/1/109 These include: REFERENCES This article cites 43 articles, 12 of which can be accessed free at: http://aac.asm.org/content/54/1/109#ref-list-1 Receive: RSS Feeds, eTOCs, free email alerts (when new articles cite this article), more» CONTENT ALERTS Information about commercial reprint orders: http://aac.asm.org/site/misc/reprints.xhtml To subscribe to to another ASM Journal go to: http://journals.asm.org/site/subscriptions/ ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jan. 2010, p. 109–115 0066-4804/10/$12.00 doi:10.1128/AAC.01041-09 Copyright © 2010, American Society for Microbiology. All Rights Reserved. Vol. 54, No. 1 Attributable Hospital Cost and Length of Stay Associated with Health Care-Associated Infections Caused by Antibiotic-Resistant Gram-Negative Bacteria Patrick D. Mauldin,1,2 Cassandra D. Salgado,3 Ida Solhøj Hansen,1 Darshana T. Durup,1 and John A. Bosso1,3* Department of Clinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy,1 Ralph H. Johnson VA Medical Center,2 and Division of Infectious Diseases, Medical University of South Carolina College of Medicine,3 Charleston, South Carolina Received 24 July 2009/Returned for modification...
Words: 7936 - Pages: 32
...The n e w e ng l a n d j o u r na l of m e dic i n e Clinical Practice Caren G. Solomon, M.D., M.P.H., Editor Urinary Tract Infections in Older Men Anthony J. Schaeffer, M.D., and Lindsay E. Nicolle, M.D. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors’ clinical recommendations. From the Feinberg School of Medicine, Northwestern University, Chicago (A.J.S.); and the University of Manitoba, Winnipeg, Canada (L.E.N.). Address reprint requests to Dr. Schaeffer at the Feinberg School of Medicine, Northwestern University, 303 E. Chicago Ave., Tarry Bldg. 16-703, Chicago, IL 60611, or at jschaeffer@ a northwestern.edu. N Engl J Med 2016;374:562-71. DOI: 10.1056/NEJMcp1503950 Copyright © 2016 Massachusetts Medical Society. An audio version of this article is available at NEJM.org 562 A 79-year-old community-dwelling man presents with urinary frequency, dysuria, and fever. Culture reveals extended-spectrum beta-lactamase Escherichia coli. He had a similar infection several months ago, with the same organism isolated, and he had a response to nitrofurantoin treatment. How would you further evaluate and manage this case? U The Cl inic a l Probl em rinary tract infection in men without indwelling catheters is uncommon among men younger...
Words: 6651 - Pages: 27
...Aacknowledgement First of all I like to thank God almighty who authorise me to research on this topic. I submit my sincere thanks to my supervisor Medhat Khattar for his valuable presence, time, effort, guidance and help to complete this dissertation. My dissertation would not have been completed without the help of lab technicians Nick and Suzy, I am extremely grateful for their help, suggestions and encouragement. I might want to thank my family for impacting in me a comprehension for the significance of education and an appreciation for diligent work. I extraordinarily value the majority of the penances that were made so as to realize the open doors that I have gotten, and it is my trusts that this proposition embodies what I have realized. Much obliged to you for your dedication, bolster, and affection. I might likewise want to thank my grandparents for the numerous hours of math mentoring as a youngster. In spite of the fact that it may have appeared to be inconsequential, it was the premise for my prosperity and the establishment of my hobbies in Designing. I might want to devote this proposition to my family, without whom I would not be seeking after a profession with an instruction from my university undergraduate days. I also thank my supervisor’s effort and good work channelled towards making me a better microbiologist in the world. I sincerely extend my thanks all concerned people who together with me in this regard. Table of Contents I Declaration......
Words: 14532 - Pages: 59
...Chapter 1 INTRODUCTION Background Euphorbia hirta, belongs to the family of Euphorbiaceae which is a large family of dicotyledons, with about 300 genera and over 5,000 species. Here in the Philippines, the Euphorbia hirta, is commonly referred to as Tawa-tawa or Gatas-gatas in some provinces. It is also known as Asthma weed or Snake weed in the United States. The plants of 3 different species share Phoretic variations, these plants are: (1) Mutha (Cyperus rotundus), (2) Gatas-gatas (Euphorbia hirta) and (3) Botoncillo (Gomphena globosa). Tawa-tawa is usually very abundant in tropical regions such as the Philippines. A simple weed scattered in sunny lawns, waste places and open grasslands. It is pantropic in distribution. The plant is an annual, hairy herb, usually branched from the base, spreading up to 40 cm long. The stem is slender and often reddish and purplish in color, covered with yellowish bristly hairs especially in younger parts. The leaves are oppositely arranged, elliptical-oblong to oblong-lanceolate, 1 to 2.5 cm long, toothed at the edge, and blotched with purple in the middle. In the axils appear numerous involucres, purplish or greenish, dense, axillary, short stalk clusters or crowded cymes, about 1 mm long. The capsules are broadly ovoid, hairy, three-angled, about 1.5 cm. The small green flowers constitute the inflourescence characteristics of the euphorbias. The stem and the leaves produce white or milky juice when cut (Lind and Tallantire...
Words: 8195 - Pages: 33
...------------------------------------------------- Applications of Epidemiology – A Case Study Shaneil White July 19, 2015 hSA505 Dr. Chad Moretz July 19, 2015 hSA505 Dr. Chad Moretz Analyze Good Health Hospital’s records and itemize recent nosocomial infections that occurred within the past year. In your report, categorize the different parameters (i.e., person, time, place, ethnicity, and gender) used in the compilation of data into the nformation summative. Currently at the Good Health Hospital, there’s a nosocomial outbreak of E. coli on Ward 10 on the second floor. Four cases have been identified so far linked to spoil food from the cafeteria, with two more cases pending. After meeting with chief administrator Joe Wellborn, one patient could possibly been symptomatic with the bacteria prior to admission. Parameters discussion below: * Person: 4 identified cases. (1. Male, age 23), (2. Female, age 21), (Male, age 15), and (Female, age 42). * Place: Good Health Hospital, Ward 10, second floor; Good Health Hospital cafeteria. Also research has indicated that other area hospitals around Tampa Bay has been contaminated with E. coli as well. * Time: Within the past week. Propose at least six (6) questions for the health care administrator at Good Health Hospital, regarding potential litigation issues with infections from the nosocomial diseases. Rationalize, in your report, the logic behind your six (6) questions. Traditionally, nosocomial infections have generally...
Words: 2061 - Pages: 9
