Centralized Operations at North Campus Research Complex (NCRC): 1600 Huron River Drive, Ann Arbor, Michigan (visiting); 2800 Plymouth Road – Building 400, Ann Arbor, Michigan 48109-2800 (mailing). In 2009, the University of Michigan purchased a 174-acre, 30-building research campus formerly occupied by Pfizer. The campus includes research laboratories, research and administrative office space, collaboration and training venues, and a cGMP manufacturing facility. This purchase provides an unprecedented opportunity for the creation of a transformational, interdisciplinary research campus. MICHR played a leading role in the creation of this new campus by being "pioneers" - MICHR clinical research service staff were among the first occupants of the new campus and are now co-located with the IRB, clinical research billing, Cancer Center Clinical Trials Office staff, and many others, creating a clinical research administration "hub" allowing an unprecedented level of communication, collaboration, and sharing of best practices between these entities.

MCRU Distributed Research Performance Sites: The Michigan Clinical Research Unit (MCRU) is currently located in three discrete areas. The main performance site is on level 1 in the UMHS Cardiovascular Center (CVC). The Domino's Farms extension is located approximately four miles from the hospital in northeast Ann Arbor. The Rachel Upjohn Building extension is on the East Ann Arbor Medical Center Campus.

The MCRU facility in the CVC comprises approximately 7,400 square feet of space, which includes research-only outpatient exam rooms, research-only overnight stay beds in private rooms, and administrative offices. It also includes a research exercise physiology area, a procedure room, a nursing workspace, a medical preparation and storage room, a patient/subject intake area, equipment storage space, clean and soiled holing rooms, a principal investigator and study coordinator workroom, a staff locker room, a metabolic kitchen, a specimen processing laboratory, a patient waiting area, and a dining area for participants.

The Outpatient Clinical Research Unit at Domino's Farms currently houses 10 exam rooms, including a research physiology room. All aspects of the unit are JCAHO-compliant. Shared space includes a waiting room, patient carrels, patient intake area, equipment room, a double secure-locked documentation room, audit/exam room, patient food preparation room, staff kitchen, patient shower, and handicap accessible bathrooms. A 140-square-foot wet laboratory is contiguous with the patient facility. It contains two table top centrifuges, one computer with internet connection allowing follow-up on patient laboratory values, one label printer for blood draws, and supplies for drawing blood and for preparing aliquots for storage. The laboratory also contains a small specimen refrigerator, two -86° specimen freezers, and one -20° specimen freezer.

Five additional research-only dental suites have been added by the Dental School, as part of their partnership with MICHR.

The Minority Health Research Program MCRU clinic is located at the Ypsilanti Health Center (YHC), a satellite health center of U-M Hospital and Health Centers. Two departments make up the YHC - the Department of Family Medicine and Department of Pediatrics. Space dedicated to MCRU - 430 square feet - includes two exam rooms, a small laboratory, a nurse's office, and lobby space used for check-in and check-out and for displaying educational materials.

The Human Applications Laboratory (HAL) occupies approximately 1,500 square feet of laboratory space on the seventh floor of the University of Michigan Hospital. The HAL is maintained and managed by a dedicated staff, receives leadership through a HAL director, and is regularly audited by the University of Michigan Health System Corporate Quality Improvement Good Tissue Manufacturing and Laboratory Practices Coordinator. The HAL is physically divided into three distinct areas: an administrative records management office, a class 10,000 clean room, and a room for flow cytometry characterization of cellular products. Access to all three areas is strictly controlled and monitored.

The Michigan Clinical Research Unit (MCRU)
North Campus Research Complex (NCRC)