Babe Ruth was 53 when he died (1895-1935) .
He had died of Esophageal Cancer.
Esophageal Cancer is a disease in which malignant (cancer) cells form in the tissues of the esophagus. The esophagus is a muscular tube that moves food and liquids from the throat to the stomach. The most common types of esophageal cancer are squamous cell carcinoma and adenocarcinoma.
Babe Ruth was and will always be remembered as a great baseball player because of his records and sportsmanship.