BACK THE TRUCK UP!/Ch.2-3
1. Disorders of the neonate may involve any system and are broken down into the following types.
Congenital, Genetic, and Teratogenic
2. Disorders of the neonate cause ½ of all deaths in term newborns.
True
3. A major anomaly in disorders of the neonate is usually apparent at birth in 3 to 4% of newborns.
True
4. Which disorder or syndrome is most likely caused by a teratogen?
Fetal Alcohol syndrome
5. The recessive disorders are easy to detect using carrier screening and have a high morbidity and mortality.
True
6. What tow primary (least evasive) approaches are used to monitor fetal growth, development, and to identify pregnancy risks for a congenital anomaly?
Maternal serum screening and ultrasonography
7. Five percent of all pregnant women screened will have abnormal test results when there is an unaffected pregnancy.
True
8. Maternal Serum Screening can detect the risk for which condition?
Possible Neural Tube Defect
9. The leading indication for invasive diagnostic is advanced maternal age.
True
10. What would be the outcome for an autosomal recessive trait, statistically speaking, if a person who is a heterozygous carrier has children with a homozygous normal individual? (Use Boxes)
Fifty percent of the children will be carriers and fifty percent will be normal.

11. Maternal Serum Screening is considered diagnostic test used to determine the type of disorder your baby will have when born.
False
12. Which serum blood levels indicate the probability of neural tube defect?
High AFP
13. What are the risks involved for a female who wishes to become pregnant at the age of forty-five?
There is a 1 in 20 chance of Down syndrome other chromosomal abnormality.
14. Amniocentesis is done between fifteen and eighteen weeks after the last menstrual period.
True
15. What is Polydactylism?
The possession of more than the normal number of digits.
16. Susceptibility of the fetus to congenital abnormalities depends on what factor(s).
Genetic sensitivity and Timing
17. Which term below indicates the site of fetal placenta development?
Endometrium
18. Which term below indicates the type of cells that differentiate into skin, spinal cord, and teeth?
Ectoderm
19. Which term below indicates the type of cells that differentiate into blood vessels, muscles bone?
Mesoderm
20. Which term below indicates the type of cells that differentiate into lungs, digestive, and urinary systems?
Endoderm
21. The period from three weeks to eight weeks after ovulation and fertilization is called..
The embryonic period
22. Which best describes the current knowledge of congenital malformations?
Two-thirds of the known malformations have an unknown cause.
23. Exposure under 5 rad of radiation in associated with risk for congenital disorders.
True
24. Which medication was used to control nausea and vomiting in the first trimester, but also caused severe birth defect such as absents of part of the small intestines, limb reductions, anomalies, microtia (small ears), and spinal malformations?
Thalidomide
25. Which best describes the condition known as encephalocele?
Skull malformation with protruding brain (occipital region)
26. Which best describes the condition known as Anencephaly?
Indicates severe malformation with no neural development above brainstem
27. Which best describes the condition known as Spina Bifida?
Split of section of the vertebral arches and the split may be isolated or occur with a protruding sac.
28. Which best describes the condition known as Meningomyelocele?
Individuals are born with a membranous sac covering the spinal cord called a meningeocele.
29. Which congenital condition can occur if palatal shelves do not begin to extend vertically in a downward fashion?
Cleft lip or pallete
30. With inheritance of an X-linked dominant disorder, statistically speaking, what would the outcome between a homozygous recessive female with a hemizygous dominant male?
All daughters will have the gene but not the sons
31. With inheritance of an autosomal dominant disorder, statistically speaking, what would the outcome between a heterozygous individual with a homozygous, unaffected individual?
50% affected and 50% normal
32. Words to know:
Diploid

Zygote

Blastocyst

Morula

Suggested intake of calories

Protein, fats, complex carbs