...DRUG DEVELOPMENT SCIENCE Obstacles and Opportunities for Collaboration Among Academia, Industry and Government January 13–14, 2005 Washington, DC David Korn, M.D. Donald R. Stanski, M.D. Editors DRUG DEVELOPMENT SCIENCE Obstacles and Opportunities for Collaboration Among Academia, Industry and Government Report of an Invitational Conference Organized by The Association of American Medical Colleges Food and Drug Administration Center for Drug Development Science, at the University of California, San Francisco January 13-14, 2005 Washington, DC David Korn, M.D. Donald R. Stanski, M.D. Editors DRUG DEVELOPMENT SCIENCE ACKNOWLEDGEMENTS This is the report of a conference convened by the Association of American Medical Colleges and the Food and Drug Administration in response to the FDA white paper entitled “Innovation or Stagnation: Challenge and Opportunity on the Critical Path to New Product Development”. The conference was partially supported by the FDA. The AAMC acknowledges with gratitude the additional support provided by Abbott Laboratories, Cephalon, Inc., Eli Lilly and Company, GlaxoSmith Kline, Merck & Co. Inc., and Pfizer, Inc. The conference planning committee consisted of Drs. David Korn, Joel Kupersmith, Carl Peck, Donald Stanski, and Janet Woodcock. Figures 1 and 2 are taken from the FDA white paper. The back cover composite is derived from charts presented at the conference by Dr. Peter Corr, Pfizer, Inc. The report was designed by Douglas Ortiz, AAMC...
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...A Review of Literature Related to Oil Spill Dispersants 1997-2008 for Prince William Sound Regional Citizens’ Advisory Council (PWSRCAC) Anchorage, Alaska by Merv Fingas Spill Science Edmonton, Alberta PWSRCAC Contract Number - 955.08.03 Disclaimer: The opinions expressed in this PWSRCAC-commissioned report are not necessarily those of PWSRCAC September, 2008 ii Abstract This report is a review of the literature on oil spill dispersants published from 1997 to August, 2008. The report identifies and focusses on recent advances in dispersant effectiveness, toxicity, and biodegradation. Other topics such as application, use, behaviour and fate are also covered. The prime motivation for using dispersants is to reduce the impact of oil on shorelines, thus the application must be successful and effectiveness high. As some oil would come ashore, discussion remains on what effectiveness is required to significantly reduce the shoreline impact. A major issue is the actual effectiveness during spills so that these values can be used in estimates for the future. The second motivation for using dispersants is to reduce the impact on birds and mammals on the water surface. The benefits of using dispersants to reduce impacts on wildlife still remain unknown. The third motivation for using dispersants is to promote the biodegradation of oil in the water column. The effect of dispersants on biodegradation is still a matter of dispute. Some papers state that dispersants inhibit...
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...Business Plans Handbook Business Plans A COMPILATION OF BUSINESS PLANS DEVELOPED BY INDIVIDUALS NORTH THROUGHOUT AMERICA Handbook VOLUME 16 Lynn M. Pearce, Project Editor Business Plans Handbook, Volume 16 Project Editor: Lynn M. Pearce Product Manager: Jenai Drouillard Product Design: Jennifer Wahi Composition and Electronic Prepress: Evi Seoud Manufacturing: Rita Wimberley Editorial: Erin Braun ª 2010 Gale, Cengage Learning ALL RIGHTS RESERVED. No part of this work covered by the copyright herein may be reproduced, transmitted, stored, or used in any form or by any means graphic, electronic, or mechanical, including but not limited to photocopying, recording, scanning, digitizing, taping, Web distribution, information networks, or information storage and retrieval systems, except as permitted under Section 107 or 108 of the 1976 United States Copyright Act, without the prior written permission of the publisher. This publication is a creative work fully protected by all applicable copyright laws, as well as by misappropriation, trade secret, unfair competition, and other applicable laws. The authors and editors of this work have added value to the underlying factual material herein through one or more of the following: unique and original selection, coordination, expression, arrangement, and classification of the information. For product information and technology assistance, contact us at Gale Customer Support, 1-800-877-4253. For permission to use material...
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...Leadership Development Seminars and ECQ-based Readings The success or failure of any endeavor depends on leadership. Now, more than ever before, we need leaders in our organizations and in our world. Great leaders create and communicate a vision and move people into action to achieve it. They ignite our passion and inspire us to do our best. Government leaders in the 21st century are experiencing change at a more rapid pace than previous generations. Rapid advances in technology have expanded the quantity of work we are capable of accomplishing, and also where it’s accomplished. We have a more highly educated workforce, yet face diminishing resources with an increased demand for productivity, and the essential services we provide to the American public. To be successful at navigating these challenges leaders must develop the essential skills to motivate their employees, effectively communicate with others, fine-tune critical thinking skills, and build and leverage partnerships. Future leaders must also be visionary; i.e., possess the ability to identify trends and the courage to be innovative. Being technically adept in your field will no longer be enough. In response to these demands on senior executives, the U.S. Office of Personnel Management identified five Executive Core Qualifications (ECQs) that all aspiring government leaders and executives must possess. These ECQs and Fundamental Competencies were developed by OPM after extensive research on the attributes...
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...Leadership Development Seminars and ECQ-based Readings The success or failure of any endeavor depends on leadership. Now, more than ever before, we need leaders in our organizations and in our world. Great leaders create and communicate a vision and move people into action to achieve it. They ignite our passion and inspire us to do our best. Government leaders in the 21st century are experiencing change at a more rapid pace than previous generations. Rapid advances in technology have expanded the quantity of work we are capable of accomplishing, and also where it’s accomplished. We have a more highly educated workforce, yet face diminishing resources with an increased demand for productivity, and the essential services we provide to the American public. To be successful at navigating these challenges leaders must develop the essential skills to motivate their employees, effectively communicate with others, fine-tune critical thinking skills, and build and leverage partnerships. Future leaders must also be visionary; i.e., possess the ability to identify trends and the courage to be innovative. Being technically adept in your field will no longer be enough. In response to these demands on senior executives, the U.S. Office of Personnel Management identified five Executive Core Qualifications (ECQs) that all aspiring government leaders and executives must possess. These ECQs and Fundamental Competencies were developed by OPM after extensive research on the attributes...
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...文勇的新托福精选阅读（原黄金29篇）真题[2010年4月3日 5.8版本] 俺常常收到同学们的邮件，要我推荐各种各样阅读材料,问我iBT的复习资料中 Barron, Longman, Delta等等哪个更好。我其实很无奈---因为尽管这些机构很大牌,但大牌丝毫都不意味着文章“质量高”(比如你可以想想三鹿奶粉)---说这些机构的文章质量不高,并不是说文字写得不好,而是说这些文章的句子结构, 论述方式, 出题思路与ETS的并不一致(有时候甚至大相径庭)：用这样的材料训练，实在是 事倍功半。 于是，我们实在应该去找找由ETS出的iBT文章来做：（我们能够找到的|由ETS编纂的标准iBT文章有） 1. OG[1]之中的13篇文章[2]；（其中3篇为第三版OG之中的文章） 2. 13次（套）TPO[3]之中的3*13=39篇文章[4]； 3. 早期[5]报名之时ETS赠送的3篇在线测试题 4. ETS官方给出的模考软件之中抽出的1篇文章； 于是这个文档在我的一时兴起之下，出现了： OG拿在手上，可以一个个字的敲成电子版；TPO的所有考试都是在自己的计算机进行，于是可以一边花钱参加考试,一边截图与录像---再利用截下来的图片，逐个的敲下来；早期的ETS赠送的3篇在线测试题，我也恰好有电子版本；官方的模考软件稍微用点功夫，就能将文章提取并复制出来。虽然工作有些繁杂，但总算完成了所有文章的敲打工作。再花了些时间，把这53篇文章都做了答案，附在文章的后面。（由于TPO之中有3篇文章与OG中完全重复,于是减去3篇,只剩下53篇。）同时我还更正了OG上几个明显的错误（详见文后附录）当然，我还做出了方便大家理解文章的参考译文，附在文章的后面。 在这53篇由ETS出的文章没有做完之前，我们实在不应该花时间在任何其他的题目之上。我有时候甚至会对着我的弟兄们高呼：“没有把这53篇做３遍，你好意思上考场么？你好意思花钱在任何一本垃圾书上面么？[6]” 另外，如果你正在准备iBT-SAT-GRE的作文部分或者写留学文书，也应该仔细的琢磨一下这些文章：经过ETS打磨的文章，无一不是精妙绝伦，极具模仿价值。常常有同学拜托我帮她（他）写PS，也说起自己的句子怎么看都像是小学生写的（尽管用上了GRE里面的单词），于是会随口问我“勇哥，您的写作能力是怎么训练出来的。”我说，“看呗，看呗：托福文章看多了，写作能力自然就提高了。” “这ETS的这些文章真的那么好？”。每当听到这个问题，我都会装做赵本山的样子来一句“谁用谁知道～～” 文勇 欢迎进行未删节的转载|且不必告诉我你转载到哪里去|都是一个战壕里面的弟兄啊… 告诉大家一个好消息，本文档中的TPO1-TPO9，以及在线测试题和官方模考题目的解析已经在市面上可以买到了！（好吧，我承认以下显然是广告部分）： 这本《托福真题详解-阅读分卷-第一册》是给弟兄们现在市面上可以获得的TPO1-TPO9阅读部分的文章解析，题目解析，中文翻译和每篇文章的必备词汇：文章解析是为了让大家养成从整体抓文章结构的感觉，题目解析是为了使大家能够在做完题之后知道正确选项为什么对，错误选项为什么错——并且因此来培养良好的做题思路，中文翻译是为了帮助大家扫除那些自以为理解对但实际理解有误的句子，在每篇文章后面配上必备词汇无非是为了节省大家的一些查单词而已。 另外，这本书还包含了一张CD（我想你可能第一次听说阅读书...
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...INDEX S.NO. TOPIC INDIAN CONTRACT ACT Nature and Kind of Contracts Offer and Acceptance of an Offer Capacity of Parties and Consideration Void Agreement and Contingent Contract Performance of Contract Discharge of a Contract Remedies for Breach of Contract and Quasi-contract Agency PAGE 2-10 11-22 23-34 35-49 50-62 63-72 73-81 82-99 SALES OF GOODS ACT Sales of Goods Act CONSUMER PROTECTION ACT Consumer Protection Act NEGOTIABLE INSTRUMENT ACT Negotiable Instrument Act THE PARTNERSHIP LAW The Partnership Law THE COMPANIES ACT 1956 & COMPANIES LAW 2013 Companies Act 1956: Types of Company and Its Characters 101-127 129-140 142-167 169-191 193-211 Companies Act 1956: Memorandum, Article of Association and 212-239 Prospectus Companies Act 1956: Share Capital Companies Act 1956: Meeting Companies Act 1956: Management of the Company Companies Act 2013 240-275 276-302 303-340 341-364 THE CYBER LAW 2000 & AMENDMENTS IN 2008 CASES 0 MODULE-1 INDIAN CONTRACT ACT 1872 Chapters 1. Nature and Kind of Contracts 2. Offer and Acceptance of an Offer 3. Capacity of Parties and Consideration 4. Void Agreement and Contingent Contract 5. Performance of Contract 6. Discharge of a Contract 7. Remedies for Breach of Contract and Quasi-contract 8. Agency 1 The Indian Contract Act 1872: Nature and Kind of Contracts Learning Objectives In this chapter, students will come to know What is an agreement and a contract? What are the essential...
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...ั ิ สนติ สงหว ังชา ~ 1 ~ yoyo's investing way www.yoyoway.com ั ิ สนติ สงหว ังชา 2006-2010 รวบรวมโดย พร ์ บญชนะวว ัฒน ์ ี ุ ิ https://www.facebook.com/WizardKidTrader YOYO'S WAYS ~ 2 ~ yoyo's investing way Year 2006 www.yoyoway.com ั ิ สนติ สงหว ังชา ~ 3 ~ ั ิ ื “สนต ิ สงหว ังชา” (YOYO) เสอหนม..ไฟแรง ุ่ จากดกรในการจัดการพอรตหุ ้นทไมธรรมดาเพยงแค่ 6 ปีของการเข ้า ี ี ์ ี่ ่ ี ั ิ วงการ “สนติ สงหวังชา” สามารถสร ้างผลตอบแทนได ้แล ้วกว่า 27 เท่าตัว ด ้วยแนวคิดทีเรียบง่าย ลุมลึก สุขมใจเย็น จนได ้รับรางวลผู ้ถอ ่ ่ ุ ั ื ิ ั ื่ ั หุ ้นคณภาพมาแล ้ว เชญพบกับทายาทสงกัดมวยชอดังผู ้ได ้รับชยชนะ ุ ั ี ั ิ บนสงเวยนหุ ้นของ “สนต ิ สงหวงชา” ั ความเคลือนไหวในรอบปี ่ ื้ ก็ปรับพอรตหุ ้นตลอดเวลา โดยการขายออกและซอเข ้าจํานวนเทาๆ กน ์ ่ ั ึ่ ื้ เพราะโดยปกตแล ้วผมจะไมถอเงนสด ซงถ ้าอยากจะซอหุ ้นก็ต ้องขาย ิ ่ ื ิ ื้ ื้ ตัวอืนเพือเอาเงินมาซอ ไม่มแบบทีวาขายแล ้วเก็บเงินสดๆ ไว ้รอซอหุ ้น ่ ่ ี ่ ่ อย่างนีไม่ม ี ้ ด ัชน ี 400 จด ขายขาดทน? ุ ุ โดย ปกติผมเล่นหุ ้นจะไม่ดต ้นทุนตัวเอง ไม่เคยรู ้ว่าตัวเองมีต ้นทุน ู ิ ่ ู เทาไหร่ จะวัดผลงานของตัวเองโดยจะดูวาต ้นปี มลค่าสนทรัพย์รวมมี ่ เทาไหร่ และปั จจุบันมีเท่าไหร่ โดยจะแทร็คทุกๆ ปี พูดง่ายๆก็คอดูเป็ น ่ ื พอรตรวม ไม่ได ้มานั่งดูต ้นทุนราคาเป็ นรายตัวว่าขายไปขาดทุนหรือ ์ กําไร แตถ ้าหากไปมองตัวเลขจรงๆ ก็มทังขาดทนทงกําไรผสมกน ่ ิ ี ้ ุ ั้ ั ่ แล ้วแต่ชวง ่ มองแคสวนตาง ่ ่ ื้ ทไมมาสนใจต ้นทนราคาเป็นรายตัวเพราะความสําคัญในการซอหุ ้นมัน ี่ ่ ุ ื้ อยูทวา หุ ้นตัวนันๆ ราคาจะขนได ้อกเทาไหร่ แต่ราคาทีเราซอมาไม่ได ้มี ่ ี่ ่ ้ ึ้ ี ่ ่ ้ ความสําคัญอะไรเลย...
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...Introduction to E-business To Debbie and Richard Introduction to E-business Management and strategy Colin Combe AMSTERDAM BOSTON HEIDELBERG LONDON NEW YORK PARIS SAN DIEGO SAN FRANCISCO SINGAPORE SYDNEY Butterworth-Heinemann is an imprint of Elsevier OXFORD TOKYO Butterworth-Heinemann is an imprint of Elsevier Linacre House, Jordan Hill, Oxford OX2 8DP 30 Corporate Drive, Suite 400, Burlington, MA 01803 First edition 2006 Copyright ß 2006, Elsevier Ltd. All rights reserved No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone: (þ44) (0) 1865 843830; fax: (þ44) (0) 1865 853333; email: permissions@elsevier.com. Alternatively you can submit your request online by visiting the Elsevier website at http://www.elsevier.com/locate/ permissions, and selecting Obtaining permission to use Elsevier material British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloguing in Publication Data Control Number: 2005938727 ISBN–13: 978-0-7506-6731-9 ISBN–10: 0-7506-6731-1 For information on all Butterworth-Heinemann publications visit our website at http:/ /books.elsevier.com Printed and bound in...
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