CHAPTER 4: A TOUR OF THE CELL I. CELLS ARE THE SMALLEST UNITS OF LIFE A. The study of cells began with the microscope. • Robert Hooke was the first to describe cells in 1665. • Micrographs are photos taken with microscopes • Light microscope (LM) has magnification up to 1000x o For viewing living cells • Electron microscope (EM) has magnification up to 1,000,000x o Scanning EM (SEM) for viewing surface features o Transmission EM (TEM) for viewing internal structures [pic][pic][pic] B. Why are cells small? • A cell’s surface area-to-volume ratio limits its size • Volume increases faster than Surface Area • Larger cells do not have enough Surface Area to support their Volume • Organisms get larger by becoming multicellular [pic] C. There are two major categories of cells. [pic] D. All cells are surrounded by a plasma membrane. • Prokaryotic AND eukaryotic cells are surrounded by a plasma membrane • Eukaryotic cells also have internal membranes • All membranes act as selective barriers • All membranes are built from proteins and phospholipids • Form phospholipid bilayer when exposed to water o Hydrophilic on outside, hydrophobic on inside • Membranes are described by the fluid mosaic model o Fluid because they have the consistency of salad oil o Mosaics because of the diversity of proteins they contain [pic] [pic] II. PROKARYOTIC CELLS ARE SMALLER AND SIMPLER. A. All prokaryotic cells are unicellular organisms. • All prokaryotes have a plasma membrane, nucleoid, and ribosomes. o Plasma membrane