...Nephropathic Infantile Cystinosis Introduction Nephropathic cystinosis is an atypical genetic lysomal storage disorder distinguished by a destruction of the transfer of amino acid cystine from the lysosomes. Lysosomes are responsible for breaking down unwanted materials into cellular substances, and when cystine accumulates it crystallizes in the lysosomes of the cells and progresses to harm multiple tissues and organs of the body. The intent of this paper is to inform the importance of taking medication to reduce the surplus of cystine into the body’s system. Recognizing signs and symptoms and properly diagnosing is a key factor in treating this disorder. Individuals with infantile cystinosis experience both tubular dysfunction (renal Fanconi syndrome) and glomeralular deterioration. The renal Fanconi Syndrome usually occurs within the first year of life. Glomeralular deterioration progresses throughout the first decade of life, resulting in end-stage renal failure unless patients are treated with cysteamine (The importance of early diagnosis of nephropathic cystinosis to limit tissue and organ damage by treating it with specific medication, and if left untreated patient can develop renal failure by the age of 10. The prevalence of the infantile form of cystinosis transpires in 1 in 100,000 – 200,000 live births and in the North American population there is a carrier frequency of 1 in every 200. Europeans from the United Kingdom...
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... | | | | | | | |Abstract: - Multiple perspectives are particularly appropriate for risk analysis. The Bhopal chemical accident of December 2-3, | |1984, is viewed here using this concept. The preceding paper has described the events surrounding the catastrophic leak | |of methyl isocyanate at the Union Carbide plant; it is considered a technical perspective on the accident. | Risk Analysis Physical hazards have always been a feature of life. In man’s early days there were natural hazards such as earthquakes, weather, and other living organisms (microbes, animals, and fellow human beings). In modem times hazards are increasingly manmade fire, explosions, chemical spills, drugs, pollution, radioactive material, etc. Analysis of hazards has traditionally involved engineers and scientists who have produced fault trees, mean time between...
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...Bhopal disaster Co o r din at es: 2 3 °1 6 ′ 5 1 ″ N 7 7 °2 4 ′ 3 8 ″ E From Wikipedia, the free encyclopedia The Bhopal dis as te r (commonly referred to as Bhopal gas trage dy) was a gas leak incident in India, considered one of the world's worst industrial catastrophes.[1] It occurred on the night of December 2–3, 1984 at the Union Carbide India Limited (UCIL) pesticide plant in Bhopal, Madhya Pradesh, India. A leak of methyl isocyanate gas and other chemicals from the plant resulted in the exposure of hundreds of thousands of people. The toxic substance made its way in and around the shantytowns located near the plant.[2] Estimates vary on the death toll. The official immediate death toll was 2,259 and the government of Madhya Pradesh has confirmed a total of 3,787 deaths related to the gas release.[3] Others estimate 3,000 died within weeks and another 8,000 have since died from gas- related diseases.[4][5] A government affidavit in 2006 stated the leak caused 558,125 injuries including 38,478 temporary partial and approximately 3,900 severely and permanently disabling injuries.[6] UCIL was the Indian subsidiary of Union Carbide Corporation (UCC), with Indian Government controlled banks and the Indian public holding a 49.1 percent stake. In 1994, the Supreme Court of India allowed UCC to sell its 50.9 percent share. Union Carbide sold UCIL, the Bhopal plant operator, to Eveready Industries India Limited in 1994. The Bhopal plant was later sold to McLeod...
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...A kid with Hepatitis A can return to school 1 week within the onset of jaundice. 2. After a patient has dialysis they may have a slight fever...this is normal due to the fact that the dialysis solution is warmed by the machine. 3. Hyperkalemia presents on an EKG as tall peaked T-waves 4. The antidote for Mag Sulfate toxicity is ---Calcium Gluconate 5. Impetigo is a CONTAGEOUS skin disorder and the person needs to wash ALL linens and dishes seperate from the family. They also need to wash their hands frequently and avoid contact. positive sweat test. indicative of cystic fibrosis 1. Herbs: Black Cohosh is used to treat menopausal symptoms. When taken with an antihypertensive, it may cause hypotension. Licorice can increase potassium loss and may cause dig toxicity. 2. With acute appendicitis, expect to see pain first then nausea and vomiting. With gastroenitis, you will see nausea and vomiting first then pain. 3. If a patient is allergic to latex, they should avoid apricots, cherries, grapes, kiwi, passion fruit, bananas, avocados, chestnuts, tomatoes and peaches. 4. Do not elevate the stump after an AKA after the first 24 hours, as this may cause flexion contracture. 5. Beta Blockers and ACEI are less effective in African Americans than Caucasians. 1. for the myelogram postop positions. water based dye (lighter) bed elevated. oil based dye heavier bed flat. 2.autonomic dysreflexia- elevated bed first....then check foley...
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