...EFSA Scientific Report (2009) 231, 1-107 SCIENTIFIC COOPERATION AND ASSISTANCE SCIENTIFIC REPORT OF EFSA Review of the potential health impact of β-casomorphins and related peptides 1 Report of the DATEX Working Group on β-casomorphins (Question N° EFSA-Q-2008-379) Issued on 29 January 2009 WORKING GROUP MEMBERS Ivano De Noni, Richard J. FitzGerald, Hannu J. T. Korhonen, Yves Le Roux, Chris T. Livesey, Inga Thorsdottir, Daniel Tomé, Renger Witkamp. 1 For citation purposes: Scientific Report of EFSA prepared by a DATEX Working Group on the potential health impact of β-casomorphins and related peptides. EFSA Scientific Report (2009) 231, 1-107 © European Food Safety Authority, 2009 Review of the potential health impact of β-casomorphins and related peptides SUMMARY Proteins are a very diverse family of large organic compounds involved in many important biological processes. Following their enzymatic hydrolysis during food processing or digestion, proteins may release fragments from their primary amino acid sequence. These fragments are called peptides, and many of them are known to be physiologically active. The possible beneficial effects of bioactive peptides have attracted increasing interest in recent years. On the other hand, there are also reports suggesting that some food-derived peptides might adversely affect human health. Among these, β-casomorphin-7 (BCM7), a peptide sequence present in the milk protein β-casein, has been suggested to...
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...CN3108: CHEMICAL ENGINEERING PROCESS LAB II Experiment B1 Adsorption for Protein Isolation (L) Frederick Chan Yew Meng U065963A (E) Gan Yue Sern U065873B (A) Giam Ming Yao Joshua U065944X (R) Farhana Mehnas D/O Haja N U065763H Group: M4 Submitted On: 13th October 2008 Contents Sections Page Summary 1 I Introduction 2 II Theoretical Background 3 III Experimental procedures 6 IV Results and Analysis 8 V Discussion 22 VI Conclusion 28 VII References 28 Summary This experiment was to determine the adsorption isotherm for bovine serum albumin (BSA) on an anion-exchange adsorption resin with a model that is derived from the experimental data and to draw a breakthrough curve for BSA for different superficial velocities and find out the controlling step occurring within the packed bed. The Freundlich Isotherm q=αC1v was then found to be a better model to approximate the adsorption isotherm for BSA as compared to Langmuir Isotherm. From the experimental data, the static capacity determined from Langmuir Isotherm approximation was estimated to be 330.033mg/g and the dynamic capacities flow rates of 5.0, 2.5, 0.5 ml/min were 0.918, 1.431 and 2.066 mg/g respectively, thus agreeing with theoretical knowledge that the static capacities should be larger than dynamic capacities as sufficient time were allowed for equilibrium...
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...3-L batch fermentation 9 4.8 Dry cell weight 9 4.9 Protein content 10 4.10 Lipid content 10 4.11 Protein digestibility 11 4. Discussion 12 5.12 Biomass production 12 5.13 Protein and lipid content 12 5.14 Protein digestibility 13 5. Conclusion 15 Reference iii Appendix ix ACKNOWLEDGEMENT At first, I would like to express the deepest gratitude to my supervisors, Dr. Hoang Tung, who always gave the valuable instructions, and encouraged me to achieve the best from my working during the research time. I also thank Mr. Phan Cong Hoang for helpful discussions during the preparation of this thesis report and for providing the bacterial strains. In addition, I owe a debt of thanks to the lab technician of Applied Hydrobiology Lab - International University, Ms. Vo Thi Minh Thu for offering me the best working condition during my research. The friendship of Nguyen Bang Phuong, Nguyen Nhat Thai and Tran The Vinh is much appreciated and has led to many interesting memories during my working. I also would like to thank to my coworkers, the undergraduate...
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... April 2012 Table of Contents 1.0 The Immune System 3 2.0 Antibodies 6 3.0 Avian Antibodies 7 4.0 Why IGY? 8 5 .0 Polyclonal Versus Monoclonal Antibodies………………………………………………………..9 6.0 Purpose of IGY Inc. – Antibody Extraction 10 7.0 IGY for Use in Humans ………………..………………………………………………………….11 8.0 References 15 IGY Immune Technologies & Life Sciences Inc. 1.0 The Immune System The human immune system is comprised of a complex network of lymphoid organs and highly specialized cells that protect the body against infection by recognizing and killing pathogens. This immune system includes lymphatic organs and vessels, lymph nodes, white blood cells, specialized cells and serum factors. The immune system utilizes both the lymphatic vessels and the blood circulatory system to transport white blood cells called lymphocytes through out the body (1). The immune system can be classified as an innate or adaptive system. As a first line of defense against pathogens, we depend on innate immunity. Innate immunity is nonspecific and includes physical barriers such as skin, mucous membranes and secretions with antimicrobial activity including tears and mucous. Pathogens that cross this line of defense are often destroyed by phagocytes which are white blood cells that engulf and digest cellular debris and foreign agents by the process known as phagocytosis. However, innate immunity is not sufficient to ward off all...
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...INSTRUCTOR GUIDE Human Anatomy & Physiology Laboratory Manual MAIN VERSION, Eighth Edition Update CAT VERSION, Ninth Edition Update FETAL PIG VERSION, Ninth Edition Update ELAINE N. MARIEB, R.N., Ph.D Holyoke Community College SUSAN T. BAXLEY, M.A. Troy University, Montgomery Campus NANCY G. KINCAID, Ph.D Troy University, Montgomery Campus PhysioEx™ Exercises authored by Peter Z. Zao, North Idaho College Timothy Stabler, Indiana University Northwest Lori Smith, American River College Greta Peterson, Middlesex Community College Andrew Lokuta, University of Wisconsin—Madison San Francisco • Boston • New York Cape Town • Hong Kong • London • Madrid • Mexico City Montreal • Munich • Paris • Singapore • Sydney • Tokyo • Toronto Editor-in-Chief: Serina Beauparlant Project Editor: Sabrina Larson PhysioEx Project Editor: Erik Fortier Editorial Assistant: Nicole Graziano Managing Editor: Wendy Earl Production Editor: Leslie Austin Composition: Cecelia G. Morales Cover Design: Riezebos Holzbaur Design Group Senior Manufacturing Buyer: Stacey Weinberger Marketing Manager: Gordon Lee Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings, 1301 Sansome St., San Francisco, CA 94111. All rights reserved. Manufactured in the United States of America. This publication is protected by Copyright and permission should be obtained from the publisher prior to any prohibited reproduction, storage in a retrieval system, or transmission in any form or by any means...
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...Vol 450 | 20/27 December 2007 | doi:10.1038/nature06385 LETTERS Isolation of rare circulating tumour cells in cancer patients by microchip technology Sunitha Nagrath1*, Lecia V. Sequist2*, Shyamala Maheswaran2, Daphne W. Bell2{, Daniel Irimia1, Lindsey Ulkus2, Matthew R. Smith2, Eunice L. Kwak2, Subba Digumarthy2, Alona Muzikansky2, Paula Ryan2, Ulysses J. Balis1{, Ronald G. Tompkins1, Daniel A. Haber2 & Mehmet Toner1 Viable tumour-derived epithelial cells (circulating tumour cells or CTCs) have been identified in peripheral blood from cancer patients and are probably the origin of intractable metastatic disease1–4. Although extremely rare, CTCs represent a potential alternative to invasive biopsies as a source of tumour tissue for the detection, characterization and monitoring of non-haematologic cancers5–8. The ability to identify, isolate, propagate and molecularly characterize CTC subpopulations could further the discovery of cancer stem cell biomarkers and expand the understanding of the biology of metastasis. Current strategies for isolating CTCs are limited to complex analytic approaches that generate very low yield and purity9. Here we describe the development of a unique microfluidic platform (the ‘CTC-chip’) capable of efficient and selective separation of viable CTCs from peripheral whole blood samples, mediated by the interaction of target CTCs with antibody (EpCAM)-coated microposts under precisely controlled laminar flow conditions, and without requisite...
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...CONTENTS Title Page.no 1. Introduction To Nanoparticles (2) 2. Nanoparticulate systems For Targeting (13) 3. Drug Targeting (25) 4. Approaches To Drug Targeting (29) 5. Nanoparticle Drug Delivery Market (47) 6. Future Barriers And Challenges (48) 7. Various Nanopharmaceuticals And Their Case Studies (49) 8. NanoDrug Patenting (54) 9. Conclusion (57) 10. Bibliography (58) NANOPARTICLES IN DRUG TARGETING 1. INTRODUCTION NANOPARTICLES * Nanoparticles are in solid state and are either in amorphous or crystalline They include Nanocapsules and Nanospheres.They are able to adsorb or encapsulate a drug thus protecting it against chemical and enzymatic degradation...
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...teach the client? A) B) C) D) Clean the meatus, begin voiding, then catch urine stream Void a little, clean the meatus, then collect specimen Clean the meatus, then urinate into container Void continuously and catch some of the urine A: Clean the meatus, begin voiding, then catch urine stream. A clean catch urine is difficult to obtain and requires clear directions. Instructing the client to carefully clean the meatus, then void naturally with a steady stream prevents surface bacteria from contaminating the urine specimen. As starting and stopping flow can be difficult, once the client begins voiding it’s best to just slip the container into the stream. Other responses do not reflect correct technique 3. Following change-of-shift report on an orthopedic unit, which client should the nurse see first? A) B) C) D) 16 year-old who had an open reduction of a fractured wrist 10 hours ago 20 year-old in skeletal traction for 2 weeks since a motor cycle accident 72 year-old recovering from surgery after a hip replacement 2 hours ago 75 year-old who is in skin traction prior to planned hip pinning surgery. C: Look for the client who has the most imminent risks and acute vulnerability. The client who returned from surgery 2 hours ago is at risk for life threatening hemorrhage and...
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...FOODS YOU SHOULD NEVER EAT Foods that Make You Fat and Destroy Your Health Page | 1 Copyright ©2010 Eat Healthy Secrets ISBN XXXXXXXX All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, recording, or otherwise, without the prior written permission of the author. Printed in the United States of America Page | 2 Table of Contents INTRODUCTION ..............................................................................................................5 THE DANGER OF PROCESSED FOODS ......................................................................8 REFINED SUGAR IS POISON ......................................................................................12 THE TRUTH ABOUT FAT .............................................................................................27 WHY YOU SHOULD AVOID HIGH FRUCTOSE CORN SYRUP ..................................32 WATCH OUT FOR ASPARTAME .................................................................................40 AVOID MONOSODIUM GLUTAMATE ..........................................................................55 OTHER FOOD ADDITIVES YOU SHOULD AVOID ......................................................62 THE PROBLEM WITH BREAKFAST CEREALS ..........................................................73 THE PROBLEM WITH DIET SODAS ......................................................................
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...Revista Mexicana de Ingeniería Química Vol. 13, No. CONTENIDO 3 (2014) 765-778 Volumen 8, número 3, 2009 / Volume 8, number 3, 2009 OPTIMIZATION OF ENZYMATIC SACCHARIFICATION OF WHEAT STRAW IN A MICRO-SCALE SYSTEM BY RESPONSE SURFACE METHODOLOGY ´ 213 Derivation and application of the Stefan-Maxwell equations ´ ´ OPTIMIZACION DE LA SACARIFICACION ENZIMATICA DE PAJA DE TRIGO EN ´ ´ (Desarrollo y aplicación las ecuaciones de Stefan-Maxwell) MICROESCALA A TRAVESdeDE LA METODOLOGIA DE SUPERFICIE DE Stephen Whitaker RESPUESTA C. Molina1∗ , A. S´ nchez2 , A. Seraf´n-Mu˜ oz3 y J. Folch-Mallol4 a ı n de Guanajuato - Guanajuato, Depto. de Ingenier´a Qu´mica, Noria Alta s/n, 36050 Guanajuato, ı ı 245 Modelado de la biodegradaciónGto., M´ xico. lodos de hidrocarburos totales del petróleo en biorreactores de e 2 Centro de Investigaci´ n y de Estudios Avanzados del IPN, Unidad de Ingenier´a Avanzada. Av. del Bosque 1145, o intemperizados en suelos y sedimentos ı Colonia el Baj´o, Zapopan, 45019, Jalisco, M´ xico. ı e (Biodegradation modeling of sludge bioreactors of total petroleum hydrocarbons weathering in soil 3 Universidad de Guanajuato - Guanajuato, Depto. de Ingenier´a Ambiental, Av. Ju´ rez 77, Zona Centro, 36000, ı a and sediments) Guanajuato, Gto., M´ xico. e S.A. Medina-Moreno, S. Huerta-Ochoa, L. 4 Universidad Aut´ noma del Estado de Morelos, CentroC.A. Lucho-Constantino, enAguilera-Vázquez,ıA. Jiménezo de Investigaci´ n Biotecnolog´a,...
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...Maria Vasilenko 223901 Feasibility of using biosensors for heavy metal detection in complex matrices such as bio-slurries. Master of Science Thesis Examiners: Professor Matti Karp Professor Raghida Lepistö Examiner and topic approved in The Science and Bioengineering Department Council meeting on 7.11.2012 Abstract TAMPERE UNIVERSITY OF TECHNOLOGY Master‟s Degree Programme in Science and Bioengineering Vasilenko Maria: Feasibility of using biosensors for heavy metal detection in complex matrices such as bio-slurries. Seminar paper, 97 pages November 2012 Major: Biotechnology Examiners: Matti Karp, Raghida Lepisto Keywords: environmental pollution, heavy metals, biosensors, slurries The quality of bioslurries that are used in industrial production and agriculture need to be watched very closely to avoid spreading of contaminants on area and poisoning of humans and animals. Because heavy metals are very stable and toxic in many chemical compositions, their amount should be estimated very thoroughly. A new approach that involved biosensors was tested in this study. Because the slurries are complex non-unified matrices which composed of two phases – solid and liquid, the cell behavior can varies a lot from the one that explained in water and so the estimation of ion concentration can be not reliable. It was shown that the cell actually behave different in the slurries. Normally the dissolved compounds suppress the biosensor activity and, in the same time, the ions in the...
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...Journal of Controlled Release 113 (2006) 189 – 207 www.elsevier.com/locate/jconrel Review Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective D. Venkat Ratnam, D.D. Ankola, V. Bhardwaj, D.K. Sahana, M.N.V. Ravi Kumar ⁎ Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Phase-X, S.A.S. Nagar, Mohali, Punjab, India - 160062 Received 31 January 2006; accepted 26 April 2006 Available online 13 May 2006 Abstract Antioxidants are emerging as prophylactic and therapeutic agents. These are the agents, which scavenge free radicals otherwise reactive oxygen species and prevent the damage caused by them. Free radicals have been associated with pathogenesis of various disorders like cancer, diabetes, cardiovascular diseases, autoimmune diseases, neurodegenerative disorders and are implicated in aging. Several antioxidants like SOD, CAT, epigallocatechin-3-O-gallate, lycopene, ellagic acid, coenzyme Q10, indole-3-carbinol, genistein, quercetin, vitamin C and vitamin E have been found to be pharmacologically active as prophylactic and therapeutic agents for above mentioned diseases. Antioxidants are part of diet but their bioavailability through dietary supplementation depends on several factors. This major drawback of dietary agents may be due to one or many of the several factors like poor solubility, inefficient permeability, instability due to storage of food, first pass effect and GI degradation. Conventional...
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...NINTH EDITION Burton’s MICROBIOLOGY FOR THE HEALTH SCIENCES Paul G. Engelkirk, PhD, MT(ASCP), SM(AAM) Biomedical Educational Services (Biomed Ed) Belton, Texas Adjunct Faculty, Biology Department Temple College, Temple, TX Janet Duben-Engelkirk, EdD, MT(ASCP) Biomedical Educational Services (Biomed Ed) Belton, Texas Adjunct Faculty, Biotechnology Department Temple College, Temple, TX Acquisitions Editor: David B. Troy Product Manager: John Larkin Managing Editor: Laura S. Horowitz, Hearthside Publishing Services Marketing Manager: Allison Powell Designer: Steve Druding Compositor: Maryland Composition/Absolute Service Inc. Ninth Edition Copyright © 2011 Lippincott Williams & Wilkins, a Wolters Kluwer business © 2007 Lippincott Williams & Wilkins, © 2004 Lippincott Williams & Wilkins, © 2000 Lippincott Williams & Wilkins, © 1996 Lippincott-Raven, © 1992, 1988, 1983, 1979 JB Lippincott Co. 351 West Camden Street Baltimore, MD 21201 Printed in the People’s Republic of China All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees...
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...No. Nama Perguruan Tinggi AKADEMI AKUNTANSI PGRI JEMBER Nama Pengusul Sisda Rizqi Rindang Sari Program Kegiatan Judul Kegiatan 1 PKMK KUE TART CAENIS ( CANTIK, ENAK DAN EKONOMIS) BERBAHAN DASAR TAPE 2 AKADEMI FARMASI KEBANGSAAN Nensi MAKASSAR AKADEMI KEBIDANAN CITRA MEDIKA SURAKARTA AKADEMI KEBIDANAN GIRI SATRIA HUSADA AKADEMI KEPERAWATAN KERTA CENDIKA SIDOARJO AKADEMI KEPERAWATAN KERTA CENDIKA SIDOARJO AKADEMI KEPERAWATAN KERTA CENDIKA SIDOARJO Putri Purnamasari PKMK LILIN SEHAT AROMA KURINDU PANCAKE GARCINIA MANGOSTANA ( PANCAKE KULIT MANGGIS ) 3 PKMK 4 Latifah Sulistyowati PKMK Pemanfaatan Potensi Jambu Mete secara Terpadu dan Pengolahannya sebagai Abon Karmelin (Karamel Bromelin) : Pelunak Aneka Jenis Daging Dari Limbah Nanas Yang Ramah Lingkungan, Higienis Dan Praktis PUDING“BALECI”( KERES) MAKANAN BERSERATANTI ASAM URAT 5 Achmad PKMK Zainunddin Zulfi 6 Dian Kartika Sari PKMK 7 Radita Sandia PKMK Selonot Sehat (S2) Diit untuk Penderita Diabetes 8 AKADEMI PEREKAM Agustina MEDIK & INFO KES Wulandari CITRA MEDIKA AKADEMI PEREKAM MEDIK & INFO KES Anton Sulistya CITRA MEDIKA AKADEMI PEREKAM Eka Mariyana MEDIK & INFO KES Safitri CITRA MEDIKA AKADEMI PEREKAM MEDIK & INFO KES Ferlina Hastuti CITRA MEDIKA AKADEMI PEREKAM Nindita Rin MEDIK & INFO KES Prasetyo D CITRA MEDIKA AKADEMI PEREKAM MEDIK & INFO KES Sri Rahayu CITRA MEDIKA AKADEMI PERIKANAN YOGYAKARTA PKMK Kasubi Wingko Kaya Akan Karbohidrat...
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