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Chapter 7

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IB HL Topic 7
Nucleic Acids
Homework Assignments

Topic 7.1 DNA Structure and Replication

Watch these videos first: (most are very short)
DNA packaging by HHMI: http://www.hhmi.org/biointeractive/dna-packaging
DNA replication by Bozeman: https://www.youtube.com/watch?v=FBmO_rmXxIw

Outline the structure of nucleosomes. State the function of nucleosomes. Describe how DNA structure suggests its mechanism of replication. Identify the direction in which DNA polymerases add new nucleotides to a growing DNA molecule. Identify two purposes for regions of the DNA that do not code for proteins. Name the two scientists that investigated the structure of DNA using X-ray diffraction. Name the two scientists that finally proved DNA is the genetic material and briefly describe their experiment. Explain the process of DNA replication on both the leading and lagging strand. Be sure to include the following enzymes: helicase, DNA gyrase, single strand binding protein, DNA primase, DNA poly I, and DNA poly III.

Topic 7.2
Transcription and gene expression

Watch these videos first:
Transcription by ndsuvirtualcell: https://www.youtube.com/watch?v=WsofH466lqk mRNA processing by ndsuvirtualcell: https://www.youtube.com/watch?v=YjWuVrzvZYA mRNA splicing by ndsuvirtualcell: https://www.youtube.com/watch?v=FVuAwBGw_pQ epigenetics by Bozeman: https://www.youtube.com/watch?v=i9a-ru2ES6Y

Describe the direction of the transcription process. Describe how nucleosomes help regulate transcription in eukaryotes. Describe how splicing of mRNA increases the number of different proteins an organism can produce. Explain how DNA methylation can affect gene expression. Explain the process of transcription.

Topic 7.3
DNA Translation

Watch this video first:
Translation by HHMI:

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