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Christian Nation

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Submitted By gmk1223
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Garrett Kelly
Dr. Tushup
7/17/13
Nancy C. Andreasen is an expert on psychiatric disorders and most importantly an expert on schizophrenia. In earlier years the symptoms of schizophrenia were thought to be in a single brain region. However, with more experts and more studies taking place on schizophrenia we are finding out that there are many areas in the brain that are affected by schizophrenia. Based on empirical data derived from both magnetic resonance and positron emission tomography, we have developed a model that implicates connectivity among nodes located in prefrontal regions, the thalamic nuclei, and the cerebellum(Andreasen, 1998). If there is a disruption in this circuitry it will produce cognitive dysmetria, which will lead to difficulty in prioritizing, processing, coordinating and responding to information. The study of neural mechanisms of schizophrenia has passed through three phases during the past several decades. The first phase was used to demonstrate that schizophrenia was a brain disease. This phase was supported primarily through the use of neuro-imaging techniques such as computerized tomography, which consistently showed that patients had diffuse nonspecific abnormalities such as prominent sulci or ventricular enlargement(Andreasen 1982,1990). The second phase drew on traditions of neurology and neuropsychology, it attempted to localize the anatomic abnormalities and relate specific manifestations of the illness to specific brain regions (Andreasen 1986). Their were specific relationships that were hypothesized and partially verified include the prefrontal cortex and negative symptoms, the temporal lobes and auditory hallucinations, and the planum temporal and thought disorder. The third phase is relatively recent and draws on traditions of cognitive psychology, models of distributed parallel processing, and the study of neural

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