Chronic anaemia may result from the malnutrition in dominant EB in recessive forms of EB there is still research being conducted. The rate of anemia is normally higher in EB affected persons than non EB affected persons. There are many reasons the anemia occurs in the EB population. Iron deficiency and protein loss from unhealed wounds are main proponents. Blood transfusions are a tricky topic for this area as some populations may have an iron overload such as those predisposed to sickle cell anemia. Other complications include chronic blood loss from scarring resulting in reduced hemoglobin (Hwang, Shelley Ji Eun et al. 2015).Cardiomyopathy may result as a complication this is where the heart has has a difficult time pumping blood to your …show more content…
Contractures is the irregular development of muscles, tendons and tissues resulting in irregular joints. This occurs often in both recessive and dominant EB. In the dominant from feet and hands sometime look like mittens with almost not fingers or toes being recognizable. In the recessevice form it may be limited to some fingers and not all or partial fusion of fingers. There are 14 genes that help regulate growth, healing and proper function. However the main cause is that the body cannot heal itself, lesions and scarring often result in infections and these manifest in the form of many of these complications. Skin grafting has shown to be one more effective methods to help skin grow back but much is still unknown in the area of contractures(Marcelo S.,Pierina F.,Gustavo S. et al 2016).In adolescent and adult populations with recessive EB-HS and dominant type EB mucosal squamous cell carcinoma is more likely to develop. However, there are still researching SCC treatment methods due to the limited population to study; EB is a rare disease and contracting SCC falls within a even smaller subgroup.Some of the treatment methods currently used are amputation, chemotherapy, radiotherapy and surgery;the surgery of choice is wide local