...It had been a long year battling Breast Cancer, all the doctor appointments, chemotherapy and then the radiation therapy, Grannie was exhausted. She just wanted to sleep all day, she was worn out. The family was told that she would bounce back after a month or so, the radiation therapy would wear off, then she would be back to herself in no time, but that never happened. She had told us that she was going to the doctor that afternoon; he had called to ask her to come in. That is never a good thing. My aunt called and said that Grannie wanted a family meeting at seven that night, when my husband asked what was going on she just said “she just wants us all together so she can talk to us all at the same time. She doesn’t want to have to make a bunch of phone calls.” It was then, everyone knew it was not going to be good, but our first thought was the breast cancer had returned. Who would have ever imagined what she was about to tell us. The family was sitting in the living room and was in total shock when she explained that the doctors told her she had leukemia. They did not know when she contracted it; there was no way of knowing how long she had it. She said they told her that she would need extensive chemotherapy and radiation treatments to battle the leukemia, but there were no guarantees that she could beat it. She sat there with tears running down her face when she said, “I am just too tired. I cannot fight this battle, I’m too weak. I’m sorry and I love you all, please know...
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...Abstract Gleevec is heralded as a savior drug for cancer research. Created by the rational drug design model, Gleevec targets the tyrosine kinase enzyme in CML patients.[10] By targeting and binding to the active sites of the cancerous cells, Gleevec denaturizes them, preventing the spread of the disease.[10] Gleevec has been FDA approved to be administered to patients diagnosed with chronic myelogenous leukemia and also patients with gastrointestinal stromal tumors.[6] Although, this treatment has also been proved to aid in other fields of medicine, ranging from treating other types of cancers to delaying tumor growth to therapy for diabetes and even to cancer treatment in pets.[5,6,8,9] However, for Gleevec to have been made other cell targeted drugs had to be made before it. And just as those drugs paved the way for Gleevec, Gleevec is paving the way for even more cancer treatments to be made. Introduction and Background The official war on cancer began when President Richard Nixon declared that this was the next big thing in the history of the United States. He compared the battle and potential cure of cancer to the process of landing on the moon. However, the battle against cancer has proved to be much more difficult. But there is progress being made. In 2003, 556,902 people in the United States died from cancer.[11] However, in 2002, 557,271 people in the United States died from cancer.[11] Even though the difference of deaths was not that great, this was still...
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...LYMPHOMA SOCIETY TAWANDA BRYANT 11410 COUNTY ROAD 20 BOLIGEE, AL 35443 (205) 336-9851 tbryant3030@yahoo.com LEADERSHIP and ORGANIZATIONAL MAR12 SEC AA March 9, 2012 INSTRUCTOR: SHAROLYN HERGOTT LEUKEMIA & LYMPHOMA SOCIETY I have picked this organization because my best friend passed away last year with leukemia and I wanted to find out more on this disease and what I can do to help. Been passionate and concern about not only her health but the health of her kids, my research will show why it is important to me as well as others. Having a passion for helping other in any way I can is what I am going for. I also like the face that I can somewhat relate to their illness and pain they endure within their life. I would love to find a quicker cure for these diseases, but I know others are working on something better. Having someone close to you with any type of disease, not just leukemia or lymphoma is hard to take in and understand. Having the ability to communicate, have critical thinking, collaboration, and the ability to problem solve is what I aim for. What I do will reflect on others within the society as well as patients and families. Raising money to help families who can’t get the medication needed, rides to and from their doctor appointments and everything they have to do is my goal at “Leukemia & Lymphoma Society”. If you care and can share the value and thrive to make a real impact, this is the time to make a difference in...
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...Classification of Human Acute Myeloid Leukemia & Acute Lymphoid Leukemia by Gene Expression Monitoring Affiliation: Edward Waters College By: Myschelle Jones Table of Contents Page 2-Table of Contents Page 3-Abstract Page 4-5-Introduction Page 6-Process of Distinguishing AML and ALL Page 7-Results Page 8-Conclusion Page 9-Discussion Pages 10-12-References Abstract Cancer classification using gene expression data is known to contain the keys for addressing the fundamental problems relating to cancer diagnosis and drug discovery. Cancer research is one of the major research areas in the medical field. Accurate prediction of different tumor types has great value in providing better treatment and toxicity minimization on the patients. Performing gene selection helps to reduce data size. More importantly, gene selection removes a large number of irrelevant genes, which improves the classification accuracy. Introduction Leukemia is a type of blood cancer that is “often fatal”.[1] The white blood cells displace normal blood, leading to infection, shortage of red blood cells anemia, bleeding, and other disorders. Certain types of childhood leukemia respond well to treatment, “which includes drugs, chemotherapy, and radiotherapy”. [2] There are two types of leukemia that will be discussed, acute lymphocytic leukemia and acute myelogenous leukemia. Acute lymphocytic leukemia is the most common “type of cancer in children”. [1] Acute...
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...Cancer is among the leading causes of deaths worldwide. It accounted for 7.4 million deaths (around 13% of all deaths) in 2004 (Felix, 2010). It is defined as the uncontrolled growth of abnormal cells in the body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor except in the case of leukemia where cancer prohibits normal blood function by abnormal cell division in the blood stream. In some cases cancer is preventable by avoidance of the risk factors, control occupational hazards, vaccination, etc. Unfortunately some cancers, like leukemia, are not preventable. Leukemia is commonly known as a cancer of the blood and affects blood-forming cells in the body. Leukemia is a type of cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream. These deranged, immature cells accumulate in the blood and within organs of the body and are not able to carry out the normal functions of blood cells. Each year, nearly 27,000 adults and more than 2,000 children in the United States learn that they have leukemia. From 1999–2006, the rate of people dying from leukemia has varied, depending on their race and ethnicity (Center for Disease Control and Prevention , 2010). It is estimated that each year...
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...is where blood cells are made.When you have leukemia, the bone marrow starts to make a lot of abnormal white blood cells, called leukemia cells. They don't work as the normal white blood cells should, they grow much quicker than normal cells, and they don't stop growing when they should. Over a period of time, leukemia cells will crowd out the normal blood cells. This can lead to serious health problems such as anemia (a condition that develops when your blood lacks enough healthy red blood cells or hemoglobin), bleeding, and infections. Leukemia cells can also spread to other organs and cause swelling or pain. There are many different types of leukemia including acute or chronic. The first type, acute leukemia gets worse quickly and may make you feel sick instantly whereas chronic leukemia gets worse and worse over time and may not cause symptoms for years. Other than being acute or chronic, leukemia can also be either lymphocytic or myelogenous. The four main types of leukemia are, Acute Myelogenous Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), and Chronic Lymphocytic Leukemia (CLL). The most common type of leukemia in children is Acute Lymphoblastic Leukemia. Lymphocytic leukemia affects white blood cells called lymphocytes. Myelogenous leukemia affects white blood cells called myelocytes. Experts are not exactly sure what causes leukemia, but there are definitely some potential risk factors. Some risk factors include, having...
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... Business & Company Resource Center ________________________________ Datamonitor Industry Market Research , Feb 13, 2012 pNA China - Healthcare Providers. Full Text: COPYRIGHT 2012 Datamonitor MarketDefinition The healthcare providers sector is valued as total expenditure on healthcare in each country. This includes final consumption spending on healthcare goods and services. Goods and services in this sector include inpatient, outpatient, long-term medical care, medical goods including pharmaceuticals and supplies, and collective services such as administration requirements. Public spending (e.g. by national and local governments, social security schemes) and private spending (e.g. payments made by private-sector health insurers and individual out-of-pocket expenditures) are both included. Any currency conversions used in the creation of this report have been calculated using constant 2010 annual average exchange rates. For the purposes of this report, Asia-Pacific comprises Australia, China, India, Indonesia, Japan, New Zealand, Singapore, South Korea, Taiwan, and Thailand. ResearchHighlights *The Chinese healthcare providers sector is expected to generate total revenue of $303.9 billion in 2011, representing a compound annual growth rate (CAGR) of 15.9% between 2007 and 2011. *The outpatient care segment is expected to be the sectors most lucrative in 2011, with total revenue of $106.4 billion, equivalent to 35% of the sector's overall...
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...* What Is a Blood Disorder? Bottom of Form Blood disorders are physical conditions that prevent the normal function of blood in the body. A disorder may involve factors that interfere with the production of the individual components found in the blood, such as hemoglobin or blood proteins. The nature of a blood disorder may also include situations where the blood does not coagulate properly, or the blood cells themselves are malformed or infected. There is a wide range of blood diseases known today. Anemia is one of the more common examples of a blood disorder. Sometimes referred to as tired blood, a person who is anemic is likely to have a lack of proteins and other elements in the blood. As a result, the blood cannot carry the needed nutrients to various parts of the body and the individual is likely to feel fatigued more often. Over time, anemia can also have a negative impact on the emotions, as the blood is unable to supply proper nutrition to the brain for the production of chemicals that help to maintain an even mood. Sickle cell anemia is one of the more serious types of anemic blood disorder. In addition to fatigue, a person suffering with this disorder is also likely to experience a great deal of pain. The pain may be localized in one part of the body or migrate to different areas throughout the course of the day. Ad Hemophilia is another relatively common blood disorder. Hemophiliacs suffer with a condition in which the blood lacks the normal ability to coagulate...
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...return that reflects outstanding performance and to adequately reward those who invest ideas and work in our company. 4 | GROUP REVIEW 19 | H E A LT H C A R E P O R T F O L I O 57 | C O R P O R AT E C I T I Z E N S H I P 8 5 | C O R P O R AT E G O V E R N A N C E 111 | C O M P E N S AT I O N R E P O R T 1 31 | F I N A N C I A L R E P O R T 1 2 N OVART I S G R OU P AN N UA L R E PO R T 2 010 CONTENTS GROUP REVIEW Financial Highlights News in 2010 Letter from Daniel Vasella Interview with Joseph Jimenez 4 5 7 15 19 23 35 39 45 51 57 61 67 73 78 83 85 90 101 111 112 HEALTHCARE PORTFOLIO Contents Pharmaceuticals Novartis Institutes for BioMedical Research Vaccines and Diagnostics Sandoz Consumer Health CORPORATE CITIZENSHIP Contents Commitment to Patients Commitment to People and Communities Commitment to the Environment Commitment to Ethical Business Conduct Independent Assurance Report CORPORATE GOVERNANCE Contents Our Board of Directors Our Management COMPENSATION REPORT Contents Compensation Report NOVARTIS GROUP FINANCIAL REPORT Contents Operating and Financial Review Equity Strategy Novartis Group Consolidated Financial Statements Financial Statements of Novartis AG Annual Report Photography Key Dates 2011, Contact Information and Forward-Looking Statements 131 134 177 180 252 268 270 4 | GROUP REVIEW 19 | H E A LT H C A R E P O R T F O L I O 57 | C O R P O R AT E C I T I Z E N S H I P 8 5 | C O R P O R...
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...Examination Paper Semester I: Organizational Behaviour IIBM Institute of Business Management IIBM Institute of Business Management Semester-1 Examination Paper MM.100 Organizational Behaviour Section A: Objective Type (30 marks) This section consists of Multiple Choice & Short Notes type Questions. Answer all the questions. Part One carries 1 mark each & Part two carries 5 marks each. Part one: Multiple choices: 1. It is the degree to which a person identifies with a particular organization and its goals, & wishes to maintain membership in the organization a. Job involvement b. Terminal value c. Attitude d. Value a. Job involvement 2. _________ means moving information from the hidden area to the open area a. blind area b. unknown area c. public area d. self disclosure d. self disclosure 3. An approach in which the goals of one party are in direct conflict with the goals of the other party a. Negotiation b. Distributive bargaining c. Stress d. None Ans. Negotiations 4. The measure of a person’s ability to operate within business organizations through social communication & interactions a. Transactional analysis b. Interpersonal skill c. Life position d. Johari window Ans. b. interpersonal skill 5. Where the source of power is in person’s control over rewarding outcomes, that power is called a. Coercive power b. Referent power c. Legitimate power d. Reward power Ans. d. Reward power Examination...
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...Harvard Law School Jean Monnet Chair Professor J.H.H. Weiler Harvard Jean Monnet Working Paper 1/01 Päivi Leino The European Central Bank and Legitimacy Is the ECB a Modification of or an Exception to the Principle of Democracy? Harvard Law School Cambridge, MA 02138 All rights reserved. No part of this paper may be reproduced in any form Without permission of the author. © Päivi Leino 2000 Harvard Law School Cambridge, MA 02138 USA The European Central Bank and Legitimacy Is the ECB a Modification of or an Exception to the Principle of Democracy? Päivi Leino, Åbo Akademi University( M.Pol.Sc. (international law), Åbo Akademi University, Finland; LL.M. candidate, London School of Economics and Political Science. This paper was concluded on August 8, 2000 and subsequent changes have not been considered. The author would like to thank Professor Markku Suksi and Lic.Pol.Sc. Kurt Långkvist for their comments and encouragement. The author has exclusive responsibility for all views, errors and omissions. Comments are invited to Paivi.Leino@abo.fi.) 1. The Sovereign of Monetary Policy The creation of a single market and the continuing concentration and integration at the European level have created phenomena that can neither be governed by nationally based policies nor left to the working of unregulated markets.( Hirst, Paul and Thompson, Grahame (1996), p. 156.) According to the European Court of Justice...
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...Bringing together creativity and literacy POSTED IN CREATIVE LITERACY We all know that literacy is the ability to read and write but the definition of creative is a little harder to define: it can be the ability to solve problems or being able to use your imagination. Bringing creativity and literacy together can be a powerful tool in teaching, writes Tonya Meers Creativity is characterised by originality and expressiveness, so it can mean making something or it can be something new and innovative. Sir Ken Robinson has said that “Creativity is about working in a highly focused way on ideas and projects, crafting them into their best forms and making critical judgements along the way.” Bringing creativity and literacy together can be a powerful tool in teaching. It allows children to be active in literacy, from acting out plays through characters that they’ve made themselves or through making props. It allows children to explore their imaginations. Getting involved in a story re-enforces the learning and can also teach practical skills, for example, working with templates or basic sewing. Children are naturally creative, if you stop and listen to them they often are natural storytellers. They love to make things up and will very often have imaginary worlds they will refer to. They also love to get involved in making things, giving them a sense of achievement. If they are engaged they will learn more, so it’s about harnessing their ability to soak up information...
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...சுப்பிரமணிய பாரதி சுப்பிரமணிய பாரதி (சின்னசுவாமி சுப்பிரமணிய பாரதி) (திசம்பர் 11, 1882 - செப்டம்பர் 11, 1921). இவர் பாரதியார் என்றும், மகாகவி என்றும் அழைக்கப்படுகிறார். பாரதி ஒரு கவிஞர், எழுத்தாளர், பத்திரிக்கையாசிரியர், விடுதலை வீரர், சமூக சீர்திருத்தவாதி என பல்வேறு பரிமாணங்கள் கொண்டவர். சுப்பிரமணியன் என்ற இயற்பெயர் கொண்டவர். தமிழின் கவிதை மற்றும் உரைநடையில் தன்னிகரற்ற புலமை பெற்ற பேரறிவாளரும், நவீன தமிழ் கவிதைக்கு முன்னோடியும் ஆவார் தம் எழுத்துக்களின் வாயிலாக மக்களின் மனதில் விடுதலை உணர்வை ஊட்டியவர். இந்திய வரலாற்றின் திருப்பங்கள் நிறைந்த காலகட்டத்தில் வாழ்ந்தவர். இவரின் சமகாலத்தைய மனிதர்கள் மகாத்மா காந்தி, பால கங்காதர திலகர், உ. வே. சாமிநாதையர், வ. உ. சிதம்பரம் பிள்ளை மற்றும் மகான் அரவிந்தர் ஆகியோர். தமிழ், தமிழர் நலன், இந்திய விடுதலை, பெண் விடுதலை, சாதி மறுப்பு மற்றும் பல்வேறு சமயங்கள் குறித்து கவிதைகளும் கட்டுரைகளும் எழுதியுள்ளார். இவருடைய கவித்திறனை மெச்சி பாரதி என்ற பட்டம் எட்டப்ப நாயக்கர்மன்னரால் எட்டயபுரம் அரசசபையால் வழங்கப்பட்டது. வாழ்க்கைக் குறிப்பு சின்னசாமி ஐயர் இலக்குமி அம்மாள் தம்பதியினருக்கு திசம்பர் 11 1882ல் தமிழ்நாட்டின் திருநெல்வேலி மாவட்டத்திலுள்ள எட்டயபுரத்தில் பாரதியார் பிறந்தார். இவரின் இயற்பெயர் சுப்பிரமணியன் என்பதாகும், எனினும் சுப்பையா என்று அழைக்கப்பட்டார். 1887ஆம் ஆண்டு இலக்குமி அம்மாள் மறைந்தார். அதனால் பாரதியார் பாட்டியான பாகீரதி அம்மாளிடம் வளர்ந்தார். தனது 11-ம் வயதில் பள்ளியில் படித்து வரும்பொழுதே கவிபுனையும் ஆற்றலை வெளிப்படுத்தினார். 1897 ஆம் ஆண்டு செல்லம்மாளை மணந்தார். 1898 ஆம் ஆண்டு தொழிலில் ஏற்பட்ட நட்டத்தினால் வறுமை...
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...1. Introduction This is the final project of the Course Named: Investment & Portfolio Analysis. The purpose of this project is to examine thoroughly if the CAPM holds true in the emerging capital market of Pakistan. Tests are conducted for a period of five years (2005-2009), which is characterized by intense return volatility (covering historically high returns over the examined period). 2.1. Karachi Stock Exchange * Incorporated on March 10, 1949 * Premier Stock exchange of the country * Started with 5 companies that had a paid up capital of Rs. 37 million. * Trading was done through an open-out-cry system * The first index was the KSE 50 Index * Exchange owned by 200 members * 652 companies listed * 4 indices * Modern Risk Management System a. Var Based Margin b. Pre Trade Margin Verification * KSE is FIX Compliant * Electronic Trading through KATS * Market capitalization*: US $ 26.04 billion * Publicly Listed Company with strategic investor * Products to include: a. Options b. ETFs c. Tradable Sector Indices d. Debt Market Trading * Broad based investor participation * Cross border listings of companies * Opening up of branches in other cities and in the region 2.2.1. Definition A stock exchange, share market or bourse is a corporation or mutual organization which provides facilities for stock brokers and trader s, to trade company stocks and other...
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...a wellestablished and invasive stem borer in Kenya. Among the isolates, Bt 44 and Bt 48 had the most potent endotoxin crystals to 1st instar C. partellus larvae. In addition, the efficacy of these two isolates was not statistically different (P>0.05) from that of Bta based on LT50 values. The findings show that these two locally available unidentified Bt isolates could be used in management of C. partellus and their characterisation (Cry protein) could aid in their utilization. Key words: Bt efficacy; Bt isolates; LT50; LC50; Introduction Maize (Zea mays L.) is the most important staple food crop in Kenya as well as in the subSahara Africa. However, farmers are yet to attain the potential yield per unit area due to a myriad of problems, major ones being infestation and damage by insect pests. Lepidopteran stem borers are generally considered as the most important...
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