...1. Introduction This assignment is a critique on the study published in The New England Journal of Medicine (NEJM) entitled ‘Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction’ by Bonaa et. al (2006) (also known as The NORVIT study). NEJM’s most recent impact factor was 51.296 (in 2006). NEJM boasts the largest paid circulation among medical journals, with close to 200,000 paying subscribers. It is printed weekly in the United States, Canada, the Netherlands, and Japan, and a range of translated articles reaches approximately 140,000 (New England Journal of Medicine.org, 2006). The NORVIT study was designed as a randomized, controlled, double-blind, intervention study. It included 3,749 men and women who had suffered and acute myocardial infarction within the last 7 days. The rationale behind the study was that high homocysteine levels are considered a risk factor for cardiovascular disease (Bonaa et al, 2006). The aim was to measure how effective lowering blood serum homocysteine levels with B vitamins was in preventing a secondary event. A collaborative meta-analysis published in The Journal of the American Medical Association, states that homocysteine levels are an independent predictor of ischemic heart disease and that studies on disease risk of genetic variants affecting homocysteine may help establish whether homocysteine is causally linked to vascular disease (2002: cited by Bonaa et al, 2006). The meta-analysis suggests that a large...
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...------------------------------------------------- KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY,KUMASI. ------------------------------------------------- ------------------------------------------------- COLLEGE OF HEALTH SCIENCES ------------------------------------------------- ------------------------------------------------- SCHOOL OF MEDICAL SCIENCES ------------------------------------------------- ------------------------------------------------- DEPARTMENT OF COMMUNITY HEALTH ------------------------------------------------- ------------------------------------------------- BIRTHWEIGHT OF NEWBORNS IN RELATION TO THE NUTRITIONAL STATUS OF PREGNANT WOMEN IN THE ATWIMA NWABIAGYA DISTRICT OF ASHANTI REGION OF GHANA. ------------------------------------------------- ------------------------------------------------- ------------------------------------------------- A DISSERTATION SUBMITTED TO THE SCHOOL OF GRADUATE STUDIES, ------------------------------------------------- KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY, KUMASI IN ------------------------------------------------- PARTIAL FULFILMENT OF REQUIREMENTS FOR THE AWARD OF MASTER OF ------------------------------------------------- PUBLIC HEALTH (MPH) DEGREE IN POPULATION AND REPRODUCTIVE HEALTH. ------------------------------------------------- ------------------------------------------------- ...
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...Virginia Medical School, Department of Psychiatry and Behavioral Sciences, 825 Fairfax Avenue, Norfolk, Virginia 23507; Phone: (757) 446-5888; Email: spiegedr@evms.edu KEY WORDS: Amnestic disorder, frontal lobe, diencephalic A Case of Probable Korsakoff’s Syndrome: A Syndrome of Frontal Lobe and Diencephalic Structural Pathogenesis and a Comparison with Medial Temporal Lobe Dementias by DAVID R. SPIEGEL, MD, and KHENG-JIM LIM, MD Drs. Spiegel and Lim are from the Department of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, Norfolk, Virginia. Innov Clin Neurosci. 2011;8(6):15–19 ABSTRACT Korsakoff’s Syndrome is an amnestic disorder that involves both anterograde and retrograde amnesia. Traditionally associated with longstanding alcohol misuse, thiamine deficiency has been long posited in its pathogenesis, as has dienecephalic lesions. Yet, through this case report, we highlight similarities (and differences) with medial temporal lobe memory disorders and the role of frontal lobe dysfunction in its retrograde amnesia. INTRODUCTION Wernicke’s encephalopathy (WE) and Korsakoff syndrome (KS) are generally viewed as two distinct stages of the same illness called Wernicke-Korsakoff syndrome (WK syndrome). WE, the acute form of the disease, consists of a degenerative brain disorder due to a thiamine deficiency (Vitamin B1), which is the same pathological state that can potentially lead to KS. This disease is typically seen in patients with chronic alcohol...
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...Unit 21: Nutrition for Health and Social Care Unit code: L/601/2407 QCF Level 3: BTEC Nationals Credit value: 10 Guided learning hours: 60 Aim and purpose This unit aims to give learners an understanding of current thinking on nutritional health particularly relating to users of health and social care services. Learners will then be able to apply this understanding and make recommendations to improve the nutritional health of an individual. Unit introduction This unit builds on learner understanding of the principles introduced in Unit 5: Fundamentals of Anatomy and Physiology for Health and Social Care. Improvements in the diet of individuals are increasingly being recognised as a significant factor in maintaining, or effecting improvements, in overall health. It is therefore important that people working in the health and social care sectors, or those who are responsible for the wellbeing of others, have a good understanding of nutrition and diet. This unit gives learners an understanding of nutrition from a science-based perspective and of the role that food plays in social contexts. The unit may also provide useful underpinning knowledge for the study of food hygiene and practical culinary skills. Learners will explore concepts of nutrition using the language of nutritional science. Different aspects of nutritional health will be defined and routine ways of measuring this explored. Other aspects of nutritional data will involve describing...
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...Ciaran Kelly, MD Celiac disease (CD) is an immune-mediated enteropathy secondary to permanent sensitivity to wheat gluten and related proteins in rye and barley. It results in characteristic histologic changes consisting of inflammation, crypt hyperplasia, and villous atrophy of the small intestine in genetically susceptible individuals. Significant variability in the clinical presentation of CD in the pediatric population complicates recognition of the disease in many patients. Treatment for CD consists of a lifelong strict gluten-free diet (GFD). Adherence to this diet is associated with resolution of most related signs and symptoms and a decreased risk of related complications. With an explosion of new knowledge over the span of two decades, our understanding of CD has changed dramatically. CD has gone from a rare condition causing gastrointestinal symptoms in children of European origin to a common disorder causing symptoms that affect multiple organ systems in all ages virtually worldwide.1 The overall prevalence of CD is similar in Europe and North America affecting up to 1% of the population.2,3 A large multicenter study in the United States, using serologic screening with biopsy confirmation to identify cases of CD, showed a prevalence of CD of 1:133 in individuals with no evident risk factors. Prevalence of CD in symptomatic patients was 1:56. The prevalence of diagnosed CD is much lower, especially in the United States. This reflects underrecognition...
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...Statistics and Computing Series Editors: J. Chambers D. Hand W. H¨ rdle a Statistics and Computing Brusco/Stahl: Branch and Bound Applications in Combinatorial Data Analysis Chambers: Software for Data Analysis: Programming with R Dalgaard: Introductory Statistics with R, 2nd ed. Gentle: Elements of Computational Statistics Gentle: Numerical Linear Algebra for Applications in Statistics Gentle: Random Number Generation and Monte Carlo Methods, 2nd ed. H¨ rdle/Klinke/Turlach: XploRe: An Interactive Statistical a Computing Environment H¨ rmann/Leydold/Derflinger: Automatic Nonuniform Random o Variate Generation Krause/Olson: The Basics of S-PLUS, 4th ed. Lange: Numerical Analysis for Statisticians Lemmon/Schafer: Developing Statistical Software in Fortran 95 Loader: Local Regression and Likelihood Marasinghe/Kennedy: SAS for Data Analysis: Intermediate Statistical Methods ´ Ruanaidh/Fitzgerald: Numerical Bayesian Methods Applied to O Signal Processing Pannatier: VARIOWIN: Software for Spatial Data Analysis in 2D Pinheiro/Bates: Mixed-Effects Models in S and S-PLUS Unwin/Theus/Hofmann: Graphics of Large Datasets: Visualizing a Million Venables/Ripley: Modern Applied Statistics with S, 4th ed. Venables/Ripley: S Programming Wilkinson: The Grammar of Graphics, 2nd ed. Peter Dalgaard Introductory Statistics with R Second Edition 123 Peter Dalgaard Department of Biostatistics University of Copenhagen Denmark p.dalgaard@biostat.ku.dk ISSN: 1431-8784 ISBN: 978-0-387-79053-4 DOI:...
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...Dear nutrition student, Thank you for inquiring about my RD/DTR study guide. And yes, there is no catch, the study guide is COMPLETELY FREE! All I ask for is some feedback. So feel free to shoot me any questions/comments! A little background: This study guide is the culmination of years of my own research. And after careful thought, I put into the study guide what I feel are the most important concepts you need to know for the RD/DTR exam. If you notice, I spent much time teaching you in detail the concepts you need to know, not just “spitting” you questions with little or no explanation. I believe this is important. I know you might be thinking “oh, how am I going to absorb and learn all this material?” I say, just read and answer the questions at your own pace. Simply test yourself and of course take some breaks along the way. Just take it one concept at a time. After you have mastered one concept, then move on to the next. I know if you study whole-heartedly what I have outlined in this study guide, you are sure to pass! GOOD LUCK! YOU CAN DO IT! ϑ Your nutrition friend, -Jonathan Brown, B.S, DTR THE “NO FLUFF” RD/DTR STUDY GUIDE *Updated as of July 2011 The “NO FLUFF” RD/DTR STUDY GUIDE Tips for taking the RD/DTR exam 1. PERIODICALLY CHECK THE CLOCK TO MAKE SURE YOU’RE GOOD ON TIME! If you wish, get a basic digital watch with a timer for...
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... UNIVERSITY OF CAPE COAST SCHOOL OF NURSING MSC. ADVANCED NURSING PRACTICE COURSE: ADVANCED CLINICAL PRACTICUM I AND II IN SPECIALTY AREA COURSE CODE: NUR 822S and NUR 829S PATIENT / FAMILY CASE STUDY (A NURSING PROCESS APPROACH) ON A CLIENT WITH GESTATIONAL TROPHOBLASTIC NEOPLASM BY: CHARLOTTE LAMPTEY SN/ADN/15/0030 AUGUST, 2016 CONTENTS * PREFACE * ACKNOWLEDGEMENT * INTRODUCTION CHAPTER ONE: OVERVIEW OF CLIENT SITUATION I. Literature review of gestational trophoblastic neoplasm CHAPTER TWO: COMPREHENSIVE HOLISTIC ASSESSMENT OF PATIENT/FAMILY I. Patient’s medical and personal history including review of the systems II.Physical examination III.Diagnostic evaluation IV.Nutritional assessment V. Psychosocial history VI. Patient developmental assessment VII.Spiritual assessment VIII.Quality of life assessment IX.Admission of patient CHAPTER THREE: ANALYSIS OF DATA CHAPTER FOUR: COLLABORATIVE PLAN OF CARE I. Presumptive medical diagnosis II.Nursing diagnosis III.Evidence-based interventions IV.Additional diagnostic procedures warranted but not done Medication to be ordered CHAPTER FIVE: DISCHARGE PLAN I. Community service and resource needed II.Client education plan III.Plans for follow-up of care CHAPTER SIX: EVALUATION PLAN Termination of care * SUMMARY * CONCLUSION * REFERENCE PREFACE The patient / family care study is an essential...
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...Natio onal Food d Policy P Plan of A Action an nd Count try Invest tment Pl lan Mon nitorin ng Repo ort 201 12 Ju uly 2012 FPMU, Food Div vision Ministry o M of Food an nd Disast ter Manag gement Gover rnment o of the Peo ople’s Rep public of Banglade esh This document is the result of a joint effort by the: Ministry of Agriculture Ministry of Finance (Finance Division and Economic Relations Division) Ministry of Fisheries and Livestock Ministry of Food and Disaster Management (Food Division and DMR Division) Ministry of Health and Family Welfare Ministry of Industries Ministry of Local Government, Rural Development and Cooperatives (LG Division and RDC Division) Ministry of Planning (Planning Division, Statistics and Informatics Division and IMED) Ministry of Primary and Mass Education Ministry of Social Welfare Ministry of Water Resources Ministry of Women and Children’s Affairs Coordinated by the FPMU, Food Division Ministry of Food and Disaster Management with technical support from the National Food Policy Capacity Strengthening Programme (NFPCSP) ISBN 978‐984‐33‐5416‐7 Published by FPMU, Ministry of Food and Disaster Management. For copies/update on the Monitoring Report please contact: DG, FPMU – Khadya Bhaban, 16 Abdul Ghani Road, Dhaka‐1000; dg@fpmu.gov.bd ii Table of contents ______...
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...the topic of research. The host tomato, and the effectiveness of casual pathogen with in conducive environment, resulting wilt disease. As a host Tomato provide a unique variety of nutrients. Such as lutein, and zeaxanthin); flavonoids (including naringenin, chalconaringenin, rutin, kaempferol, and quercetin); carotenoids (including beta-carotene, (including caffeic, ferulic, and coumaric acid); hydroxycinnamic acids, glycosides (including esculeoside A); and fatty acid derivatives (including 9-oxo-octadecadienoic acid). Nutritional Significance of Tomato: Tomatoes are an excellent source of vtamin C and vitamin A as well as vitamin K which makes repairs, bone-healthy and heart-healthy, potassium keeps healthy heart , vitamin B6, folate, and dietary fiber; these are very good source of enzyme-promoting molybdenum; manganese a blood sugar-balancing factor. In addition, tomatoes are a good source of niacin, heart-healthy magnesium and vitamin E; energy-producing iron, vitamin B1, and bone-healthy copper and phosphorus; muscle-building protein. The following chart shows the nutrients for which this food is either an excellent, very good, or good source. One cup raw Tomatoes of weighing 180 gm contain 32.40 calories. Nutrient | Amount | DV (%) | Nutrient...
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...Periodic Intensification of ROUTINE IMMUNIZATION PRE-PRINT RELEASE Lessons Learned and Implications for Action Cover photos courtesy: TopLeft: UNICEF TopRight: UNICEF/El Salvador/Gonzalo Bell BottomLeft: WHO BottomRight: AED/Berengere DeNegri Periodic Intensification of ROUTINE IMMUNIZATION Lessons Learned and Implications for Action e Department of Immunization, Vaccines and Biologicals thanks the donors whose unspecified financial support has made the production of this document possible. is document was produced by the IMMUNIZATIONbasics Project, funded by the U.S. Agency for International Development (Cooperative Agreement #GHS-A-00-04-00004-00) and the Expanded Programme on Immunization team of the Department of Immunization, Vaccines and Biologicals Ordering code: WHO/IVB/____ Printed: _____2009 is publication is available on the Internet at: www.who.int/vaccines-documents/ www.immunizationbasics.jsi.com Copies of this document as well as additional materials on immunization, vaccines and biologicals may be requested from: World Health Organization Department of Immunization, Vaccines and Biologicals CH-1211 Geneva 27, Switzerland • Fax: + 41 22 791 4227 • Email: vaccines@who.int • © World Health Organization 2009 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel: +41 22 791 3264; fax: +41 22 791...
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...Food, Nutrition and Poverty Among Asylum-Seekers in North-West Ireland Mary Manandhar, Michelle Share, Sharon Friel, Orla Walsh, Fiona Hardy Combat Poverty Agency Working Paper Series 06/01 ISBN: 1-90548-512-3 May 2006 FOOD, NUTRITION AND POVERTY AMONG ASYLUM-SEEKERS IN NORTH-WEST IRELAND A collaborative study by the Health Service Executive – North Western Area and the Centre for Health Promotion Studies, National University of Ireland, Galway. With funding from Combat Poverty Agency Report authors: M Manandhar, M Share, S Friel, O Walsh and F Hardy (2006) FOOD, NUTRITION AND POVERTY AMONG ASYLUM-SEEKERS IN NORTH-WEST IRELAND Research Team Members HSE Western Area National University of Ireland, Galway (formerly North Western Health Board) Dr Mary Manandhar Senior Research Officer Public Health Department Dr Sharon Friel Lecturer Centre for Health Promotion Studies Ms Michelle Share Senior Research Officer Public Health Department Ms Orla Walsh Researcher Centre for Health Promotion Studies Dr Fiona Hardy Regional Coordinator for Services for Asylum Seekers and Refugees Ms. Theresa Shyrane Community Health Adviser Community Services, County Donegal March 2006 Food, nutrition and poverty among asylum seekers in NW Ireland Manandhar et al. Contents Page List of Tables List of Figures Abstract Executive Summary Introduction 1 1 5 1.1 Rationale and aims of the research 6 ...
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...Report 2012 Inside 2 5 6 7 8 10 12 14 16 20 46 58 70 72 Message to Stakeholders Fast Facts The Nestlé Legacy Organisation Structure The Nestlé Creating Shared Value Strategy Engaging Our Stakeholders Governance Summary of Key Performance Data Our Respect and Care for the Community Our Commitment to the Environment Our People and the Workplace Our Consumers and the Marketplace Awards & Achievements GRI Standard Disclosures COVER: One of Nestlé Malaysia’s key successful rural development programmes has been its contract farming initiatives, where farmers are actively engaged to be part of the Nestlé supply chain. In February 2012, the Nestlé Paddy Club was introduced with the aim of increasing field productivity and lowering production costs, whilst reducing rice-farming’s environmental footprint, as well as enhancing overall farming safety aspects at the contract farms in Kedah. Nestlé (Malaysia) Berhad 110925-W 16 1 Our Respect and Care for the Community 46 Our People and the Workplace 20 Our Commitment to the Environment At Nestlé, we believe that in order to create long-term value for our shareholders, we have to create value for society, subscribing to the view that corporate success and social development go hand in hand. 58 Our Consumers and the Marketplace 2 Nestlé (Malaysia) Berhad 110925-W Message to Stakeholders Creating Shared Value (CSV) is at the core of our business. That is how our company started off, with our...
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...E&Y Nutraceuticals Critical supplement for building a healthy India Contents Foreword................................................................................................... 04 Introduction............................................................................................. 06 Executive summary................................................................................ 07 An insight into the nutraceuticals market of India Section I: Nutritional status of the population of india....................................10 Section II: Nutraceuticals market: global and India.........................................24 Section III: Way forward............................................................................... 48 Annexure.................................................................................................. 66 Acknowledgements................................................................................ 76 Glossary....................................................................................................77 About FICCI..............................................................................................80 Foreword Ajit Singh Chairman- FICCI Task Force on Nutraceuticals Chairman- ACG Worldwide (formerly Associated Capsules Group) President- Health Foods and Dietary Supplements Association (HADSA) Dear reader, Nutraceuticals as they are called in industry parlance cover a basket of products from...
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...Contents Chapter 1 Chapter 2 Chapter 3 Chapter 4 Chapter 5 Chapter 6 Chapter 7 Chapter 8 Chapter 9 Chapter 10 Chapter 11 Chapter 12 Chapter 13 Chapter 14 Chapter 15 Chapter 16 Chapter 17 Chapter 18 Chapter 19 Chapter 20 Chapter 21 Chapter 22 Chapter 23 Introduction to Biochemistry Water Amino Acids and the Primary Structures of Proteins Proteins: Three-Dimensional Structure and Function Properties of Enzymes Mechanisms of Enzymes Coenzymes and Vitamins Carbohydrates Lipids and Membranes Introduction to Metabolism Glycolysis Gluconeogenesis, The Pentose Phosphate Pathway, and Glycogen Metabolism The Citric Acid Cycle Electron Transport and Oxidative Phosphorylation Photosynthesis Lipid Metabolism Amino Acid Metabolism Nucleotide Metabolism Nucleic Acids DNA Replication, Repair, and Recombination Transcription and RNA Processing Protein Synthesis Recombinant DNA Technology 1 10 27 46 65 85 104 119 137 153 169 185 199 213 227 241 256 269 284 300 315 330 348 Chapter 1 Introduction to Biochemistry 1) Which elements account for more than 97% of the weight of most organisms? A) C, H, N, Mg, O, S B) C, H, N, O, P, S C) C, H, N D) Fe, C, H, O, P E) Ca2+ , K+ , Na+ , Mg 2+ , ClAnswer: B Page Ref: Section 2 2) Proteins in biological membranes may be A) porous. B) attached to the membrane surface. C) span the membrane. D) All of the above E) B and C only Answer: D Page Ref: Section 3 3) Which statement...
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