...The Science and Ethics of Genetic Engineering Research & Position Paper Table of Contents DNA Fingerprinting/ Genetically Modified Foods --------------------------------------------------- p. 3 Gene Therapy/Cloning------------------------------------------------------------------------------------ p. 4 Stem Cell Technology------------------------------------------------------------------------------------ p. 5 Position Paper------------------------------------------------------------------------------------------- p. 6-7 Bibliography-------------------------------------------------------------------------------------------- p. 8-10 Evaluation Rubric----------------------------------------------------------------------------------------- p. 7 DNA Fingerprinting DNA fingerprinting are tests that help to identify and analyze a person’s DNA. The term “fingerprinting” is used because finger prints, like DNA, vary from person to person and no two people have the same DNA or fingerprints. So, when scientists identify a person’s DNA, it can only be linked back to one individual and can help to obtain information about that specific individual. DNA fingerprinting can be done through many different ways. Some ways are through blood samples from a vein or heel, saliva samples, skin samples, or hair samples. The purpose of DNA fingerprinting is to help link family members together, find things that cause diseases, to help aid in crime scene investigations, and to...
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...develop or make useful products, or "any technological application that uses biological systems, living organisms or derivatives thereof, to make or modify products or processes for specific use" (UN Convention on Biological Diversity).[1] Depending on the tools and applications, it often overlaps with the (related) fields of bioengineering and biomedical engineering. For thousands of years, humankind has used biotechnology in agriculture, food production and medicine.[2] The term itself is largely believed to have been coined in 1919 by Hungarian engineer Karl Ereky. In the late 20th and early 21st century, biotechnology has expanded to include new and diverse sciences such as genomics, recombinant gene technologies, applied immunology, and development of pharmaceutical therapies and diagnostic tests.[3] Definitions of biotechnology The concept of 'biotech' or 'biotechnology' encompasses a wide range of procedures (and history) for modifying living organisms according to human purposes — going back to domestication of animals, cultivation of plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. Biotechnology is defined by the American Chemical Society as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials...
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...complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy Alba Luengo1, Lucas B Sullivan1 and Matthew G Vander Heiden1,2* Abstract Metformin has been a first-line treatment for type II diabetes mellitus for decades and is the most widely prescribed antidiabetic drug. Retrospective studies have found that metformin treatment is associated with both reduced cancer diagnoses and cancer-related deaths. Despite the prevalence of metformin use in the clinic, its molecular mechanism of action remains controversial. In a recent issue of Cancer & Metabolism, Andrzejewski et al. present evidence that metformin acts directly on mitochondria to inhibit complex I and limits the ability of cancer cells to cope with energetic stress. Here, we discuss evidence that supports the role of metformin as a cancer therapeutic. See research article: http://www.cancerandmetabolism.com/content/2/1/12. The biguanide metformin is an antihyperglycemic agent used to treat type II diabetes. Metformin decreases blood glucose levels by suppressing liver gluconeogenesis and stimulating glucose uptake in skeletal muscle and adipose tissues. Metformin is prescribed to over 120 million people, providing a wealth of epidemiological data. Retrospective studies have found that metformin treatment is associated with diminished tumorigenesis, with a recent meta-analysis of these studies reporting a 31% reduction in cancer incidence and a 34% reduction in...
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...(Layli Stroia) ……………………………………………………..… 30 Outline A brief description of the technology and an explanation of the associated science Definition: What is Genetic Engineering? Genetic engineering (GE) is the process of manipulation of an organism genome to create a new DNA. The new DNA might be implanted in a totally different DNA species. It is widely used to create hybrids (some species are not able to naturally breed), correct genetic flows in any type of being. It is applied in fields such as agriculture, industrial, medicine and pharmaceutical. (Aldridge, 1996). As Primrose explained, gene manipulation involves the creation and cloning of artificially created DNA (recombinant DNA) that provides with DNA sequences not found in nature. This created DNA is introduced in a host living cell. “…genetic engineering is a 'cut, paste, and copy' operation. The gene...
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...present one side of the argument or another. That is not the point. Many scholarly sources for example, are likely to provide you with arguments that you will use for both sides of your controversy. While you don’t have to worry about choosing the same number of “for” articles and “against” articles, it is important to make sure you have a balanced number of arguments for each side of your debate. Finally, you also don’t need to separate your popular and scholarly sources as they are likely to examine similar issues. You don’t want to be repetitive when describing various arguments, so think about a way of effectively organizing the arguments you will presenting. Your paper is essentially going to be divided in two parts. The first part will be about describing the arguments on either side of the debate. I call this the descriptive component of your paper. The second part of your paper is the analysis. You will be analyzing two things. First, I want you to compare and contrast how your topic is presented in scholarly versus popular media. Think of areas like language (simple versus complex), use of references, and length of article as a starting point for your analysis. Make sure to use examples in your analysis. For instance, if you tell me that scholarly sources are harder to understand than popular ones because of language, provide an example of this from your own sources. The other thing I want you to analyze is how your topic relates to any one or two of our course themes...
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...transplantation of hES cell‐derived equivalents would restore normal function. On the other hand, the use of hES cells is highly controversial because they are derived from human pre‐implantation embryos. To date, most embryos used for the establishment of hES cell lines have been spare embryos from IVF, but the creation of embryos specifically for deriving hES cells is also under discussion. The most controversial variant of this is the transfer of a somatic cell‐nucleus from a patient to an enucleated oocyte (unfertilized egg) in order to produce hES cells genetically identical to that patient for ‘autologous’ transplantation (so‐called ‘therapeutic’ cloning); this may prevent tissue rejection. The question ‘Can these cells be isolated and used and, if so, under what conditions and restrictions’ is presently high on the political and ethical agenda, with policies and legislation being formulated in many countries to regulate their derivation. The UK has been the first to pass a law governing the use of human embryos for stem cell research. The European Science Foundation has established a committee to make an inventory of the positions taken by governments of countries within Europe on this issue (European Science Foundation, 2001). In order to discuss the moral aspects of the isolation and use of hES cells, which is the aim of the present article, it is first...
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...LYMPHOID NEOPLASIA ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling Lilian Kuster,1 Reinhard Grausenburger,1 Gerhard Fuka,1 Ulrike Kaindl,1 Gerd Krapf,1 Andrea Inthal,1 Georg Mann,2 Maximilian Kauer,1 Johannes Rainer,3 Reinhard Kofler,3 Andrew Hall,4 Markus Metzler,5 Luder Hinrich Meyer,6 Claus Meyer,7 ¨ Jochen Harbott,8 Rolf Marschalek,7 Sabine Strehl,1 Oskar A. Haas,2 and Renate Panzer-Grumayer1,2 ¨ Cancer Research Institute, St Anna Kinderkrebsforschung, Vienna, Austria; 2St Anna Kinderspital, Vienna, Austria; 3Tyrolean Cancer Research Institute and Biocenter - Division Molecular Pathophysiology, Innsbruck Medical University, Innsbruck, Austria; 4Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom; 5Department of Pediatrics, University of Erlangen-Nuremberg, Erlangen, Germany; 6Department of Pediatrics and Adolescent Medicine, University of Ulm, Ulm, Germany; 7Institute of Pharmacological Biology/DCAL, Goethe-University, Frankfurt, Germany; and 8Onkogenetic Laboratory, Department of Pediatric Hematology/Oncology, Justus-Liebig-University, Gießen, Germany 1Children’s Approximately 25% of childhood acute lymphoblastic leukemias carry the ETV6/RUNX1 fusion gene. Despite their excellent initial treatment response, up to 20% of patients relapse. To gain insight into the relapse mechanisms, we analyzed single nucleotide polymorphism arrays for DNA...
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...Playing with life, Playing with rules? Have you or someone that you’ve known, maybe someone dear to you, ever lost a limb? Then you may have heard of stem cell research. Embryonic stem cells have the amazing ability to theoretically grow back any body part. They have the potential to morph into any of the 220 cell types found in the body (Robinson 1). It has the restoration power capable of reestablishing functions of the body as well, such as eyesight. The drawback to stem cell research is that it requires baby fetuses to acquire the material. Stem cells differ from other cells in the body, as they are capable of dividing and rebuilding themselves for long durations of time. This is unlike muscle cells, blood cells, or nerve cells. They are not able to replicate themselves, while stem cells can do it many times. This means that if stem cells are kept in a laboratory over a long period of time, they can yield many other stem cells. Another property of stem cells is that they are unspecialized, meaning that they do not help with anything in the body. For example, they are not able to help the heart pump blood in the body. However, stem cells can become heart muscle cells and blood cells, which could do that function. A third property of stem cells is that they become specialized cells. This is called differentiation, when the stem cell morphs into a cell that will have a specific function in the body (Robinson 1). In the last five years, China has increased its research funding...
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...THEORETICAL BACKGROUNDS FOR UNDERSTANDING HOMOSEXUALITY................................................................................................... 9 HOMOSEXUALITY FROM A BEHAVIOURISTIC POINT OF VIEW ................................ 10 HOMOSEXUALITY FROM A BIOLOGICAL POINT OF VIEW ....................................... 16 HOMOSEXUALITY FROM A PSYCHODYNAMIC POINT OF VIEW............................... 23 TREATMENT TODAY............................................................................................ 29 RELIGIOUS ORGANIZATIONS................................................................................... 30 SCIENTIFIC ORGANIZATIONS .................................................................................. 34 THERAPY METHODS...
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...Republic of the Philippines Laguna State Polytechnic University San Pablo City Campus College of Arts and Sciences Bachelor of Science in Psychology Submitted to: Ms. Evangeline Dia Understanding Aggression Handed on February 5, 2014 By: Camille L. Quicho Student no. 11-00131 Psychology (BS), 2nd semester CONTENTS 1 Introduction………………………………………………………………………1 2 What is Aggression………………………………………………………………2 3 Disorders linked from Aggression……………………………………….. ~1~ 1- INTRODUCTION Psychologists classify aggression as instrumental and hostile. Instrumental aggression is aggressive behavior intended to achieve a goal. It is not necessarily intended to hurt another person. For example, a soccer player who knocks a teammate down as they both run to stop the ball from reaching the opposing team's goalpost is not trying to hurt the teammate. Hostile aggression, onthe other hand, is aggressive behavior whose only purpose is to hurt someone.Hostile aggression includes physical or verbal assault and other antisocialbehaviors. Most studies of aggression are geared toward hostile aggression. There are several forms of self-control training, which teaches people to control their own anger and aggression by making verbal statements in which the person tells him/herself to respond to anger and arousal by thinking first and then using less aggressive behavior. Self-control training includes rational restructuring, cognitive self-instruction, and stress inoculation. Self-control...
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...is itself remarkable. We're so exquisitely privileged to be living in this time, to be born right on the precipice of the greatest paradigm shift in human history, the only thing that approaches the importance of that reality is finding like minds that realize the same, and being able to make some connection with them. If these books have influenced you the same way that they have us, we invite your contact at the email addresses listed below. Enjoy, Michael Beight, piman_314@yahoo.com Steven Reddell, cronyx@gmail.com Here are some new links that we’ve found interesting: KurzweilAI.net News articles, essays, and discussion on the latest topics in technology and accelerating intelligence. SingInst.org The Singularity Institute for Artificial Intelligence: think tank devoted to increasing Humanity’s odds of experiencing a safe, beneficial Singularity. Many interesting articles on such topics as Friendly AI, Existential Risks. A SingInst.org/Media Videos, audio, and PowerPoints from the Singularity Summits; and videos about SIAI’s purpose. blinkx.com/videos/kurzweil Videos on the internet in which the word “Kurzweil” is spoken. Great new resource! PRAISE FOR THE...
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...claire.robinson@earthopensource.org June 2012 Disclaimer The views and opinions expressed in this paper, or otherwise published by EOS, are those of the authors and do not represent the official policy, position, or views of other organizations, universities, companies, or corporations that the authors may be affiliated with. GMO Myths and Truths 2 About the authors Michael Antoniou, PhD is reader in molecular genetics and head, Gene Expression and Therapy Group, King’s Cols: lege London School of Medicine, London, UK. He has 28 years’ experience in the use of genetic engineering technology investigating gene organisation and control, with over 40 peer reviewed publications of original work, and holds inventor status on a number of gene expression biotechnology patents. Dr Antoniou has a large network of collaborators in industry and academia who are making use of his discoveries in gene control mechanisms for the production of research, diagnostic and therapeutic products and safe and efficacious human somatic gene therapy for inherited and acquired genetic disorders. Claire Robinson, MPhil, is research director at Earth Open Source. She has a background in investigative reporting and the communication of topics relating to public health, science and policy, and the environment. She is an editor at GMWatch (www.gmwatch.org), a public information service...
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...What is Cloning? Clones are organisms that are exact genetic copies. Every single bit of their DNA is identical. Clones can happen naturally—identical twins are just one of many examples. Or they can be made in the lab. Below, find out how natural identical twins are similar to and different from clones made through modern cloning technologies. How Is Cloning Done? Many people first heard of cloning when Dolly the Sheep showed up on the scene in 1997. Artificial cloning technologies have been around for much longer than Dolly, though. There are two ways to make an exact genetic copy of an organism in a lab: artificial embryo twinning and somatic cell nuclear transfer. 1. Artificial Embryo Twinning Artificial embryo twinning is a relatively low-tech way to make clones. As the name suggests, this technique mimics the natural process that creates identical twins. In nature, twins form very early in development when the embryo splits in two. Twinning happens in the first days after egg and sperm join, while the embryo is made of just a small number of unspecialized cells. Each half of the embryo continues dividing on its own, ultimately developing into separate, complete individuals. Since they developed from the same fertilized egg, the resulting individuals are genetically identical. Artificial embryo twinning uses the same approach, but it is carried out in a Petri dish instead of inside the mother. A very early embryo is separated into individual cells, which are allowed...
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...Lung cancer From Wikipedia, the free encyclopedia This article is about lung carcinomas. For other lung tumors, see Lung tumor. Lung cancer Classification and external resources LungCACXR.PNG A chest X-ray showing a tumor in the lung (marked by arrow) ICD-10 C33-C34 ICD-9 162 DiseasesDB 7616 MedlinePlus 007194 eMedicine med/1333 med/1336 emerg/335 radio/807 radio/405 radio/406 MeSH D002283 Lung cancer (also known as carcinoma of the lung) is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung. If left untreated, this growth can spread beyond the lung by process of metastasis into nearby tissue or other parts of the body. Most cancers that start in the lung, known as primary lung cancers, are carcinomas that derive from epithelial cells. The main primary types are small-cell lung cancer (SCLC), also called oat cell cancer, and non-small-cell lung cancer (NSCLC). The most common symptoms are coughing (including coughing up blood), weight loss, shortness of breath, and chest pains.[1] The most common cause is long-term exposure to tobacco smoke,[2] which causes 80–90% of lung cancers.[1] Nonsmokers account for 10–15% of lung cancer cases,[3] and these cases are often attributed to a combination of genetic factors,[4] and exposure to; radon gas,[4] asbestos,[5] and air pollution[4] including second-hand smoke.[6][7] Lung cancer may be seen on chest radiographs and computed tomography (CT) scans. The diagnosis is confirmed by biopsy[8]...
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...Biology guide First assessment 2016 Biology guide First assessment 2016 Diploma Programme Biology guide Published February 2014 Published on behalf of the International Baccalaureate Organization, a not-for-profit educational foundation of 15 Route des Morillons, 1218 Le Grand-Saconnex, Geneva, Switzerland by the International Baccalaureate Organization (UK) Ltd Peterson House, Malthouse Avenue, Cardiff Gate Cardiff, Wales CF23 8GL United Kingdom Website: www.ibo.org © International Baccalaureate Organization 2014 The International Baccalaureate Organization (known as the IB) offers four high-quality and challenging educational programmes for a worldwide community of schools, aiming to create a better, more peaceful world. This publication is one of a range of materials produced to support these programmes. The IB may use a variety of sources in its work and checks information to verify accuracy and authenticity, particularly when using community-based knowledge sources such as Wikipedia. The IB respects the principles of intellectual property and makes strenuous efforts to identify and obtain permission before publication from rights holders of all copyright material used. The IB is grateful for permissions received for material used in this publication and will be pleased to correct any errors or omissions at the earliest opportunity. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted...
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