DETERMINING EFFECTIVESS OF DELTAMETHRIN AND CARBOSULFAN, AND THEIR SYNERGIST EFFECT IN CONTROL OF MOSQUITOES

BY

OCHIENG’ JAMES WYCLIFFE S12/21157/12

A research proposal submitted to the Department of Biochemistry and Molecular Biology in partial fulfillment of the requirements for the award of Bachelor of Science in Biomedical Science & Technology of Egerton University.

EGERTON UNIVERSITY
2015

DECLARATION

I, Ochieng’ James Wycliffe, hereby declare that this proposal is my original work and has not been presented for award of a degree in any other university.

Candidate: Sign ……………………………… Date……………………………….. ….

RECOMMENDATION

Supervisors: This proposal has been submitted for examination with my approval as supervisor Dr. Vincent Adunga, Department of Biochemistry and molecular Biology, Egerton University.

Sign: …………………………………………Date: ……………………………………

ABSTRACT

The development and spread of insecticide resistance in the population of Anophene species, a major vector of malaria in Kenya, presents a serious threat to the progress made in malaria control interventions. This has significantly contributed to negative gains in eradication of mosquito population that spread malaria hence increased cases of deaths due to the disease. With this resistance to insecticides on the rise, surveillance of the target population for optimal choice of insecticides is a necessity. The objective of this study is thus to assess the level of insecticides resistance in malarial vectors population along river Njokerio in Egerton University region using the WHO susceptibility test. Three sentinel sites will be selected from the region and mosquitoes larvae sampled and reared to adults in the laboratory. Two to five days old mosquitoes will be assessed for resistance levels by exposing them to the discriminating doses of Deltamethrin (0.05%) and