...Mystica Dilallo Principles of Pharmacology Due: May 16, 2014 The Endocrine System The Endocrine system The endocrine system is a network of glands that produce and release hormones that help control many important body functions, especially the body's ability to change calories into energy that powers cells and organs. The endocrine system influences how your heart beats, how your bones and tissues grow, even your ability to make a baby. It plays a vital role in whether or not you develop diabetes, thyroid disease, growth disorders, sexual dysfunction, and a host of other hormone-related disorders. Each gland of the endocrine system releases specific hormones into your bloodstream. These hormones travel through your blood to other cells and help control or coordinate many body processes. Even the slightest hiccup with the function of one or more of these glands can throw off the delicate balance of hormones in your body and lead to an endocrine disorder, or disease. Adrenal insufficiency, the adrenal gland releases too little of the hormone cortisol and sometimes, aldosterone. Symptoms include fatigue, stomach upset, dehydration, and skin changes. Addison's disease is a type of adrenal insufficiency. All treatment for Addison's disease involves hormone replacement therapy to correct the levels of steroid hormones your body isn't producing. Some options for treatment include Oral corticosteroids, Corticosteroid injections, and Androgen replacement therapy...
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...The Endocrine System Dirty Sanchez BEH/225 Introduction to Behavioral Science 19 March 2014 Mrs. Piggy The Endocrine System Human behavior can be affected by several factors; a person’s upbringing, the surrounding environment, and one’s personality. These are all examples of what one sees on the outside of the body. Inside the body, there is a system that can have several effects on human behavior. This system is called the endocrine system. This system is made up of glands that secrete hormones into the lymph system, also known as the bloodstream. Glands such as the thyroid and adrenal secrete hormones that affect human behavior. The thyroid gland secretes thyroid hormones such as triiodothyronine (T3) and thyroxine (T4), which regulate the human body’s metabolism. The adrenal glands secrete hormones such as, adrenalin and noradrenalin which can be related to fear and anger. The endocrine system’s secretions of hormones throughout the human body plays a large role on how a human behavior. The Role of the Endocrine System Like the nervous system, the endocrine system goes hand-in-hand in controlling and coordinating the reflexes and reactions of the human body. The endocrine glands create and execute communications throughout the body that are just as important as the nervous system (Coon & Mitterer, p. 74, 2012). Through secretion of chemicals, also known as hormones, the endocrine system secretes these...
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...Endocrine System Functions: Help regulate: • Chemical composition and volume of internal environment • Metabolism and energy balance • Biological clock (circadian rhythm) • Contraction of smooth and cardiac muscle fibers Control growth and development Regulate operation of reproductive systems Nerve impulses Neurotransmitter Endocrine system Hormones Hormones : regulate physiological activities of target cells in the body Endocrine glands Secrete the products (hormones) into the interstitial fluid surrounding the secretory cells, rather than into ducts Exocrine glands Secrete their products into ducts ( ex. sudoriferous glands, sebaceous glands) Major Endocrine organs of the body Target cell: organs regulated/affected by the hormones Role of Hormone Receptors Down-regulation • When a hormone is present in excess, the number of target-cell receptors may decrease • Decreases the responsiveness of target cells to the hormone Up-regulation • When a hormone is deficient, the number of receptors may increase. Makes a target tissue more sensitive to a hormone. Classification: (How far from their site of production they act) Circulating hormones (endocrine) Pass into the blood and act on distant target cells Local hormones Act locally without first entering the blood stream Chemical classes of Hormones Lipid-soluble Hormones • Steroid hormones • Thyroid hormones (T3/T4) • Nitric oxide Water - soluble Hormones • Amine...
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...The Endocrine System BIO / 101 The Endocrine System The endocrine system is defined as any system within an animal that regulates the functioning of the organism or is used in the production of hormones. These systems can range anywhere from a simple center in the nervous system to a more intricate collection of glands that are in the human endocrine system. Qualified endocrinologists have been analyzing the advancement of the endocrine systems and the roles that they play in an animals’ adaptive behavior in an environment as well as their production of offspring. It is surprising to find that the research of endocrinology in mammals has been advanced by research in non-mammal animals. For example, the mechanisms in the body that control salt and water content were discovered in fishes first, this led to the discovery of comparable functions in mammals. The understanding in how the endocrine system is structured in non-mammals offers critical information into understanding how the human endocrine system functions. The most basic endocrine system deals with the secretion and storage of hormones within nervous tissue or neurohemal organs. These hormones can be secreted directly into circulation of the body or stored into organs that have direct contact with the blood vessels that allow the hormones to be put into circulation. There are cells located within the endocrine glands that stem from various nerve cells that have traveled during the evolutionary process to different...
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...make breast milk to feed a baby. Other glands release hormones (say: hor-mones), which are substances inside your body that tell it how to work and how to grow. Glands that do this are part of the endocrine (say: en-doh-krin) system. Puberty — body changes that turn a kid into an adult — depend on the endocrine system. Still other things that we call "glands" are part of your immune (say: ih-myoon) system. They release substances that help you fight off illnesses and, if you are sick, help you get better. When you have a bad cold and your neck glands are swollen, that is your immune system in action. Exocrine glands are a type of ductal glands that secrete their products (including digestive enzymes, and some hormone chemical messengers) into ducts that lead directly into the external environment. They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. The hypothalamus (from Greek ὑπό = under and θάλαμος = room, chamber) is a portion of the brain that contains a number of small nuclei with a variety of functions. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis). The hypothalamus is located under the thalamus, one of the most evolutionarily ancient parts of the human brain, which is located directly at its...
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...Endocrine disruptors Max Powers Describe endocrine disrupters. Endocrine disruptors are chemicals that can interfere with the hormonal system in humans, and other species of animals. (Endocrine Disruptors , 2016) Even at low levels of dosage, endocrine disruptors can cause cancerous tumors, birth defects, and other developmental disorders. Endocrine disruptors can severely harm to any system in the body controlled by hormones by interfering with the natural behavior of those hormones. Commonly, endocrine disruptors are associated with the development of learning disabilities, cognitive and brain development problems; deformity of the body (including limbs); certain cancers; and sexual development problems such as feminizing of males or masculinizing effects on females. Exposure to endocrine disruptors can be found in inhaling of household products, additives added to products such as plastics, and exposure to contaminated food treated with man-made chemicals. Because of endocrine disrupters, why did Congress amend the Food Quality Protection Act and the Safe Water Drinking Act in 1996? Congress amended the FQPA and safe water drinking act in 1996 to provide a directive for more testing to the chemicals that were being put in the water and food sources. Making information more transparent about the pesticides and substances used and providing a standard of using chemicals that caused little to no harm to the consumer. The amending of the directives especially addressed...
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...A variety of chemicals have been shown to disrupt female reproductive function throughout the lifespan in laboratory animals and humans (e.g., diethylstilbestrol). These effects include the disruption of normal sexual differentiation, ovarian function (i.e., follicular growth, ovulation, corpus luteum formation and maintenance), fertilization, implantation, and pregnancy. Only a few agents are associated with direct interference with the endocrine reproductive axis. Examples are those with estrogenic activity or the potential to interact with the aryl hydrocarbon (Ah) receptor. Exposure to toxicants during development is of particular concern because many feedback mechanisms functioning in the adult are absent and adverse effects may be noted at doses lower than those observed in the adult. Endometriosis is a painful reproductive and immunologic disease of women characterized by aberrant location of uterine endometrial cells. It affects approximately 5 million women in the United States from 15 to 45 years of age and often causes infertility. The etiology of this disease is unknown. In a single study with a small number of animals, research has suggested a link between dioxin exposure and the development of endometriosis in rhesus monkeys. The severity of this lesion was dependent on the dose administered. Recently, a small pilot study to test the hypothesis that serum dioxin concentrations have an association with human endometriosis has been reported. No statistically significant...
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...1) Endocrine System- the endocrine system is a collection of glands in an organism that releases hormones into the circulatory system which are carried toward the organs. The endocrine system has many parts it for example the pancreas. 2) Steroid Hormones-enhances the growth of organisms. An example of steroid hormones is aldosterone. Steroid Hormones is important to the article because it’s the main cause for the endocrine system disruption. 3) Androgen- a synthetic steroid hormone, an example is trenbolone, it is important to the article because is one of the hormones that reverts at night and it causes scientist to experiment with it. 4) Fecundity-ability to produce an abundance of offspring, an example is an organism that has lots of offspring, it describes the reduction of the fish and the skew....
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...Endocrine glands hypothalamus: The hypothalamus is a part of the brain located superior and anterior to the brain stem and inferior to the thalamus. It helps many different functions in the nervous system, and is also responsible for the direct control of the endocrine system through the pituitary gland. The hypothalamus contains special cells called neurosecretory cells—neurons that secrete Pituitary gland: The pituitary gland, also known as the hypophysis, is a small pea-sized lump of tissue connected to the inferior portion of the hypothalamus of the brain. Many blood vessels surround the pituitary gland to carry the hormones it releases throughout the body. Situated in a small depression in the sphenoid bone called the sella turcica, the pituitary gland is actually made of 2 completely separate structures: the posterior and anterior pituitary Anterior Pituitary: the true glandular part of the pituitary gland. The function of the anterior pituitary gland is controlled by the releasing and inhibiting hormones of the hypothalamus. The anterior pituitary produces 6 important hormones: Thyroid gland: The thyroid gland is a butterfly-shaped gland located at the base of the neck and wrapped around the lateral sides of the trachea. The thyroid gland produces 3 major hormones: Parathyroid gland: are 4 small masses of glandular tissue found on the posterior side of the thyroid gland. The parathyroid glands produce the hormone parathyroid hormone (PTH), which...
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...Endocrine System Hormones Directions: Fill in the following table. |Hormone |Endocrine Gland/Source |Controls/Responsible for What? | |Estrogen |ovaries |Responsible for the growth and development of female sexual | | | |characteristics and reproduction. | |Oxytocin |Hypothalamus |Stimulates contraction of the myometrium in the uterus and contractions | | | |of the myoepithelial cells of the mammary glands. | |Leptin |Adipose tissue |Regulates appetite and energy expenditure. | |LH |Anterior Pituitary Gland |Triggers ovulation in females, stimulates leydig cell production of | | | |testosterone in males. | |Testosterone |Testicles |Responsible for the growth and development of male sexual characteristics| | | |and the production of body hair. | |Dopamine |Sustania nigra |A neurotransmitter that brings...
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...elsewhere in the body, or in a body cavity. TWO KINDS OF GLANDS EXOCRINE GLANDS The secretion of the exocrine glands pass through a duct to the site where they take effect. Examples Salivary glands - Saliva Sweat glands - Perspiration Mammary glands - Milk ENDOCRINE GLANDS The gland known as ductless or endocrine glands secrete their product directly into the bloodstream. The term ductless indicates that no duct cones out from the glands. Their secretion are called hormones, also known as chemical messengers. They regulate and integrate body functions. ENDOCRINE SYSTEM The endocrine system refers to the collection of glands of an organism that secrete hormones directly into the circulatory system to be carried towards distant target organs. It is a system that controls body functions such as sleep, sexual behavior, digestion, metabolism, and physical development. The endocrine system is an information signal system like the nervous system, yet its effects and mechanism are classifiably different. The endocrine system's effects are slow to initiate, and prolonged in their response, lasting from a few hours up to weeks. In vertebrates, the hypothalamus is the neural control center for all endocrine systems. The communication begins at the base of the forebrain with the hypothalamus. The hypothalamus sends messages to the pituitary gland, which then secretes hormones into the bloodstream, affecting glands throughout the body. HYPOTHALAMUS The hypothalamus synthesizes...
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...Debate The endocrine system is comprised of organs, tissues, and cells that secrete hormones vital to homeostasis. There are two major coordination communication types of body function endocrine and neural. The endocrine coordination communication type involves the chemical signaling and releases hormones into the extracellular fluid. While the neural coordination communication involves both the chemical as well as the electrical signaling between neurons and target cells. Endocrine communication is comprised of chemical signaling being release as the hormones are into the extracellular fluid. From that point hormones are diffused into the blood and may travel to distant body parts where they provoke a response in the target cells. Further, the endocrine glands have no duct as they secrete hormones. Many organs have primary functions to secret hormones such as the heart, kidneys, and stomach (OpenStax, 2013). This is how the endocrine glands works in conjunction with other systems to maintain homeostasis....
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...purpose of the circulatory system is to transport substances from place to place in the body. Blood is the liquid medium in which these materials travel, blood vessels ensure the proper routing of blood to its destinations, and the heart is the pump that keeps the blood flowing. More specifically, the functions of the circulatory system are as follows: Transport * The blood carries oxygen from the lungs to all of the body's tissues, while it picks up carbon dioxide from those tissues and carries it to the lungs to be removed from the body. * It picks up nutrients from the digestive tract and delivers them to all of the body's tissues. * It carries metabolic wastes to the kidneys for removal. * It carries hormones from endocrine cells to their target organs. * It transports a variety of stem cells from the bone marrow and other origins to the tissues where they lodge and mature. Protection * The blood plays several roles in inflammation, a mechanism for limiting the spread of infection. * White blood cells destroy microorganisms and cancer cells. * Antibodies and other blood proteins neutralize toxins and help to destroy pathogens. * Platelets secrete factors that initiate blood clotting and other processes for minimizing blood loss. Regulation * By absorbing or giving off fluid under different conditions, the blood capillaries help to stabilize fluid distribution in the body. * By buffering acids and bases, blood proteins help to...
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...Breonna Mosely 7/17/2014 Dr. Ganser Endocrine system effects on Sleep Deprivation Deprived sleep is a universal widespread problem observed in both children and adults. It is a vital process that helps in the functioning of learning, memory processing, cellular repair, and brain development. Statistics show that the average total hours of sleep have decreased per person to less than 7 hours per night over the past 3 to 4 decades. Many people experience sleep loss due pressures at work, stress, and our day to day lifestyle. The reduced hours of nocturnal sleep have shown to lead to serious health problems such as depression, obesity, hypertension, along with many other diseases. It also affects cognitive performance and emotionality. (1) The Endocrine system is responsible for the body’s stress systems and the release of the stress hormones necessary for adaptation and survival in the environment. Sleep deprivation are associated with increases in the hypothalamic- pituitary-adrenal axis, increased levels of cortisol and autonomic sympathetic activation and increased catecholamine levels during wakefulness. Increased sympathetic levels causes an increase in heart rate and blood pressure. Just briefly waking up from sleep for only a few seconds is associated with autonomic reflex, causing a temporary rise in heart rate and BP to the level seen while awake. This is more related to disruption and discontinuity of sleep than to the duration of sleep deprivation or...
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...The Endocrine System: Diseases and Age Related Changes Unit 10 assignment The Endocrine System: Diseases and Age Related Changes Unit 10 assignment CUSHING’S DISEASE: Cushing’s disease is when the pituitary gland releases too much adrenocorticotropic. The pituitary gland is a part of the endocrine system. This is disease is caused by a tumor or hyperplasia of the pituitary gland. The most common cause of this disease is known as adenoma, a benign tumor. With this disease the pituitary gland begins to overproduce ACTH which then causes the body to respond by over producing cortisol. Too much cortisol in the system can interfere with the bodies way of handling inflammation. ADDISON’S DISEASE: Addison’s disease is a chronic endocrine system disease where the adrenal glands don’t produce enough cortisol or aldosterone. Cortisol is the body’s way of handling stress; it also helps break down all of your macronutrients. Aldosterone helps the kidneys regulate the amount of salt and water in the body. There are two types of Addison’s disease; primary adrenal insufficiency which is when the initial problem is with the adrenal glands themselves. The other form is known as secondary adrenal insufficiency which when the adrenal glands are affected by an outside problem. ACROMEGALY: Acromegaly is a hormonal disorder caused when pituitary gland produces too much of a growth hormone during adulthood. Acromegaly is not a common disorder and is not usually noticed for...
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