Factor V Leiden is a blood clotting disorder that is caused by inheriting the mutation of the Factor V protein gene from one parent or both parents. There are two copies of Factor V gene passed down by the parent, one is from the mother and one is from the father. Factor V Leiden allows blood clots to form more easily and can cause a condition called thrombophilia. Blood clots form deep in the legs and in the lungs, and they can be very dangerous. Factor V is one of the many blood proteins that are in your blood. Factor V is a blood protein that is needed to make blood clot. Factor V is controlled by another pontein called Active Protein C which helps control blood so it does not clot but, Factor V can override Active Protein C easily and because of this sometimes Factor V Leiden is referred to as Activated Protein C resistant. There are two types of Factor V Leiden, Heterozygous which is when you only inherit one Factor V gene form either the mother or the father. Then the body has only 50% Factor V Leiden and 50% normal Factor V. Out of 100people this happens to 5 people. The other type if Factor V Leiden is Homozygous which is when you inherited one gene from the mother and one from the father. The body has 100% of Factor V protein. …show more content…
Heterozygous Factor V Leiden slightly increases the chance of a blood clot developing and homozygous Factor V Leiden makes the chances of developing a blood clot significantly higher. Small children have a risk of 1 in 100,000 per year for developing a blood clot. People in their twenties have a risk of 1 in 10,000 per year for developing a blood clot. People in their forties have 1 in 1,000 per year for developing a blood clot and people in their eighties and older have the risk of 1 in 100 per year for developing a blood