...Chem‐106 Grignard Synthesis of Triphenylmethanol Objective: The purpose of this experiment is to synthesize triphenylmethanol from benzophenone via Grignard reaction. The product will be isolated through extractions and purified by recrystallization. Reaction efficiency will be evaluated through percent yield, percent recovery, and the purity of the final product will be determined by IR, TLC, and mp determination. Chemicals: bromobenzene, magnesium turnings, diethyl ether, benzophenone, biphenyl, triphenylmethanol, iodine, 6 M HCl, brine, anhydrous MgSO4 or Na2SO4, 10:90 EtOAc/hexanes. Glassware and equipment: 100 mL RBF, air condenser, Claisen adaptor, 60 and 125 mL addition funnel, short stem glass funnel, two 50 mL Erlenmeyer flasks, 10 mL graduated cylinder, lab jack, crystallizing dish, magnetic stir bar. Techniques: reflux, extraction, vacuum filtration, recrystallization, TLC, mp, IR spectroscopy. Introduction In 1912 Victor Grignard received the Nobel prize in chemistry for his work on the reaction that bears his name, a carbon-carbon bond-forming reaction by which almost any alcohol may be formed from appropriate alkyl halides and carbonyl compounds. The Grignard reagent RMgBr is easily formed by redox reaction of an alkyl halide with magnesium metal in anhydrous diethyl ether solvent. R-Br + Mg → RMgBr The Grignard reagent can be viewed as an ionic species consisting of carbanion R-, with Mg2+ counterion and an additional Br- counterion. The carbanion...
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...CH 220C ORGANIC CHEMISTRY LABORATORY Spring, 2015 Section Page 1. General Information 2 2. Safety Information 2 3. Attendance 3 Make-Up Policy 3 4. Laboratory Protocol 3 Assigned Reading 3 Pre-Lab Quizzes 3 Lab Notebook 5 Chemicals 5 Due Dates for Reports 5 5. Orientation 5 In-Lab Information 5 Library Information 5 6. Check-In 6 7. Grading Procedure 6 8. Policy on Cheating 7 9. TA Office Hours 8 10. Faculty Course CoordinatorS 8 11. Course Web Page 8 12. Hints to Minimize Frustration IN ORGANIC CHEMISTRY 8 13. Work Schedule 10 Lab Report Due Date Schedule 10 Experiments 10 14. Supplements 17 A. Extraction of Unknown 17 B. Recrystallization of Unknown Products 18 C. Methyl Benzoate 19 D. Synthesis of Luminol 20 E. Azo Violet 23 1. GENERAL INFORMATION PRE- and CO-REQUISITES Pre- and co-requisites for CH 220C listed in the Course Schedule. Important: Because the lecture and laboratory courses are co-requisites of each other, dropping one of them requires that you drop the other as well, unless the drop occurs during ...
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...Pentachlorophenol (PCP) in wood treatment 1.Introduction Wood is a hard, fibrous structural tissue found in the stems and roots of trees and other woody plants. It has been used for thousands of years for both fuel and as a construction material. It is an organic material, a natural composite of cellulose fibers (which are strong in tension) embedded in a matrix of lignin which resists compression. Wood is sometimes defined as only the secondary xylem in the stems of trees or it is defined more broadly to include the same type of tissue elsewhere such as in the roots of trees or shrubs. In a living tree it performs a support function, enabling woody plants to grow large or to stand up by themselves. It also mediates the transfer of water and nutrients to the leaves and other growing tissues. Wood may also refer to other plant materials with comparable properties, and to material engineered from wood, or wood chips or fiber. The Earth contains about one trillion tonnes of wood, which grows at a rate of 10 billion tonnes per year. As an abundant, carbon-neutral renewable resource, woody materials have been of intense interest as a source of renewable energy. In 1991, approximately 3.5 billion cubic meters of wood were harvested. Dominant uses were for furniture and building construction. The wood-preserving industry treats lumber with various chemicals to protect against insect damage and decay. Chemically preserved wood is used in products for outdoor use such as railway ties...
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