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Hemophilia

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There are two types of Hemophilia, A and B. Both are caused by deficiencies in the amount of clotting factor in the blood (VIII or IX). When the blood does not have enough of one of these or is missing one clotting factor, the bleeding may end very slowly or may not stop at all. The two types of Hemophilia are linked together by their similar clinical pictures and their similar inheritance patterns.
The most dangerous part about having Hemophilia is internal bleeding. If internal bleeding is left untreated it can lead to deformity, disability or even death. In a Hemophiliac the bleeding continues until either it clots long enough for it to heal or the person will bleed to death.
When a baby starts to crawl the parents may notice bruises on stomach, chest, buttock, and back.
The baby may also be difficult, not wanting to walk or crawl
Other symptoms include long nosebleeds, excessive bleeding from any kind of cut bruise or surgery.
The disease occurs at birth and is usually tested for.
17000 people are affected by the disease in the United States and 400,000 are affected across the globe
The disease is primarily in males
Hemophilia is a genetic disease and is passed on by the X chromosome (the chromosome that carries the clotting factor).
Hemophilia effects the F8 gene which is known as the blood clotting gene
The most common mutation in people with severe hemophilia A is a rearrangement of genetic material called an inversion. This inversion involves a large segment of the F8 gene.
Normally when a person is injured and is bruised or bleeding the blood clots and eventually stops the bleeding either internal or externally
But when a hemophiliac is injured or cut the blood does not flow faster out of their body it just takes a lot longer to stop because not enough of the blood clotting protein is produced to help stop the bleeding, so a person with

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