Historical Perspectives of the Diagnosis of Asthma in Children
1. Introduction:
The causes of Asthma:
Looking at some recent reports of asthma disease, most of the acute exacerbation because cold and phlegm caused by dysfunction of the lungs which occurred in sputum of asthma. Chronic repeatedly patients mostly offset organs function. Its complex etiology occurs due to some reasons of genetic, physical fitness, diet, environment, age, and other factors related to work and rest, and emphasize internal and external consistency due to infestation. Asthma patients in the onset of the disease is often accompanied by an abnormal increase in serum IgE, IgE is the primary antibody of Ι type hypersensitivity, when its binding to the antigen, mast cells and basophils release of large amounts of biologically active substances, causing a series Asthma disease symptoms, but also by the synthesis of IgE Ts cell regulation (Huang Zhiying 2011).
The physiological basis of Asthma:
There are many different causes of bronchial obstruction, which is the synonymous of asthma, such as bronchospasm, abnormalities, new growths, swelling of the bronchial mucosa and so on. Some causes may result in mechanical obstruction by new growth, foreign bodies and congenital abnormalities. There are also some secondary obstructions such as mucous secretions, bronchial mucosa swelling and bronchospasm. The reaction of bronchi to irritation with a kind of inside defense mechanism by human body. To antagonize the entrance of toxic reagents, or to shake off them. The reaction which is in the respiratory tract means what laryngospasm stand for some point in the higher respiratory tract which is named a kind of protective mechanism. The characters in the lower respiratory tract are named as bronchospasm which are the representation of coughing and mucous. The protective mechanism can be started up by an