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Initial Access Point for Coronary Angiography

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Coronary angiography refers to the radiographic visualization of the coronary vessels after injection of radiopaque contrast media. It is used to visualize the anatomy of the coronary arteries and deduce the extent of blockage of lumen. [1] The use of percutaneous coronary intervention is, but not restricted to, to treat coronary artery diseases. [2]
The American Heart Association uses Classes I, II, III to incorporate the indications and contraindications for the procedure. Class I incorporates conditions that prove the procedure is needed. Class II refers to findings challenge the efficiency of the procedure. Class III refers to all conditions which prove this procedure is not effective or harmful in some cases. [2]
The American Board of Surgery describes Class I conditions (clinical indications for angiography) as acute ST-Elevation Myocardial Infarctions (STEMI), Non ST-Elevation Acute Coronary Syndrome (NSTE-ACS), stable angina, variant and unstable angina. Immediate coronary angiography is recommended upon finding a patient with STEMI. For patients with NSTE-ACS, effective preventive and management is recommended. [3] For Class II patients, objective evidence of a moderate to large area of viable myocardium or moderate ischemia on non-invasive testing is an indication for angiography. Class III comprise of all clinical contraindications. These include intolerance to long term antiplatelet therapy, old age, presence of any comorbid conditions that limit the lifespan of patient. Arteries with diameters lesser than 1.5mm pose a threat and can lead to various risks. [3]
The possibility of key complications is less than 2%, but dynamics such as patient’s health, acute renal inefficiency, and cardiomyopathy elevate risk. The mortality rate is 0.45% (femoral 0.78%, radial 0.13%). [2] The incidence of myocardial infarction and cerebral embolism is high. The incidence rate is higher in femoral approach than radial approach. However, the incidence of arterial thrombosis and contrast agent reactions is higher in radial approach. Other complications include heparin induced Thrombocytopenia (immune-mediated complication), nephropathy, local vascular injury, hematoma and retroperitoneal haemorrhage, pseudo-aneurysm, and numerous cerebrovascular complications. [4]
The trans-femoral route for coronary angiography is the most common route for the procedure. However, trans-radial approach has gained progressive acceptance over last two decades largely due to low vascular complications. The radial artery is not directly associated with nearby nerves and veins allowing larger degree of compressibility. Since the hand receives dual blood supply, radial artery occlusions are perfused by extensive collateral flow. [5]
Trails have proved that the radial access reduces visualization of the site in comparison to a femoral approach. The radiation exposure and procedural times for trans-radial approach is higher than its counter-approach. Nevertheless, trans-radial access reduces major bleeding by 73% compared to trans-femoral access. The complications of death, myocardial infarction and stroke are reduced by 3.8%. [1]
For either approach, the potential benefits should be weighed against the established risk factors, morbidity and mortality. [5] After analysing and considering the pros and cons of each approach, I believe trans-radial intervention should be favoured over trans-femoral approach as an initial access point for coronary angiogram.
[494 Words]
REFERENCES
[1] Branislav G. B, Amir F Z P. "What Should We Know About Prevented, Diagnostic, and Interventional Therapy in Coronary Artery Disease"; Chapter 15: “Trans-radial Versus Trans-femoral Coronary Angiography”. Available at http://www.intechopen.com/books/what-should-we-know-about-prevented-diagnostic-and-interventional-therapy-in-coronary-artery-disease/transradial-versus-transfemoral-coronary-angiography#SEC7

[2] P J Scanlon, MD, A M Audet, MD, G J Dehmer, MD, et al. ACC/AHA Guidelines for Coronary Angiography: Executive Summary and Recommendations. American Heart Association Journal.2005; Available at http://circ.ahajournals.org/content/99/17/2345.long
[3] G A Stouffer III, MD. Percutaneous Coronary Intervention Technique 5th edition. United States of America. Medscape; 2014

[4] D F Adams, D B Fraser, H L Abrams; ‘The Complications of Coronary Arteriography’ in American Heart Association Journal.2008. Available at http://circ.ahajournals.org/content/48/3/609.short
[5] M Tavakol, S Ashraf, S J Brener. “Risks and Complications of Coronary Angiography: A Comprehensive Review” in Global Journal of Health Science.2012;4

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