...While Ash1 binds to the targeted DNA elements called Thrithorax-response elements (TREs) which is located in the Ultrabithorax. How this works, non-coding RNA is produced and retained at the TRE of UBX, helping activate the expression of the UBX gene, by doing so this function attacks the Ash1 to the TREs. This stage changes the function of the cells. Knowing this, they can now use the non-coding RNA to actively control the destiny. Over several years studies were conducted on how noncoding RNAs silences genes. The works that Dr Sauer and others have now gained a wider knowledge then what was previously thought to be. They had suggested understood how the genes could be silence, now they know exactly how they can be activated, this is a key factor to animal development. Taking into consideration for the research done on the “silencer gene” which must have been monumental for the first time that the scientist found out, getting a better understanding on how they could activate the gene was more than ecstatic to the research instead. I think that this article help get a...
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...Assignment topic: Liver Regeneration Submitted To : Dr.Samina By: Razia Saleem Quaid - e - Azam University Dept : Animal Sciences MSc 2nd Semester Index Page # 1. Introduction 3 2. Structure and functions of liver 3,4 3. Liver Regeneration 5 4. Two layers of defense against liver injury 5 5. Dynamics of liver regeneration 6 6. Stimuli of hepatic regeneration 7 7. Regeneration by hepatocytes (1st line of defense) 8 8. Signaling...
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...Of all gynecologic malignancies, ovarian cancer continues to have the highest mortality and is the most difficult to diagnose. In the United States female population, ovarian cancer ranks fifth in absolute mortality among cancer related deaths (13,000/yr). In most reported cases, ovarian cancer, when first diagnosed is in stages III or IV in about 60 to 70% of patients which further complicates treatment of the disease (Barber, 3). Early detection in ovarian cancer is hampered by the lack of appropriate tumor markers and clinically, most patients fail to develop significant symptoms until they reach advanced stage disease. The characteristics of ovarian cancer have been studied in primary tumors and in established ovarian tumor cell lines which provide a reproducible source of tumor material. Among the major clinical problems of ovarian cancer, malignant progression, rapid emergence of drug resistance, and associated cross-resistance remain unresolved. Ovarian cancer has a high frequency of metastasis yet generally remains localized within the peritoneal cavity. Tumor development has been associated with aberrant, dysfunctional expression and/or mutation of various genes. This can include oncogene overexpression, amplification or mutation, aberrant tumor suppressor expression or mutation. Also, subversion of host antitumor immune responses may play a role in the pathogenesis of cancer (Sharp, 77). Ovarian clear cell adenocarcinoma...
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...McGraw-Hill Create™ Review Copy for Instructor Espinoza. Not for distribution. Course BBE 4505 Omar Espinoza University Of Minnesota NATURAL RESOURCES McGraw-Hill Create™ Review Copy for Instructor Espinoza. Not for distribution. http://create.mcgraw-hill.com Copyright 2012 by The McGraw-Hill Companies, Inc. All rights reserved. Printed in the United States of America. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without prior written permission of the publisher. This McGraw-Hill Create text may include materials submitted to McGraw-Hill for publication by the instructor of this course. The instructor is solely responsible for the editorial content of such materials. Instructors retain copyright of these additional materials. ISBN-10: 1121789048 ISBN-13: 9781121789043 McGraw-Hill Create™ Review Copy for Instructor Espinoza. Not for distribution. Contents 1. Preface 1 2. Methods, Standards, and Work Design: Introduction 7 Problem-Solving Tools 27 3. Tex 29 4. Operation Analysis 79 5. Manual Work Design 133 6. Workplace, Equipment, and Tool Design 185 7. Work Environment Design 239 8. Design of Cognitive Work 281 9. Workplace and Systems Safety 327 10. Proposed Method Implementation 379 11. Time Study 413 12. Performance Rating and Allowances 447 13. Standard Data and Formulas 485 14. Predetermined Time Systems 507...
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