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Mycobacterium Tuberculosis

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Mycobacterium tuberculosis

Cintia Jimenez-Mendoza
Microbiology Summer I 2012

Taxonomy

Scientific classification | Kingdom: | Bacteria | Phylum: | Actinobacteria | Class: | Actinobacteria | Order: | Actinomycetales | Suborder: | Corynebacterineae | Family: | Mycobacteriaceae | Genus: | Mycobacterium | Species: | M. tuberculosis | Binomial name | Mycobacterium tuberculosis |
M. tuberculosis was discovered by Robert Koch in March 24 1882, who was a German physician and scientist. This specie is a pathogenic organism from the kingdom bacteria and genus Mycobacterium. This bacterium has caused most cases of tuberculosis which is an infectious disease caused by various strains of mycobacteria.
Koch said once that the importance of this organism was huge due to the fact that M. tuberculosis is lethal to humans; he said
"If the importance of a disease for mankind is measured by the number of fatalities it causes, then tuberculosis must be considered much more important than those most feared infectious diseases, plague, cholera..” [1]
Fig.1.Taxonomy of Mycobacterium tuberculosis [2]

The genus Mycobacterium includes pathogens that cause serious diseases like mentioned before tuberculosis and leprosy (Mycobacterium leprae). M. tuberculosis was also known as ‘tubercle bacillus’ or ‘Koch's bacillus’.
.
The Mycobacterium tuberculosis complex of organisms consists of other species like, Mycobacterium africanum which is mostly found in the West African countries, Mycobacterium bovis which cause tuberculosis in cattle, Mycobacterium microti, and Mycobacterium avium which causes disease especially prevalent in AIDS patients. The first three are now considered to be sub-species of M. tuberculosis.
“Mycobacterium tuberculosis was the cause of the "White Plague" of the 17th and 18th centuries in Europe. During this period nearly 100% of the

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