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Nt1310 Unit 1 Exercise 1

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The implications of the above results are discussed next.

As it can be seen in Figure 1, ESSENDON1 drug seemed to not to be effective in the Forced Swim Test experiment. The data shows that there is a higher percentage of immobility in the control group (mean = 54.3 +12.4%) compared to the ESSENDON1 test group (mean = 47.5 +7.6 %). This indicates that the test group demonstrated to have less escape - related behaviour and was found to be more anxious than the control group. Moreover, the t–test (p=0.6497) indicates there is ~65% chance that the immobility is the same and hence there is no significant differences between the two groups.

The bar graph of the Elevated plus-maze test in Figure 2 demonstrates the effectiveness of ESSENDON1. Through immediate observation, the …show more content…
While the forced swim test didn’t, one can argue that the experimental conditions were harsh, underlying a high potential for antidepressant assumption. Therefore, further FST tests need to be conducted to verify this assumption. Lastly, the NOR test provided that the drug was obviously not effective for enhancing memory. In the final analysis, the results are mixed, indicating categorially that the ESSENDON 1 was effective in reducing anxiety, but not for enhancing memory.
As ESSENDON 1 is unknown, one can only estimate what the pharmacology of the drug is. This study found the drug to be effective in reducing anxiety, and having anxiolytic effects. Further research is suggested to determine the serotonin levels, as anxiolytic drugs usually inhibit the reuptake of noradrenaline (NA) and serotonin into the presynaptic terminal adrenergic nerve. The Gamma-aminobutyric acid (GABA) levels also need to be investigated, as increasing in GABA neurotransmission mediates anxiolytic effects (Bystritsky. A., et al,

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