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Nt1310 Unit 3 Lab 3

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The purpose of this lab was to investigate an inherited disease by conducting a series of experiments. We conducted a total of four experiments. By looking at DNA for mutations, counting cells in mitosis to determine the rate of cell division, using pedigrees to hypothesize patterns of inheritance and using a larger worldwide data set from multiple families with the disease to test the predicted pattern of inheritance all contributes to the purpose of the lab, which mentioned before was to investigate and analyze an inheritable disease.
In Lab 3.1 we attempted to identify mutations in a gene associated with a newly discovered disease. Mutations are heritable changes in a gene’s nucleotide sequence. Mutations may change an individual’s phenotype or may have no affect at all. The central dogma of biology played a role in this part of the experiment. The central dogma of biology describes the flow of information in a cell.
In Lab 3.2 we analyzed data to see how a mutation in a gene affects the rate of cell division. Mitosis and Meiosis are two forms of cell division in eukaryotic cells. Here in Lab 3.2 we focused on Mitosis. Mitosis is when one cell, the parent cell, divides to …show more content…
Pedigrees can be used to help determine a pattern of inheritance in unknown or known diseases. If a trait follows Mendelian inheritance it may be passed on to offspring. There are many different types of inheritance such as autosomal dominant, autosomal recessive, or X-linked. It is important to know that if a trait skips a generation it is recessive, but a recessive trait doesn’t always skip a generation. A dominant trait won’t skip generations, but there can always be exceptions. By random chance parents with a disease can have normal children. X-linked traits are usually expressed more in males than females because men only have one X

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