...Middle-East Journal of Scientific Research 6 (5): 532-536, 2010 ISSN 1990-9233 © IDOSI Publications, 2010 Phytochemical Studies and in vitro Cytotoxicity Screening of Piper betle Leaf (PBL) Extract 1 Sundeep Chaurasia, 2G.T. Kulkarni and 1L.N. Shetty 1 Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, NH-58 Bypass Road, Baghpat Crossing, MEERUT 250 005 UP, India 2 Department of Pharmaceutics, Laureate Institute of Pharmacy, KATHOG 177 101 The. Dehra, Dist. Kangra, HP, India Abstract: Piper betle leaves (Family: Piperaceae) have been used in Chinese and Indian folk medicine for centuries and recently been proposed to be used as a chemopreventive agent because of its anti-oxidant activity. In the present paper, Piper betle leaves were standardized for stomatal index, vein islet and vein termination numbers, palisade ratio, UV fluorescence and different ash values. The Piper betle leaves are earlier reported to possess anticancer potential. Hence, the aqueous extract of the leaves was subjected to cytotoxicity studies on Hep-2 cell line using MTT and SRB assays. The mean CTC50 was found to be 96.25 µg/mL, which proved the potent cytotoxicity and hence, the probable anticancer property of the selected extract. Key words: Betel Leaf Anticancer Phytochemical characterization and its leaves, with a strong pungent and aromatic flavour, are widely consumed as a mouth freshener [4]. The leaves are credited with wound healing, digestive...
Words: 2882 - Pages: 12
...Case Study Analysis DLA Piper: Becoming a Global Firm Abstract The global business law firm DLA Piper did not arrive at its position as the recognized leader in its industry without a strategic plan to integrate and align it various regional entities. In fact, it was the vision of integration and alignment by its executive team that led to making DLA Piper the pre-eminent global business law firm today. This case study analysis will describe the setting & environment leading up to, during, and post-merger, then identify the stakeholders involved, and analyze the case context. In addition, Adler & Gundersen (2008) applications, along with options, decision factors and recommendations will be addressed. Setting and Environment In early 2005, two leading firms, DLA and Piper Rudnick, merged in the largest ever in the legal market. DLA, based in the UK, and Piper Rudnick, based in the USA, came together in order to establish a global platform and a foundation for accelerating growth. The two firms, along with US West Coast firm Cray Cary Ware and Freidenrich, became the merged DLA Piper. Initially, the firm would be led by three joint CEO’s who would have to address the issues that would make it a leading business global law firm. In order to achieve its strategic goal, the leadership of the new firm recognized that it must become aligned across its strategy, people, systems, structure, culture, and management. To achieve its express goal of becoming...
Words: 2625 - Pages: 11
...heaven. When she gets there she knows, if the stores are all closed With a word she can get what she came for. Ooh, ooh, and she's buying a stairway to heaven. There's a sign on the wall but she wants to be sure 'Cause you know sometimes words have two meanings. In a tree by the brook, there's a songbird who sings, Sometimes all of our thoughts are misgiven. Ooh, it makes me wonder, Ooh, it makes me wonder. There's a feeling I get when I look to the west, And my spirit is crying for leaving. In my thoughts I have seen rings of smoke through the trees, And the voices of those who stand looking. Ooh, it makes me wonder, Ooh, it really makes me wonder. And it's whispered that soon, if we all call the tune, Then the piper will lead us to reason. And a new day will dawn for those who stand long, And the forests will echo with laughter. If there's a bustle in your hedgerow, don't be alarmed now, It's just a spring clean for the May queen. Yes, there are two paths you can go by, but in the long run There's still time to change the road you're on. And it makes me wonder. Your head is humming and it won't go, in case you don't know, The piper's calling you to join him, Dear lady, can you hear the wind blow, and did you know Your stairway lies on the whispering wind? And as we wind on down the road Our shadows taller than our soul. There walks a lady we all know Who shines white light and wants to show How everything still turns to gold. And...
Words: 406 - Pages: 2
...white. Like Piper, many are looking to identify themselves but are disheartened by lurking stereotypes. All in all, it’s a problem society hasn’t overcome, but efforts such as Adrian Piper’s are educating and altering notions of the past. Piper’s racial identity issues, worsened by discrimination, began before her time when her father, a light skinned black man was placed in the segregated black army brigade only to be shunned by fellow troops men because they thought he wasn’t dark enough. As a result, Piper grew up to question her identity, not knowing where she belonged. However she later learned to defend her stance as a black woman, but along the way her enthusiasm was stifled by the constant “derogatory, insensitive behavior” she witnessed towards blacks whether they were around or not. In an effort to combat the racial discrimination, Piper turned to art as an outlet, and her photography not only helped her overcome her issues but also brought light to an overlooked societal issue. In 1972, Piper, in a series of images know as the Mythic Being progressively portrayed herself as a black man with a mustache, Afro wig, mirrored sunglass and cigar. In doing so she allowed herself to depict her own thoughts about how blacks are viewed, meanwhile getting whites and differently pigmented blacks to face the everyday stereotypes and racial injustice brought on by skin color. In a speech that coincides with her Mythic Being photography, addressed to her friends, Piper outlandishly...
Words: 942 - Pages: 4
...James Coates Mrs. Kopcak English May 10, 2006 Angels Angels were a major part of ancient civilizations, but how did the whole myth about angels start and has it changed over the years? How does the past compare to today’s world? Are there different classes of angels? What are their jobs, what do their jobs have them doing? The word 'angel' comes from the Greek angelos, which itself could be considered as a translation of the Hebrew word mal'akh, meaning 'messenger', suggesting that a being responsible for carrying messages between the human world and some other realm or realms of existence, someone who is an intermediary between 'down here' and 'up there'. The origins of angels, started back in ancient Sumeria. The Sumerian society is the oldest society that has left us clear evidence of the use of a winged human motif. This evidence is in the form of stone carvings, either in the form of three-D statues or relief carvings that provide the illusion of three-dimensionality. The religion of these people was complex, embracing a wide variety of spirits and gods, but of particular interest was their belief in 'messengers of the gods', angelic forces who ran errands between gods and humans. The Sumerians also believed that each person had a 'ghost' of some sort (what we would now probably label as 'guardian angel') with this entity remaining a constant companion for a person throughout their life. After the polytheistic Semitic tribes had conquered the Sumerians around 1900...
Words: 3083 - Pages: 13
...Market Report It was a quiet ending to a tumultuous week during which the benchmark S&P 500 lost 3.81 percent. The Nasdaq gave back 3.97 percent during the week. The Dow suffered a milder, but still substantial loss of 2.94 percent on the week. Even after the pullback during the week, the Dow is still positive by 1.89 percent on the year. The Nasdaq Composite has given back 3.03 percent during 2011. The S&P 500 has had the worst performance of the year among the majors, falling by 3.34 percent since December 31, 2010. The U.S. stock market is still likely to rise or fall in the short term depending on the latest headlines out of Europe. Hopefully some real progress will be made in Europe before bond yields in Spain and France spiral dangerously higher like they have already done in Greece and Italy. It was a big week for retailers’ earnings. Retailers Wal-Mart Stores, Inc. : Wal-Mart missed its third quarter earnings per share of $0.97 by $0.01 while its $109.5 billion revenues (a 8.2 percent year over year rise) beat estimates by $1.5 billion. Same store sales rose 1.3 percent, exceeding analyst forecasts of 0.3 percent. The company boosted its fourth quarter earnings per share to $1.42 – $1.48 and Bank of America Merrill Lynch reiterated its Buy Rating and Morgan Stanley gave it a Neutral Rating. The stock closed at $57.23 on Friday, up 0.88 percent. J.C. Penney : J.C. Penney’s reported an in-line third quarter earnings per share of $0.11 and a $4.0 billion...
Words: 651 - Pages: 3
...1. reparation and planning:- Dean Markin had engineered an organizational change that moved Dr. Forester from one department to another. There was an ideological difference among all the players in this scenario. 2. Definition of ground rules:-In Mr. Markin´s officethere will take place a meeting where both parts will expose their points of view like in a debate, both oarties have to respect each others time to speak and listen carefully. 3. Clarification and justification:- Both parties will show evidence, 4. Bargaining and problem solving :- Dr. Marino was in a difficult situation. However, the frustration expressed by Dr. Forester had not yet escalated to a complex or crisis situation. Careful preparation would be essential for a follow-up conversation and continu- ing reinforcement of the balance between Dr.Forester’s expectations and departmental expec- tations. These conversations should demonstrate a positive attitude, be brief and clear, and acknowl- edge Dr. Forester’s past accomplishments and fu- ture value. 5. Closure and Implementation:- Dr. Marino should have considered the benefits or problems that may evolve from the following possible outcomes: Dr. Forester may resign. – Dr. Forester may circumvent Dr. Marino and petition Dean Markin for support. – Promotion and tenure guidelines may change.The expectations of the leadership, the faculty, and the faculty managers must be clear to all parties so that the sources of conflict will be minimized. The...
Words: 279 - Pages: 2
...Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to decide. Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to decide. Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to decide. Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to decide. Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to decide. Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to decide. Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to decide. Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to decide. Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to decide. Peter piper picked a pickled pepper. It was not a very good pepper but it got the job done. What job you may ask? I will leave that for you to...
Words: 385 - Pages: 2
...After a near-death experience one might think “What doesn’t kill me makes me stronger.” What they should be thinking about is what got them into a near-death situation in the first place. Several years ago I had been working in Europe for more than 200 days straight. I was sick of the cold, dreary weather I was forced to endure day in and day out in the north of England. So when my friends suggested that I join them on vacation to go scuba diving in the Cayman Islands, I jumped at the chance to go. What I didn’t know at the time was that I would learn a valuable lesson - to trust my instincts and not to give into peer pressure. The first day on the island we went to one of the many dive shops that dotted the harbor along the port town of Stingray City. Although we were able to book three days of diving, we had to wait until the next day to make our first dive. We were all anxious to do something after the long plane ride. My friend Rex suggested that we go snorkeling in the coral reefs off of Seven Mile Beach. Personally, I thought that it was a bad idea. I was not a really strong swimmer, and we would be alone without a boat to pick us up if we got tired. But Rex and his brother Doug would not let go of the idea and pressured me into going, and against my better judgment I agreed to go. The turquoise blue water of the Caribbean Ocean was warm and calm. I was surprised by the gentle slope of the seabed and how far we were able to walk out before we...
Words: 800 - Pages: 4
...current maintenance abilities is that it also acts as inventory management. This complicates the procedures and provides a lot of extra overhead to the application they do not desire. A good maintenance ability for them may consist of only 2 parts: 1) a log of procedures performed on each aircraft and 2) display a schedule, similar to the flight schedule, of when procedures will need to be done next for each aircraft. Deliverables • An ERD that solves the problems above • An Access Database that implements the ERD w/ sample data • Saved SQL queries that demonstrate usage of your DB • Documentation/presentation that summarizes your ERD/experiences Deeper Insight to the Flight Schedule Composite Key: PA-28 161 N281HG: • PA – refers to Piper Aircraft, a manufacturer - http://www.piper.com/ • 28 – is a family of light aircraft produced by PA https://en.wikipedia.org/wiki/Piper_PA-28_Cherokee • 161 – the variant of the family (aka Warrior) • N281HG – The tail number Other aircraft in the schedule • Arrow - http://www.piper.com/aircraft/trainer-class/arrow/ • Archer -...
Words: 335 - Pages: 2
...current maintenance abilities is that it also acts as inventory management. This complicates the procedures and provides a lot of extra overhead to the application they do not desire. A good maintenance ability for them may consist of only 2 parts: 1) a log of procedures performed on each aircraft and 2) display a schedule, similar to the flight schedule, of when procedures will need to be done next for each aircraft. Deliverables • An ERD that solves the problems above • An Access Database that implements the ERD w/ sample data • Saved SQL queries that demonstrate usage of your DB • Documentation/presentation that summarizes your ERD/experiences Deeper Insight to the Flight Schedule Composite Key: PA-28 161 N281HG: • PA – refers to Piper Aircraft, a manufacturer - http://www.piper.com/ • 28 – is a family of light aircraft produced by PA https://en.wikipedia.org/wiki/Piper_PA-28_Cherokee • 161 – the variant of the family (aka Warrior) • N281HG – The tail number Other aircraft in the schedule • Arrow - http://www.piper.com/aircraft/trainer-class/arrow/ • Archer -...
Words: 335 - Pages: 2
...Adrian Piper is an American conceptual artist and analytical philosopher. Her work addresses ostracism, racism, social identity, and gender. She has produced an exceptionally impressive body of work spanning from a period of over thirty years. She has played a formative role in the emergence of conceptual art in the 1960s and 1970s and even more crucial role in the development of identity based art in the 1980s and 1990s. Piper produces artwork in a variety of traditional and nontraditional media, such as photo-text collage, drawings on pre-printed paper, paintings, video installations, sculptures, performances, and sound works. She is an extraordinary artist that is very passionate and socially engaged as she has mentioned, “ I love thinking about aesthetic issues, the organization of line and form in space—that is never very far from me—but I want to speak to everyone, not just the art world. I want to keep my eyes on the big issues, the issues that are going to take centuries to solve, that really plague people all the time…For me the biggest problem, the most...
Words: 481 - Pages: 2
...Demonstrated through certain clothing choices, peculiar habits, and specific quirks, Arnold Friend's character from Joyce Carol Oates' "Where Are You Going, Where Have You Been?" represents Charles Schmid, also known as the "Pied Piper of Tuscon," a serial killer responsible for the disappearances and murders of Alleen Rowe, and Gretchen and Wendy Fritz. According to the NY Daily News article, "Justice Story: Pied Piper of Tuscon" by Mara Bovsun, Schmid "was a little pipsqueak of a guy, standing just about 5'3'' tall" (Bovsun). To combat his height disadvantage, Schmid would wear boots and stuff them to make him appear taller; one could imagine that walking in his shoes wouldn't have been the most pleasant experience. This parallels to how...
Words: 314 - Pages: 2
...My most proud moment at Piper High School was being invited to do Dual Enrollment with the University of Florida. I remember it as if it was yesterday. Eyes darting to and fro, palms sweating, there I sat hunched over in the corner of Mrs. Chin’s classroom. It was about my third month at Piper and I didn’t have any friends just yet, so I sat alone. I had recently migrated from Jamaica and was trying my best to get accustomed to the new school system. Hence, I would constantly scan the classroom to try and absorb any information that was offered on a chart, or paper, or book. Suddenly, my eyes got fixated on a poster advertising sat tutoring. The words were in bold and capitalized so it seemed to be important. I started wondering if this SAT thing was like a test, or was it a program? Did I need to take it?...
Words: 705 - Pages: 3
...Project Management Email-Piper Industries OPS 571 Dear Mr. Gritsch, I would like to thank Piper Industries for allowing our team to analyze your projects. Our team has carefully reviewed all three projects for a best fit to your business needs. Included you will find our analysis and recommendations of the Project Proposal that most benefits your company. Based on the review of the three projects, it appears that the Juniper project which is an enhancement of a current widget being offered will not be profitable option. It requires a cost of $350,000 to bring the product to market with a ROI of 76.9% of the initial cost at its 3 year life span. With advancements in technology ending the life of this product, it is recommended not to pursue this project. The Palomino project may appear to be more attractive with enhancements using existing technology. Upon reviewing the figures, $655,000 start-up costs to bring to market and a predicted $90,000 return each year for 7 years and factoring a ±5% margin, this project takes a different spin that presents a risk of loss to the organization. With a potential -5% (-$31,500) ROI, it becomes obvious that this project is not worth the risk. The ideal project that our team recommends is the Stargazer project. With an initial research and development cost of $450,000, it will only require an additional $125,000 to bring this product to market. Factoring a product life forecast of 7 years, your organization...
Words: 636 - Pages: 3