Hence Mann et al., proposed a hypothetical, predictive stress-diathesis model in which the risk for suicidal actions is not only due to a proximal stressor/risk factor most likely acute episode of psychiatric illness but also a distal stressor/risk factor likely a diathesis. Research on the elements of the diathesis for suicidal behavior is relatively new. Melhelm et al (Melhem NM, Brent DA 2007) in a prospective study demonstrated that diathesis for suicide is partly heritable and has familial transmission across offsprings. As proposed by Mann, elements of the diathesis include aggressive impulsive traits, hopelessness, more severe suicidal ideation and subjective depression in depressive episode and cognitive inflexibility. The important