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Prefrontal Cortex Case Study

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The prefrontal cortex (PFC), located in the frontal lobe, is a core neutral system controlling rightful decision-making and the suppression of impulsive behaviour. It is therefore a key area when considering antisocial behaviour (ASB) such as psychopathic tendencies, alcoholism and aggression. This includes ‘rule breaking behaviour that is central to criminal, violent and psychopathic individuals’ (Raine and Yang 2006). Thus, in this essay I will assess the importance of the link between damage to the PFC and ASB and perhaps its significance in relation to neuroethics and the legal system. Meanwhile, others remain sided towards the argument that it is environmental risk factors and gene abnormalities that lead to cognitive, emotional and behavioural abnormalities, which in turn predispose ASB.

Support for the link between dysfunction to the PFC and ASB is derived from brain imaging studies carried out on affective murderers and …show more content…
This view suggests that aggression is produced in the brain. In 1848 an iron bar went straight through the front of his brain, which resulted in damage to the PFC. Drastic personality changes were reported such as being disrespectful yet his intellectual and physical recovery was normal. As Gage’s friends famously articulated, “Gage is no longer Gage” (Dean Mobbs, Hakwan C. Lau, Owen D. Jones, Christopher D. Frith 2007). This case study shows the importance of the brain in shaping personality, especially the significance of the PFC. Although this study allows access to a rich source of information, the data is unique. There are weaknesses with adopting an idiographic approach, as one cannot be sure whether results from one human will generalise elsewhere, as everybody responds in different ways. Moreover, one cannot claim causality between the accident and the personality change as there could be intervening, unknown variables

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