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ORIGINAL ARTICLE

JK-PRACTITIONER

Abstract: The study was carried out on 88 patients of infertility irrespective of duration, type or cause. The patients were seen in the OPD of Obstetrics Hospital at Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar (SKIMS). A detailed history was taken and routine examination was done. All expensive and invasive investigations were deferred and patients were put on 5mg of folic acid and 100mg of Vitamin B6 daily. It was found that 62 patients (70.45%) conceived within 4 months of treatment. Conception rate was more in primary infertility cases (76.39%), than in Secondary infertility cases (43.75%). Likewise conception rate was more in younger age group with marital life of 2-3 years. Key Words: Infertility, Primary infertility, Secondary infertility, Folic acid, Vitamin B6. JK-Practitioner 2002; 9(4): 242-243

Inability of a couple to conceive after one year of unprotected coitus with adequate coital frequency is labelled as infertility. It is a common cause for consultation with both the general practitioner and specialist affecting one in six couples. 80-90% of fertile couples will achieve a pregnancy within one year of trying and 95% within 2 years. Aetiology is usually multifactorial and varies with the duration of infertility. Aetiology at an early stage includes unexplained infertility (3 0%) (really delayed normal fertility); male factors (25%) (single most common defined cause); ovulatory failure (20%); tubal damage (15%) and endometriosis (5%). Childlessness can be tragic to the married couple and most of the times a cause for marital di replication.3 DNA synthesis in endometrial stromal cells is required for implantation4 and deficiency of folic acid may lead to subclinical abortion before a pregnancy is diagnosed.

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