...is in the early innings of an innovation cycle with many labelexpansion opportunities and novel agents in phase 2 or 3 trials that are largely unaccounted for in Street models. Hence, we are bullish on the group for 2014. Please join us for a call today at 11am ET to discuss our sector outlook/favorite names (US dial-in: 888-889-1309; OUS: 773-756-0161; Passcode: BIOTECH). Large-cap biotech: We don’t believe that a strict assessment of P/E multiples accurately addresses the nuances of the sector (2014e – Biotech: 22x vs. S&P 500: 15x). In our view, large caps are poised for an inflection point in revenue growth over the next two years, driven by significant drug launches in major therapeutic categories. Some of these include Gilead’s Sovaldi in hep C, Biogen’s...
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...Interferon drugs (a protein used in immune to virus reproduction intervenes) such as Pegasys and Pegintron. Protein protease blocker (protease inhibitor) that interfere with the replication of the virus such as: Sofosbuvir (Sovaldi), Olysio (Simeprevir), Victrelis (Boceprevir) and Incivek (Telaprevir). As well as polymerase inhibitor drugs such as Exviera (Dasabuvir). Unlike the previous generation hepatitis C drug that is done by injection into the patient once a week, now patients only need to take one pill every day for 3-6 months depending on the patient's heart condition and types of the virus. A cure rate of these medicines is also quite high at 98-100 percent. Sofosbuvir administration period is 12 to 24 weeks at a dose of 400 milligrams per day. The side effects is fairly mild, such as insomnia, anemia, headache, and vomiting. Taking care of...
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...Anti-Cancer Drug Cost Regulations- Cost-Containment for the Pharmaceutical Companies Brenda Roberson University of Maryland University College Abstract Drug development is a long, inefficient, and expensive process and takes 10 to 15 years for development at a cost of about $1.3 billion (Nelson, 2014). When speaking of research and development (R&D) for new drugs; a large number of drugs that go through research do not make it to the FDA or the marketplace. Critics of pharmaceutical companies point out that only a small portion of the pharmaceutical companies’ expenditures account for research and development (R&D). The majority of the money’s spent in marketing and administration. There is also controversy over the $1.3 billion figure as an actual cost. Reported by Nelson (2014) Dr. Kantarjian of M.D. Anderson disputes the $1.3 billion figure for development; he believes this figure to be inflated to cover ancillary expenses, salaries, bonuses, stock market returns, and other indirect costs not related to R&D. The cost of cancer drug therapy is becoming impossible to justify or rationalize for both patient and society. New cancer drugs being approved by the Food and Drug Administration (FDA) are typically costing upwards of $100,000 per year and many times used in combination with other agents (Bunnell, 2012, p. 932) increasing the cost even more. These high priced anti-cancer drugs achieve only marginal benefit for the patient. Benefits achievements of...
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...Key Issues & Economic Pressures Impacting the Pharmaceutical Industry in 2015 Presented to: Dr. Siamack Shojai Economic Analysis 6090, William Paterson University December 15th, 2015 The pharmaceutical industry has experienced tremendous growth over the past few decades, with a substantial change in the market dynamic from a provider, healthcare plan & patient perspective. Medical advancements coupled with research & development efforts have expanded the product base in terms of a variety of new treatments across numerous therapeutic classes. As depicted in the illustration below, the total global pharmaceutical sales reached $1,057,000,000 in 2014; based on the past 10 years we can expect the forecast to show a similar increase over the next few years. IMS Health Market Prognosis, May 2015 Of all the changes visible within the pharmaceutical market, there are a few that are truly revolutionizing the market: US healthcare reform, emergence of specialty product markets, price strategy & mergers & acquisitions. The healthcare market has changed under Obama, opening healthcare coverage to more patients & bringing forth treatment & medication to a larger population. The emergence of specialty products pose an entirely new challenge to the market in terms of the doctor’s prescribing habits, healthcare plan coverage & out-of-pocket cost to the patient. This along with other economic pressures brings an entirely new perspective to pharmaceutical...
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...‘ Health Care Delivery Systems Issue Report: Cost of Prescription Medications Jill Stanley Seattle Pacific University Health Care Delivery Models NUR 4944 July 19, 2014 Most everyone knows that the United States has the leading role when it comes to health care spending and pays out almost one thousand dollars per person per year on pharmaceuticals (Paris, 2014). Sadly, while the financial burden is high for the average family, many Americans are not taking their recommended medications because of the high costs. One in five Americans skip doses because of the cost (Paris, 2014). While there are many things nurses can do to enhance prescription medication compliance, understanding costs and helping implement ways in which patients can control costs, while promoting better outcomes, is critical. The United States spends almost 800 dollars a unit per population on prescription drugs, more than any other country and almost twice the average of 401 dollars per capita (OECD), (Ginsburg et al., 2009, p. 28). Prescriptions account for 17% of all privately insured health care costs and 25.4% of out of pocket spending according to Health Care Cost and Utilization Report (HCCI): 2011. Brand name or patented drugs have increased in price by 17.7% from 2010 to 2011 and generic drugs have actually decreased in cost by -7.2% for the same years from the same HCCI report. Generic drugs have had an increase in utilization from consumers’ while brand name has decreased and this...
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...of testing and interpretation of results. o Information about medical management and long-term care: < How to select candidates for antiviral therapy. < Importance of liver-cancer screening. < When to refer patients to a specialist.” The strategy of educational programs of Hep C should be used globally to reduce the risk of spreading the virus and to prevent further infections by treating all that are infected with HCV. Early treatment of Hep C saves the expensive complications of the future such as cirrhosis, liver transplant, or liver cancer. Treatment Hep C has over 90 percent cure rate, however the newer medication is very costly. The pharmaceutical company Gilead Sciences Inc. of Foster City, California produces it. “The new drug Sovaldi costs $1,000 per pill. A typical course of treatment will last 12 weeks and run $84,000, plus the cost of necessary companion drugs. Some patients may need treatment for twice as long.” The cost is out of reach for most that are infected and not all of the insurance companies cover the medication. The Hepatitis Foundation International (HFI) is a leading organization working for access to treatment for millions. “The Hepatitis Foundation International (HFI) is a 501 (c) 3 non-profit organization established in 1994 with world headquarters located in Silver Spring, MD. Since its inception, HFI has worked on eradicating chronic hepatitis by promoting and advocating for health and wellness.” HFI’s mission is to educate, prevent, support...
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...Page No. 2 Index Swachh Bharat Mission FEB & MARCH, 2015 AUGUST, 2012 Page No. 4 Insurance Sector In India Page No. 5 Bharat Ratna Award Designed by: Chandan Kumar “Raja” For Advertisement Contact at : 9958790414 Join us at Facebook: https://www.facebook.com/iasexamportal Follow us at Twitter: https://twitter.com/iasexamportal CURRENT AFFAIRS National Issues International Issues India & the World Economy Science and Technology Sports Awards & Prizes In The News 6 14 20 23 39 51 58 64 Disclaimer: Editor and Publisher are not responsible for any view, data, figure etc. expressed in the articles by the author(s). Maps are notational . All Disputes are subject to the exclusive jurisdiction of competent courts and fourms in Delhi/New Delhi only. Selected Articles from Various Newspapers & Journals Page No. 67 91 Cyberspace Page No. 93 Regional Rural Banks The Mauryan Empire Model Paper G.S. Paper I 94 117 Join Online Coaching For IAS Pre & Mains Exams http://iasexamportal.com/civilservices/courses Project Mausam and Maritime Silk Route SWACHH BHARAT MISSION Throughout the world around 2.5 billion people do not have toilets to use, out of those 250 crore people 65 crore live in India alone. In order to solve this big challenge government of India has launched “Swachh Bharat Mission” on the birth anniversary of Mahatma Gandhi and former Prime Minister Lal Bahadur Shastri...
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