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Research paper on Stem Cell Research Legislation and the related legal issues: What is the history of Stem Cell Research Legislation in the United States? How does it compare to comparable statutes in the rest of the world? In this paper talk about what the current legislative state of affairs is and where the law on stem cells in the United States should go in the future and why. Make sure you use ample research and cited sources to support your arguments but make sure to state your own opinion on the issues as well.
Stem Cell Research TJ AS OF:
2/4/2009--Introduced.
Stem Cell Research Improvement Act of 2009 - Amends the Public Health Service Act to require the Secretary of Health and Human Services to conduct and support research that utilizes human embryonic stem cells, regardless of the date on which the stem cells were derived from a human embryo. Limits such research to stem cells that meet the following requirements: (1) the stem cells were derived from human embryos donated from in vitro fertilization clinics, were created for the purposes of fertility treatment, and were in excess of the needs of the individuals seeking such treatment; (2) prior to donation, it was determined that the embryos would never be implanted in a woman and would otherwise be discarded; and (3) the individuals seeking fertility treatment donated the embryos with written informed consent and received no financial or other inducements.
Requires the Director of the National Institutes of Health (NIH) to issue guidelines on research involving human embryonic stem cells. Authorizes the Director to issue guidelines on research involving other human stem cells, as scientifically warranted. Provides for updates of guidelines under this Act. Directs the Secretary to take into consideration guidelines on human stem cell research developed by nationally- and internationally- recognized scientific organizations.
Requires NIH research to comply with guidelines under this Act.
Requires the Director to: (1) determine the extent to which the guidelines under this Act apply to research on human embryonic stem cells derived before the effective date of such guidelines; and (2) include in its biennial report to Congress a summary of research activities on human stem cells.

http://thomas.loc.gov/cgi-bin/bdquery/D?d111:872:./list/bss/d111HR.lst:@@@L&summ2=m&|TOM:/bss/111search.html|
The Congress finds as follows:
(1) On March 9, 2009, President Barack Obama issued Executive Order 13505, entitled `Removing Barriers to Responsible Scientific Research Involving Human Stem Cells'.
(2) On July 7, 2009, the National Institutes of Health issued guidelines on human stem cell research.
(3) The scientific field of stem cell research is continually advancing.

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| | | | | You are here: Popular Issues >> Pros And Cons Of Stem Cell Research Pros and Cons of Stem Cell Research - What are Stem Cells?
There has been much controversy in the press recently about the pros and cons of stem cell research. What is the controversy all about? "Stem" cells can be contrasted with "differentiated" cells. They offer much hope for medical advancement because of their ability to grow into almost any kind of cell. For instance, neural cells in the brain and spinal cord that have been damaged can be replaced by stem cells. In the treatment of cancer, cells destroyed by radiation or chemotherapy can be replaced with new healthy stem cells that adapt to the affected area, whether it be part of the brain, heart, liver, lungs, or wherever. Dead cells of almost any kind, no matter the type of injury or disease, can be replaced with new healthy cells thanks to the amazing flexibility of stem cells. As a result, billions of dollars are being poured into this new field. Pros and Cons of Stem Cell Research - Where Do They Come From?
To understand the pros and cons of stem cell research, one must first understand where stem cells come from. There are three main sources for obtaining stem cells - adult cells, cord cells, and embryonic cells. Adult stem cells can be extracted either from bone marrow or from the peripheral system. Bone marrow is a rich source of stem cells. However, some painful destruction of the bone marrow results from this procedure. Peripheral stem cells can be extracted without damage to bones, but the process takes more time. And with health issues, time is often of the essence. Although difficult to extract, since they are taken from the patient's own body, adult stem cells are superior to both umbilical cord and embryonic stem cells. They are plentiful. There is always an exact DNA match so the body's immune system never rejects them. And as we might expect, results have been both profound and promising.

Stem cells taken from the umbilical cord are a second very rich source of stem cells. Umbilical cells can also offer a perfect match where a family has planned ahead. Cord cells are extracted during pregnancy and stored in cryogenic cell banks as a type of insurance policy for future use on behalf of the newborn. Cord cells can also be used by the mother, the father or others. The more distant the relationship, the more likely it is that the cells will be rejected by the immune system's antibodies. However, there are a number of common cell types just as there are common blood types so matching is always possible especially where there are numerous donors. The donation and storage process is similar to blood banking. Donation of umbilical cells is highly encouraged. Compared to adult cells and embryonic cells, the umbilical cord is by far the richest source of stem cells, and cells can be stored up in advance so they are available when needed. Further, even where there is not an exact DNA match between donor and recipient, scientists have developed methods to increase transferability and reduce risk. Pros and Cons of Stem Cell Research - Embryonic Cells
The pros and cons of stem cell research come to the surface when we examine the third source of stem cells - embryonic cells. Embryonic stem cells are extracted directly from an embryo before the embryo's cells begin to differentiate. At this stage the embryo is referred to as a "blastocyst." There are about 100 cells in a blastocyst, a very large percentage of which are stem cells, which can be kept alive indefinitely, grown in cultures, where the stem cells continue to double in number every 2-3 days. A replicating set of stem cells from a single blastocyst is called a "stem cell line" because the genetic material all comes from the same fertilized human egg that started it. President Bush authorized federal funding for research on the 15 stem cell lines available in August 2001. Other stem cell lines are also available for research but without the coveted assistance of federal funding.

So what is the controversy all about? Those who value human life from the point of conception, oppose embryonic stem cell research because the extraction of stem cells from this type of an embryo requires its destruction. In other words, it requires that a human life be killed. Some believe this to be the same as murder. Against this, embryonic research advocates argue that the tiny blastocyst has no human features. Further, new stem cell lines already exist due to the common practice of in vitro fertilization. Research advocates conclude that many fertilized human cells have already been banked, but are not being made available for research. Advocates of embryonic stem cell research claim new human lives will not be created for the sole purpose of experimentation.

Others argue against such research on medical grounds. Mice treated for Parkinson's with embryonic stem cells have died from brain tumors in as much as 20% of cases.1 Embryonic stem cells stored over time have been shown to create the type of chromosomal anomalies that create cancer cells.2 Looking at it from a more pragmatic standpoint, funds devoted to embryonic stem cell research are funds being taken away from the other two more promising and less controversial types of stem cell research mentioned above. Learn More Now!Footnotes
1 The Real Promise of Stem Cell Research Dr. David Prentice, HealthNewsDigest.com
2 Derivation of Human Stem-Cell Lines from Human Blastocysts, C. A. Cowan and others. March 25, 2004, New England Journal of Medicine, p.1355 with secondary reference to footnotes 13-17 p.1356.http://www.allaboutpopularissues.org/pros-and-cons-of-stem-cell-research.htmLike this information? Help us by sharing it with others using the social media buttons below. What is this?Share Us: 368Share | |
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http://www.experiment-resources.com/stem-cell-pros-and-cons.html
All scientists must consider whether the positive effects from their research are likely to be significantly higher than the negative effects.
WHAT ARE STEM CELLS?
Stem Cells are crucial to develop organisms. They are non-specialized cells which have the potential to create other types of specific cells, such as blood-, brain-, tissue- or muscle-cells.

Stem cells are in our body all our lives, but are far more potent in a fetus than in an adult body.
Some types of stem cells may be able to create all other cells in the body. Others have the potential to repair or replace damaged tissue or cells.
Embryonic Stem Cells are developed from a female egg after it is fertilized by sperm. The process takes 4-5 days.
WHAT IS STEM CELL RESEARCH?
Stem cell research is used for investigation of basic cells which develop organisms. The cells are grown in laboratories where tests are carried out to investigate fundamental properties of the cells.
Aborted fetuses are not the only source of stem cells

There are stem cells in the both placenta and blood contained in the placenta. Also the primary source of stem cells is from blastocysts. These are fertilized human eggs that were not implanted into a woman.
The controversy surrounding stem cell research led to an intense debate about ethics. Up until the recent years, the research method mainly focused on Embryonic Stem Cells, which involves taking tissue from an aborted embryo to get proper material to study. This is typically done just days after conception or between the 5th and 9th week.
Since then, researchers have moved on to more ethical study methods, such as Induced Pluripotent Stem Cells (iPS). iPS are artificially derived from a non-pluripotent cell, such as adult somatic cells.
This is probably an important advancement in stem cell research, since it allows researchers to obtain pluripotent stem cells, which are important in research, without the controversial use of embryos.
There were two main issues concerning stem cell research with both pros and cons: 1. How the knowledge will be used 2. Concerns about the methods
The first issue is really not just about stem cell research, as it may be applied to most research about human health.
Since 2007, the second point, concerns about the methods involved, has been less debated, because of scientific developments such as iPS.
1) STEM CELL RESEARCH - ARGUMENTS REGARDING THE USAGE OF THE KNOWLEDGE
As you will most probably notice, the following arguments are not exclusively in use when talking about stem cell research.
Pros
Stem cell research can potentially help treating a range of medical problems. It could lead humanity closer to better treat and possibly cure a number of diseases: * Parkinson’s Disease * Alzheimer’s Disease * Heart Diseases, Stroke and Diabetes (Type 1) * Birth Defects * Spinal Cord Injuries * Replace or Repair Damaged Organs * Reduced Risk of Transplantation (You could possibly get a copy of your own heart in a heart-transplantation in the future * Stem cells may play a major role in cancer
Better treatment of these diseases could also give significant social benefits for individuals and economic gains for society
Cons
* "We should not mess with human life." * "Humans should not be trying to play God" * Some argue that stem cell research in the far future can lead to knowledge on how to clone humans. It is hard to say whether this is true, but we have seen devastating consequences of other research-programs, even with good intentions, such as nuclear research.
2) STEM CELL RESEARCH - PROS AND CONS ABOUT THE METHODS INVOLVED
The controversy regarding the method involved was much tenser when researchers used Embryonic Stem Cells as their main method for stem cell research.
DISCLAIMER:
These points are based on the old debate about the methods of stem cells research, from before 2007. Since then, scientists have moved on to use more ethical methods for stem cell research, such as IPS. This section serves as an illustration of the difficult evaluations researchers may have to analyze.
Pros before 2007 * "The benefits of stem cell research have such a great outcome that they outweigh the ethical issues." (Cost-benefit-analysis) * "If someone is going to have an abortion, isn’t it better that we use it for something useful?" * Adult stem cells would not be that interesting because they do not have the same properties as stem cells from a fetus. * The research would give great insights about the basics of the body.

Cons before 2007 * Critics against stem cell research argued that the ethical issues of scientific work on aborted fetuses did not justify the possible benefits. * "A life is a life and that should never be compromised. A fertilized egg should be valued as a human life even if it is in its very first weeks. Destroying human life in the hopes of saving human life is not ethical." * We should (and will) develop more ethical methods (such as using adult stem cells) which will enable us to research ethically. We should wait until those methods are available. * The scientific value has been overstated or has flaws. E.g. we do not know for sure that we can use stem cells to clone transplantable organs.
CONCLUSION
The stem cell-research is an example of the, sometimes difficult, cost-benefit analysis in ethics which scientists needs to do. Even though many issues regarding the ethics of stem cell research have now been solved, it serves as a valuable example of ethical cost-benefit analysis.
The previously heated debate seems to have lead to new solutions which makes both sides happier.
Stem Cell pros and cons had to be valued carefully, for a number of reasons.
When you are planning a research project, ethics must always be considered. If you cannot defend a study ethically, you should not and will not be allowed to conduct it. You cannot defend a study ethically unless the presumed cost is lower than expected benefits. The analysis needs to include human/animal discomfort/risks, environmental issues, material costs/benefits, economy etc.
Why was the debate regarding the stem cell research so intense?
First, it was a matter of life - something impossible to measure. And in this case, researchers had to do exactly that: measure life against life.
Both an abortion and someone dying, suffering from a possible curable disease, is a tragedy. Which have the highest value? Does a big breakthrough in the research justify the use of the method in the present?
Would the benefits of studying abortions outweigh the costs? The choice was subjective: Nobody knows all the risks or all the possible outcomes, so we had to value it with our perception of the outcome. Perception is influenced by our individual feelings, morals and knowledge about the issue.
Second, at the time we did not know whether the research was necessary and sufficient to give us the mentioned health benefits.
Third, other consequences of the research are uncertain. Could the research be misused in the future or not? We simply do not know. All knowledge acquired, within research or other arenas, may be used for evil causes in the future - it is impossible to know.
The Stem cell research-debate is an example on how people value various aspects differently. It is also an example of how critics and debate can lead to significant improvements for both sides.

Read more: http://www.experiment-resources.com/stem-cell-pros-and-cons.html#ixzz1GESlFMId
Stem Cell Treatments
The XCell-Center treats patients with their own autologous adult stem cells. It is the first private clinic worldwide to hold an official license for the extraction and approval of stem cell material for autologous treatment.
Therapy focuses on stem cell treatment of cerebral palsy, spinal cord injuries, diabetes mellitus (types 1 and 2 as well as sequelae) and neurological diseases/disorders such as Parkinson's and stroke. Further indications include multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and Alzheimer's as well as arthritis, heart disease, and eye diseases such as macular degeneration.
Advisory board
Learn more about the XCell-Center's Scientific Partners.
Treatment Disclaimer
It is important to understand that while stem cell therapy can help alleviate symptoms in many patients and slow or even reverse degenerative processes, at times it does not work for all patients. Consequently, the XCell-Center can neither predict nor guarantee success for individual patients who undergo stem cell treatment.
Based on additional information, patient's current health situation and/or unforeseen health risks, the medical staff can always, in the interest of the individual patient, propose another kind of stem cell transplantation or in exceptional situations cancel the stem cell treatment at the XCell-Center.
For children to undergo stem cell therapy at the XCell-Center, both parents signatures are required. http://www.xcell-center.com/?gclid=CMPS2vf96acCFUvd4Aod6hsUcQ
Oklahoma moves towards outlawing embryonic stem cell research
28 February 2011
By Julianna Photopoulos
Appeared in BioNews 597
Legislation banning embryonic stem cell research in Oklahoma, United States, was approved by the state's House Committee last week. The House of Representatives' Public Health Committee narrowly passed the bill by six votes to five and it is now scheduled to go before the full House of Representatives.

The proposals would prohibit research which results in the destruction of the embryo and would also make it illegal to 'buy, sell, receive, or otherwise transfer' an embryo for such purposes. Transferring an embryo to be used in IVF would, however, be excluded from the restrictions.

'This legislation simply makes it illegal to create unborn children with the intent of killing them for research purposes', said the bill's author, Representative George Faught. 'Oklahoma can be pro-life, pro-research and pro-cure without endorsing embryo destruction', he said.

Faught said that 'embryonic stem cell research has not produced a single treatment and typically generates cancer tumours, not cures'. Instead, he supports adult stem cell research which he said 'is already helping patients overcome more than 70 diseases and disorders and does not require embryo destruction'.

The legislation states that the destruction of human embryos 'raises grave moral, ethical, scientific, and medical issues that must be addressed'. It says 'the moral justification for medical or scientific research cannot be based upon the dehumanising and utilitarian premise that the end justifies any means'.

In opposition to the proposals, Representative Doug Cox, a physician and Committee member, said: 'Embryonic stem cell research is extensively regulated under federal laws, as well as guidelines from national scientific academies. There is no need for state intervention'.

'Legislation outlawing such research in Oklahoma should fail if legislators are adequately informed of the facts, not misconceptions', he added.

The Oklahoma Legislature consists of two houses, the House of Representatives and the Senate, with 101 and 48 members accordingly, all elected directly by the people. In order for the bill to become law, both houses must agree to identical versions of the bill. After approval by both houses, the bill is sent to the Governor of Oklahoma who makes the final decision.

Former Governor of Oklahoma and Democrat, Brad Henry, vetoed a similar bill in the Republican-controlled legislature in 2009. The Oklahoma House voted to override the veto, but supporters of the bill were unable to get the two-thirds majority needed to do so. SOURCES & REFERENCES Bill Information for HB 1442 | Oklahoma State Legislature | 23 February 2011 | Embryonic stem cell research holds promise | NewsOK.com | 12 February 2011 | Lawmakers Vote to Ban Creation of Embryos for Experiments | Oklahoma House of Representatives Media | 22 February 2011 | Oklahoma Governor's Veto Of Stem Cell Bill Sustained | Newson6.com | 23 April 2009 | Oklahoma House committee passes measure to outlaw embryonic stem cell research | NewsOK.com | 23 February 2011 | Oklahoma House of Representatives - 2009 Session In Review | Oklahoma House of Representatives | | Oklahoma legislature | Wikipedia | 16 February 2011 |

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... Baylois Francois, Grass Kathleen, (2006) “Stem cell trials: Lessons from gene transfer research”, 23-26. When I first heard of stem cell research I wondered how the government could refuse Stem cell research, something that holds the cure for diseases like Alzheimer’s , Cancer or even HIV/AIDS. I didn’t know the background story and how stem cell research borders on the morality of what is ethical and what isn’t. Is it acceptable to save one life but kill another? The critics and the religious minded who believe life begins at conception see this as murder, while proponents praise it as innovative and groundbreaking, in helping save millions of lives. This Cutting-edge new experiment challenges and goes against numerous religions that oppose killing human life, which makes it so controversial. The issue of stem cell research largely involves the destruction of five to seven year old embryos, and raises the morality of this experiment. It questions our principals and makes us wonder are we really sacrificing a life or saving one? You have to choose between two wrong things. While there is immense excitement among scientists and people of the possibility of the millions of human lives stem cells can save there is also a great safety concern as well. Stem cell research has always been a very relevant topic. Over the last decade politicians, Scientists and theorists have debated on the medical advancement of stem cell research, its regenerative medicine and the remarkable...

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Stem Cell Research

...One of the most popular clinical studies being researched these days is stem cell transplantation. Until recently, moral issues of states and countries haven't allowed research to expound deeply into the unknowns. Within the last ten years though, scientists have made leaps and bounds in finding out concrete facts that this stem cell research has supplied. Tommy G. Thompson, Secretary of Health Services states, "I believe it will open up a world of opportunity for scientists, not only at the NIH, but elsewhere, because it demonstrates a cooperative atmosphere among academia, the private sector, and government that will allow us to move ahead" ("sign stem"1). New ways of conducting stem cell research have made the healing and repairing treatment for many diverse applications. To prove their point, scientists have broken down the basic facts of their studies throughout the last ten years. Embryonic stem cell transplantation is a related course of cells that are in charge of certain functions and systems of the body. The cells used in the transplantation process are contrived from "cryopreserved suspensions" from the fetal liver, thymus, bone marrow, spleen, brain, and the pancreas. Introducing these cells to the body can be approached in different ways. The first step taken is engrafting or multiplying cells in the affected area. These cells will then supplement missing or declining cells and replace/repair missing functions of the body. Production then commences with considerable...

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Stem Cell Research

...An understanding of the types, characteristics, and important benefits of stem cells Aids in understanding the ethical and social considerations of this controversy. There are Two main types of stem cells. One type, embryonic, uses the undifferentiated cells of an Early human embryo to create any new, specialized type of cell (Brignier and Gewirtz S337). Embryonic stem cells are very useful for cell based therapies because they can Develop into more than 220 cell types that are found in an adult, and they have the ability To reproduce in large numbers. They are capable of almost unlimited cell divisions when Placed in culture. This makes embryonic stem cells very flexible and versatile. Using Stem cells to learn about the ways that these cells differentiate, grow, and renew will also Have profound results in the study and cure of cancers, birth defects, diabetes, and spinal cord Injuries, and other diseases caused by dysfunctional cell replication. Research on 3 Embryonic stem cells can also improve drug safety, as a drug can be tested on a stem cell Line before use in a patient (Louis 2009). The embryonic stem cells are extracted from The inner cell mass during the early blastocyst phase of embryonic development. After an Egg is fertilized, generally during in vitro in the laboratory, it begins dividing. The Blastocyst is a hollow ball of about 150 cells. The inner cell mass are the cells located in The inner part of the ball, and once extracted, the embryo is no longer viable...

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Stem Cell Research

...WEEK 6: Stem Cell Research Legislation Course Project Abstract Stem cell research while very important in the medical field has and continues to be a source of controversy. Over the years legislation in the United States has gone back and forth over what is deemed acceptable and ethical as it pertains to this research. Due to recent legislation the ability exists to realize the potential of this research both in the United States and globally. It would be in the best interest of humankind for this research to continue with allowance and funding from the government. According to the National Institutes of Health Resource for Stem Cell Research: Stem cells have the potential to develop into many different cell types in the body during early life and growth. Stem cells are distinguished from other cell types by two important characteristics. First, they are unspecialized cells capable of renewing themselves through cell division, sometimes after long periods of inactivity. Second, under certain physiologic or experimental conditions, they can be induced to become tissue- or organ-specific cells with special functions. Given their unique regenerative abilities, stem cells offer new potentials for treating diseases such as diabetes, and heart disease. (n.d.) Although these cells have these unique capabilities to possibly save lives, they are also the center of much controversy surrounding their usage. The debate on the ethicality...

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Stem Cell Research

...Raymond Swayze Comp II In 2004, 7,266 blood stem cell donations and 1,126 cord blood units were provided in desperate need. More than 50,000 patients worldwide have received blood stem cells from an unrelated donor(WMDA). Different types of stem cells have the ability to heal many types of damaged human tissue. There’s only one type of stem cell that can almost guarantee it can fix any kind of tissue. This is known at the embryonic stem cell. The only way to obtain these cells is by taking them from the embryo, which will ultimately kill the embryo. To some people this is considered a form of abortion. This is such a hot topic because people have to choose to either save a current life, or kill a future life it. Of course there are two sides to every argument. One side is for it and one side is dead set against. Is the price of stem cells worth saving a life? In every opinion you form you must first realize how stem cell research works. The definition of a stem cell is an undifferentiated cell. This means the cell has no true function. Stem cells are placed along specialized cells. Specialized cells include, but not limited to the following, skin cells, muscle cells, or any other cell that plays a specific role in the human body. In the Multiple Scleroses disease the myelin protecting the neuron is missing. When myelin is missing there is constant pain. In a study in 1998 at the University of Wisconsin researchers gathered a group of mice that were genetically deficient...

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