...Re-absorption in the kidneys and associated abnormalities Task 1 Water is the main bodily fluid with around 60% of your body weight made up of water. This is a major component of bodily fluid. Bodily fluids contain many components within the body. they can include the following: Bile Mucus Sweat Blood serum Pleural fluid Urine Gastric juice Saliva Water This image shows the main electrolytes found within the bodily fluids. They are sodium, chloride, magnesium, calcium and potassium. They are involved in various functions in our cells and organs. They are responsible for maintain the balance of fluids between the intracellular and extracellular environments. Tutor vista 2014. List of electrolytes [Online] available from: http://chemistry.tutorvista.com/inorganic-chemistry/list-of-electrolytes.html...
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...Chronic glomerulonephritis which affects the glomeruli within the kidney and often impedes the kidneys’ function is known to be one of the most common causes of kidney failure. The development of chronic glomerulonephritis is often a blindside as there is little to no signs or symptoms of the disease. The development may occur due to many causes such as infections, immune diseases, blood pressure or diabetes. Patients’ are often diagnosed when the disease is severe or has been triggered by underlying causes. As many as 40% of people suffering from glomerulonephritis are on dialysis which shows how severe progression may escalate. Treatments are constantly being improved to make it for efficient for suffers such as plasmapheresis which are only...
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...10%-15% of body fluids. At this point, dehydration becomes a medical emergency. Jimmy was severely dehydrated and immediate steps were taken to rehydrate him. He was given intravenous fluids to restore his water and electrolytes that he had lost. What was happening in Jimmy’s body is that the osmolarity of his blood is higher than that of his tissues. This naturally causes water to be drawn from the cells and into the blood, since water follows a higher solute. (Where salt goes water follows.) The movement of water into the blood causes increases in blood volume, which increases blood pressure. Giving the blood enough pressure to pass though the glomerulus, the glomerulus is a capillary tuft surrounded by a Bowman’s capsule in the nephron of the kidneys. This is where your blood is filtered. If dehydration continues the tissues in the body start to die and the cells begin to shrivel. To maintain the homeostasis of the body’s water content or osmoregulation the body secretes a hormone called antidiurect hormone, ADH. ADH is secreted by part of the brain called the hypothalamus, located in an...
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...cases; 1 in 15 cases; 2 in13 cases; and _3 in five cases(LOW PERCENTAGE OF GLOMEROSCLEROSIS) | | Histopathologic Evaluation of Pretransplant Biopsy as a Factor InfluencingGraft Function After Kidney Transplantation: A 1-Year Observation | 92 | We observed a significant correlation between immediate graft function (IGF)and lack of ATN in the pre-0 biopsy. We observed no correlation between renal functionand arterial hyalinization and fibrosis, inflammatory infiltration, tubular atrophy. In thepostoperative period, we observed a significant correlation between IGF and lack ofinterstitial fibrosis with significantly lower levels of creatinine, urea, and potassium andhigher urine output early after transplantation. IGF and better function of the right kidneywas correlated with shorter time to reach a creatinine level of 2 mg%. In the postoperativeperiods, we also observed a difference between renal function depending on gender. Thepresence of acute tubular necrosis, arterial fibrosis, lack of inflammatory infiltration in thepre-0 biopsy correlated with worse late renal function. Among explantation biopsies 65.5%showed signs of CAN, and 37.93%, histologic marks of ARE.SEE TABLE 1( NOTICE presence of GS.correlate with IGF.no diff. in DGF or NGF between GS –ve and GS +ve. | | | Donor Biopsy and Kidney Transplant Outcomes: AnAnalysis Using the Organ Procurement andTransplantation Network/United Network for OrganSharing (OPTN/UNOS)...
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...Central University of Technology, Bloemfontein Early detection and prevention of Chronic Kidney Disease Contents page Definition of key terms used in the assignment Abbreviations used in the assignment Introduction Chronic Kidney Disease, a condition characterised by a gradual loss of kidney function. CKD is often misdiagnosed owing to the lack of knowledge about the disease. With early detection and prevention of the progression of the disease CKD patients can still enjoy life to the fullest while they manage their disease, however if the healthcare professionals fail to identify the disease on time the patient can suffer dire consequences. Besides the financial implications associated with the disease, there are the emotional implications together with physical and psychological. This assignment seeks to explore such implications in an effort to highlight the importance of early detection and prevention of kidney disease, with the best interest of the patient at heart Background Normal kidney anatomy http://doctorstock.photoshelter.com/image/I000096SqkYwaLhE The bean-shaped kidneys lie in retroperitoneal position in the superior lumbar region. Extending approximately from T12 to L3, the kidneys receive some form of protection from the lower part of the rib cage (E.N. Marieb, K Hoehn, 2010) The kidneys functions can be divided into two, non-excretory functions and excretory functions. Under excretory we have Glomerular filtration, Tubule...
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...Chronic Kidney Disease Ashley Oglesby Joyner Walden University Advanced Practice Care of Adults NURS-6531N-20 October 21st, 2017 Chronic Kidney Disease Chronic kidney disease occurs when there is a loss of nephrons which prevents perfusion, filtration and excretion. Chronic kidney disease is a debilitating disease that requires long-term treatment to improve the patient’s quality of life. Risk factors for kidney disease include high blood pressure, diabetes, exposure to renal toxic drugs, and systemic infections. Chronic kidney disease is diagnosed by patient history, physical exam, diagnostic testing, and laboratory studies. Management of chronic kidney disease involves frequent follow up appointments, routine blood work,...
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...her own once she is out of the bed with the assistance of a walker. Because of her obesity, Ms. C has several skin folds throughout her body, which make a great medium for fungal infections. The area underneath her skin folds is red and irritated. Ms. C has had oliguria for the past several days and is outputting very little to no urine. A foley catheter has been placed in order to remove any urinary retention. However, very minimal urine seems to be coming out of foley. The doctors have requested labs to be drawn on a regular basis to check her kidney function and to also monitor her electrolytes. Her admitting diagnosis is Acute Renal Failure. Past Medical History: o Essential Hypertension o Hyperlipidemia o Diabetes Mellitus Type 2 o Stage 3 Diabetic Chronic Kidney Disease o Severe Obesity Present Medical History: o Severe abdominal pain o Dehydration o Oliguria o Uncontrolled Diabetes o Chronic Kidney Disease o Hypertension o Obesity Active Orders: o Foley Catheter o Oxygen 2 L NC o Blood Sugar Monitoring AC and HS o Insulin Regular o Insulin NPH 10 units in AM o Insulin NPH 5 units before bed time o Flucanozole 100 mg IV o D5W 1000 mL with Sodium Bicarb 100 mEq IV solution running at 75 ml/hr o Albuterol 2.5 mg/0.5 mL Nebulizer 2.5 mg o Morphine Inj Syg 2mg PRN Q4H o Morphine Inj Syg 4 mg PRN Q4H o Lotrimin Cream o Ondansetron inj 4mg o Levothyroxine tab 175 mcg o Acetaminophen 650 mg o D50W Inj Syg o Glucagon Inj 1 mg o QVAR...
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...B3 Biology checklist | | |What You Need To Know |[pic] |[pic] |[pic] | | |D/C |Explain different types of behaviour: innate, courtship, habituation, imprinting and conditioning. | | | | | |B/A |Describe the work of different ethnologists helps to explain different types of behaviour. | | | | | |D/C |Explain that animals have different mating strategies that may (or may not) include parental care. | | | | | | |Describe the cost and benefits to parental care. | | | | | |B/A |Explain a range of mating strategies. | | | | | | |Explain parental care as an evolutionary strategy. | | | | | |D/C |Explain how animals use sound to communicate. | | | | | | |Explain how plants communicate with each other using chemicals. | | | | | |B/A...
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...Critical Pathway: Case Study of Chronic Renal Failure Advanced Pathophysiology NURS 5104 October 4, 2013 Critical Pathway: Case Study of Chronic Renal Failure I. Introduction Mr. P. J., a 38-year-old African American male, presented to the Emergency Department by the rescue squad team, with a six day old complaint of increased swelling of the bilateral lower extremities, unusual weight gain, and a feeling of ‘I can not breathe’ per patient. Patient was sent as a direct admit to the Intensive Care Unit (ICU) and placed on 2 liters NC with hydration and adult special care monitoring. Vital signs were taken by the paramedic enroute revealing the following: Ambulance Vitals: * BP 202/112 * Pulse 101 * Respirations 20 * O2 86% before O2 * Temp. 98.4 * Height 5’10 Patient stating * Weight 222 lbs. Patient stating (weighed the day before) The paramedic started a 20 gauge IV into Mr. J’s right antecubital and started him on 2 liters nasal cannula; due to the “presence of crackles no Procardia was administered” (J. Madden, personal communication, August 14, 2013). The paramedic monitored the vitals and reported to medical control the situation and estimated time of their arrival in five minutes. Mr. P. J. has been married to K for twenty years and they have one child, a twelve-year-old daughter. Mr. P. J. has worked in construction for twenty years; Mr. J stated working on his feet all day he noticed the swelling six days ago...
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...regimen. His B/P routinely runs in the range 155-165/92-102. His B/P today was 170/105. The client does not like to take pills and feels that they are not necessary. He also has been reluctant to modify his diet and likes to eat fried foods. He does not think his eating habits are causing any problems. Because of these symptoms, the client was admitted to the hospital for treatment and further evaluation. His lab values and renal studies confirmed the diagnosis of end stage kidney disease. Because of the severity of his problems, he was started on hemodialysis. What is the likely cause of his kidney failure? Explain your answers His kidney failure is caused by uncontrolled blood pressure and lack of treatment compliance. When you have uncontrolled high blood pressure it affects the kidneys because the blood vessels narrow and stiffen causing the nephrons in the kidney to work harder. Eventually if hypertension is left untreated it can lead to end stage renal disease because the nephrons in the kidney are no longer able to filter out the toxins such as nitrogen waste which builds up in the blood. They also are unable to maintain fluid or electrolyte balance. Eventually ESRD is demonstrated by decreased glomerular filtration rate less than 15mL/min. At first, the client refused the dialysis treatments. After further consultation with the medical team and his family, he agreed to start the treatments. List three common types of permanent access sites that can be used...
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...Abstract This paper will present with a patient’s case study revelations throughout her recent heath problems. It will discuss the patient’s underlying disease of diabetes mellulitiis. The six body systems affected by this disease will be discussed and the major pathophysiologic concepts within each system will be elaborated on. Our Patient’s Case Study Revelelations Our patient is a 62 year old female with cellulitis of her right lower leg. This patient has a history of smoking three packs a day for 40 years and unfortunately has admitted to smoking again. She has high blood sugar; however, she cannot remember the name of the medication she is taking for it. She has a “touch” of high blood pressure and claims she controls her hypertension by eating a low salt diet. Her husband passed away 14 years ago and she states that she misses him very much. As the weeks continue, our patient is experiencing dyspnea upon rising in the morning. She has bilateral diminished lung sounds along with crackles. Our patient’s condition continues to worsen and she is diagnosed with congestive heart failure. She is complaining of pain in her extremities and abdomen. Her lab work shows azotemia, red blood cells and protein in her urine, and elevated blood glucose level. The fluid buildup continues in her lungs and her urine output is minimal. Heart failure and fluid volume excess seems evident, as well as, her renal system appears to be impaired. Underlying Disease This patient’s...
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...results when there is a high level of sugar in the blood for an extended period of time. Diet, exercise, pills and insulin injections can control it. There are three main types of diabetes--Type I, which affects primarily the younger population; Type II, which primarily affects the population above 40; and gestational diabetes, which affects women during the third trimester of their pregnancy. While scientists do not know what causes diabetes, they do know that it is caused from a variety of factors that can vary from person to person. Examples of these factors are heredity, being overweight, and problems with beta cells, which are located in the pancreas. Diabetes can result in blurred vision, retinopathy, nerve problems, dry skin, and kidney issues. Diet plays a major role in the prevention of these problems. Sugar concentration in the blood is a major factor for diabetics, so understanding the sugar content of fats, proteins, and carbohydrates is essential. The goal from a diet perspective is to control your sugar in your bloodstream in such a way that the insulin in your bloodstream can manage it efficiently. In addition to diet, medication and exercise play a key role in controlling this disease. Currently, there is no known cure for diabetes. I believe that diabetes can be managed if the person follows a strict diet that is recommended by a nutritionist. DIABETES MELLITUS Diabetes Mellitus is a chronic disease where the blood in the body...
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...Communication, Homeostasis & Energy Communication & Homeostasis Outline the need for communication systems within multicellular organisms, with reference to the need to respond to changes in the internal and external environment and to co-ordinate the activities of different organs. Organisms need to respond to external stimuli, e.g. temperature, oxygen concentration and levels of sunlight. These may be over time, e.g. winter fur to summer fur, or quickly, e.g. changing size of pupils. Internal environments change too- the build up of carbon dioxide as a result of respiration changes the pH of the tissue fluid, and therefore inhibits enzyme activity. Multicellular organisms need to coordinate different organs, so this requires a good communication system which will: • Cover the whole body • Enable cells to communicate with each other • Enable specific communication • Enable rapid communication • Enable both short and long-term responses. State that cells need to communicate with each other by a process called cell signalling. State that neuronal and hormonal systems are examples of cell signalling. Define the terms negative feedback, positive feedback and homeostasis. Negative feedback- A process in which any change in a parameter brings about the reversal of that change so that the parameter is kept fairly constant. Positive feedback- A process in which any change in a parameter brings about an increase in that change Homeostasis- The maintenance of a constant...
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...Carrier Proteins and Active Membrane Transport The process by which a carrier protein transfers a solute molecule across the lipid bilayer resembles anenzyme-substrate reaction, and in many ways carriers behave like enzymes. In contrast to ordinary enzyme-substrate reactions, however, the transported solute is not covalently modified by the carrier protein, but instead is delivered unchanged to the other side of the membrane. Each type of carrier protein has one or more specific binding sites for its solute (substrate). It transfers the solute across the lipid bilayer by undergoing reversible conformational changes that alternately expose the solute-binding site first on one side of the membrane and then on the other. A schematic model of how such a carrier protein is thought to operate is shown in Figure 11-6. When the carrier is saturated (that is, when all solute-binding sites are occupied), the rate of transport is maximal. This rate, referred to as Vmax, is characteristic of the specific carrier and reflects the rate with which the carrier can flip between its two conformational states. In addition, each transporter protein has a characteristic binding constant for its solute,Km, equal to the concentration of solute when the transport rate is half its maximum value (Figure 11-7). As with enzymes, the binding of solute can be blocked specifically by either competitive inhibitors (which compete for the same binding site and may or may not be transported by the carrier) or noncompetitive...
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...NAVOTAS ADVENTIST ELEMENTARY SCHOOL, INC. 516 Gov. Pascual St., Daanghari, Navotas City First Periodical Test SCIENCE IV Name: _______________________ Date: ______________ Score: _________ Rating: _______ Choose the letter of the best answer and write them on the space before the blanks: ____ 1. The living framework of our body is called ______. a. Circulatory System c. Skeletal System b. Digestive System d. Urinary System ____ 2. How many bones are there in the human adult? a. 270 b. 206 c. 270 d. 275 ____ 3. The smallest bone in the body is called ___. a. femur b. anvil c. stirrup d. hammer ____ 4. A rounded box that encloses the brain is called ___. a. cranium b. skull c. facial bone d. crane ____ 5. The bony part of the head is called ____. a. cranium b. skull c. facial bone d. crane ____ 6. The place where the bones meet together are called ___. a. ligament b. joint c. tendon d. cartilage ____ 7. A white, stingy, tough tissue at the end of each muscle is called ____. a. cranium b. tendons c. facial bone d. crane ____ 8. Which of the following bones protect the heart and lungs? a. ribs b. pelvic bone c. cranium d. mandible ____ 9. What is the shape of the scapula? a. triangular b. circular c. rectangular d. rounded ____ 10. How many bones are there in the axial skeleton? a. 80 b. 70 c. 60 d. 50 ____ 11. How many pairs of ribs do NOT attached to the breastbone? a. 1 b. 2...
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