...PERCEPTIONS OF GENETIC TESTING AMONG HISPANIC FAMILY MEMBERS OF BREAST CANCER SURVIVORS Objective: To provide a preliminary description of the interest, awareness, and perceptions of genetic testing among Hispanics with a family history of breast cancer Design: This cross-sectional pilot study used interpersonal structured interviews for data collection. Participants: We interviewed 48 Hispanics without breast cancer but who had a family member with breast cancer; participants lived in San Antonio and the surrounding area. Main Outcome: The outcomes were interest in breast cancer genetic testing, awareness about genetic testing, perceived risk of carrying a breast cancer susceptibility gene, and the perceived benefits and risks associated with a genetic test. Measures: Items previously used in research regarding interest and perceived genetic risk and a previously validated benefits and riskslimitations scale for genetic testing commonly used by other researchers were used to measure the outcomes. Results: Awareness of genetic testing for breast cancer susceptibility was very low, yet most (82%) participants were interested in a genetic test for breast cancer susceptibility. Participants were more likely to identify with the benefits than the potential risks of genetic testing. The most highly endorsed benefits were to know to take better care of one’s self and to undergo more frequent screening. Conclusions: Hispanics seem to have positive perceptions about genetic testing for...
Words: 4990 - Pages: 20
...was established in, uh, 2003 through an endowment by, uh, Dr. Sydney Brenner, commander of honor and, ah, fellow of the Royal Society, who was the joint winner of the Nobel Prize for Physiology or Medicine in 2002. The lecture is delivered annually in any field of biological sciences, but preference is given to the general areas in which Francis Crick himself worked—uh, genetics, molecular biology, and neurobiology. And you’ll see that this, ah, evening’s speaker is imminently well-suited to talk to us. So, the Francis Crick lecturer, ah, for this year is Dr. Simon Fisher. Dr. Fisher is, ah, a Royal Society, ah, research fellow, um, so he’s, ah, a fellow of one of our flagship, ah, schemes for young scientists in the society, and he’s also reader in molecular and neuroscience in Oxford at the Welcomme Trust Centre for Human Genetics. Ah, he’s head there of the molecular neuroscience group. His laboratory carries out research into molecular mechanisms that underlie human speech and language. Simon is also, ah, the Isobel Laing Fellow at Oriel College in Oxford, where he teaches biochemistry and, ah, genetics to undergraduates, ah, studying medicine. So, lucky undergraduates to be getting it straight from the horse’s mouth. The Francis Crick Lecture was...
Words: 14101 - Pages: 57
...morphologic characteristics and includes nemaline myopathy, central core disease, myotubular (centronuclear) myopathy and congenital fiber type disproportion. In most of these disorders, there are 3 distinct subtypes: severe infantile, benign congenital and adult onset forms. The mode of inheritance and gene loci are variable, although each disorder shares the common clinical features including facial and prominent neck flexor weakness and preferential respiratory muscle involvement. All mutations identified in nemaline myopathy are localized to the actin filament components, suggesting that the disease is related to sarcoplasmic thin filaments or Z-protein abnormalities. On the other hand, X-linked myotubular myopathy has mutations in a family of tyrosine phosphatase (myotubularin gene) and central core disease in ryanodine receptor gene. In all these disorders, the common pathologic features are small muscle fibers with type 1 fiber atrophy and predominance, which account for the small muscle bulk and generalized muscle weakness. INTRODUCTION NEMALINE MYOPATHY The term congenital myopathy is applied to muscle disorders presenting with generalized muscle weakness and hypotonia from early infancy with delayed developmental milestones. Dysmorphic features such as elongated face, scoliosis and contracture of joints are common. The congenital myopathies have been classified into various diseases based on pathologic characteristics, including nemaline myopathy, central...
Words: 2781 - Pages: 12
...The Gay Gene Benjamin C. Bell Jr. Abstract This paper is an expose on one of the prevailing discussions on the gay gene. It has long been debated as to whether or not a person who has embraced has lived gay or lesbian is born that way. The question being is this an act of their own volition or are they born that way. On one side there are those who assert that people are biologically predisposed to such a lifestyle and cannot help but pursue same sex relationships. On the other side there are those who argue it is an issue of will, and one of choice. I believe the current research is inconclusive on both sides. The data is up to date and the results are a testimony to how much ignorance there is about this controversy. As we attempt to understand those whose sexual point of reference we question we must remember that all human beings are the Creator’s offspring and should be treated as such no matter how we feel about their sexual orientation. We must employ respect and reason as we journey down the road to understanding this intriguing subject. People may be different in their sexual expression and it may concern us to no end. The truth of the matter is if their behavior is in our estimation deviant, no matter how wrong we think it is we have a responsibility to treat them in a way that is respectable and proper. People are at liberty to express themselves sexually as they deem it fitting for them. This paper is designed to deliver a biological and scientific perspective...
Words: 10197 - Pages: 41
...interventions aimed at preventing depression in youth. Basic epidemiologic and clinical research indicates that increased risk for depression is associated with being female; a family history of depression, particularly in a parent; subclinical depressive symptoms; anxiety; stressful life events; neurobiological dysregulation; temperament/personality (e.g., neuroticism); negative cognitions; problems in self-regulation and coping; and interpersonal dysfunction. These vulnerabilities both increase individuals’ chances of encountering stress and decrease their ability to deal with the stress once it occurs. Although several existing depression-prevention studies have targeted one or more of these risk factors, the efficacy of these various prevention programs for youth with different combinations of these risk factors needs to be investigated further. Most existing depression-prevention programs in youth have used cognitive– behavioral techniques, with some success. Other depressionprevention strategies have included training in coping, social problem solving, social skills, communication skills, and parenting. A comprehensive prevention program is recommended that includes multiple intervention components, each of which addresses risk and protective factors across different domains and levels of analysis. (Am J Prev Med 2006;31(6S1):S104 –S125) © 2006...
Words: 18951 - Pages: 76
...Employment News 31 May - 6 June 2014 www.employmentnews.gov.in 21 UNION PUBLIC SERVICE COMMISSION EXAMINATION NOTICE NO. 09/2014-CSP (LAST DATE FOR RECEIPT OF APPLICATIONS : 30/06/2014) DATE :31.05.2014 CIVIL SERVICES EXAMINATION, 2014 (Commission’s website-http://upsc.gov.in) F. No. 1/5/2013-E.I(B) : Preliminary Examination of the Civil Services Examination for recruitment to the Services and Posts mentioned below will be held by the Union Public Service Commission on 24th Aug., 2014 in accordance with the Rules published by the Department of Personnel & Training in the Gazette of India Extraordinary dated 31st May, 2014. (i) Indian Administrative Service. (ii) Indian Foreign Service. (iii) Indian Police Service. (iv) Indian P & T Accounts & Finance Service, Group ‘A’. (v) Indian Audit and Accounts Service, Group ‘A’. (vi) Indian Revenue Service (Customs and Central Excise), Group ‘A’. (vii) Indian Defence Accounts Service, Group ‘A’. (viii) Indian Revenue Service (I.T.), Group ‘A’. (ix) Indian Ordnance Factories Service, Group ‘A’ (Assistant Works Manager, Administration). (x) Indian Postal Service, Group ‘A’. (xi) Indian Civil Accounts Service, Group ‘A’. (xii) Indian Railway Traffic Service, Group ‘A’. (xiii) Indian Railway Accounts Service, Group 'A'. (xiv) Indian Railway Personnel Service, Group ‘A’. (xv) Post of Assistant Security Commissioner in Railway Protection Force, Group ‘A’ (xvi) Indian Defence Estates Service, Group...
Words: 47693 - Pages: 191
...Employment News 11 - 17 February 2012 www.employmentnews.gov.in 21 Union Public Service Commission EXAMINATION NOTICE NO. 04/2012-CSP DATED 11.02.2012 (LAST DATE FOR RECEIPT OF APPLICATIONS : 05.03.2012) CIVIL SERVICES EXAMINATION, 2012 (Commission's website - http://www.upsc.gov.in) F. No. 1/4/2011-E.I(B) : Preliminary Examination of the Civil Services Examination for recruitment to the Services and Posts mentioned below will be held by the Union Public Service Commission on 20th May, 2012 in accordance with the Rules published by the Department of Personnel & Training in the Gazette of India Extraordinary dated 4th February, 2012. (i) Indian Administrative Service. (ii) Indian Foreign Service. (iii) Indian Police Service. (iv) Indian P & T Accounts & Finance Service, Group ‘A’. (v) Indian Audit and Accounts Service, Group ‘A’. (vi) Indian Revenue Service (Customs and Central Excise), Group ‘A’. (vii) Indian Defence Accounts Service, Group ‘A’. (viii) Indian Revenue Service (I.T.), Group ‘A’. (ix) Indian Ordnance Factories Service, Group ‘A’ (Assistant Works Manager, Administration). (x) Indian Postal Service, Group ‘A’. (xi) Indian Civil Accounts Service, Group ‘A’. (xii) Indian Railway Traffic Service, Group ‘A’. (xiii) Indian Railway Accounts Service, Group 'A'. (xiv) Indian Railway Personnel Service, Group ‘A’. (xv) Post of Assistant Security Commissioner in Railway Protection Force, Group ‘A’ (xvi) Indian Defence Estates Service, Group ‘A’. (xvii) Indian Information...
Words: 50586 - Pages: 203
...antarabangsa dari segi gaya dan format. Perkataan “tesis” dalam panduan ini dimaksudkan sebagai hasil penulisan ilmiah bagi pelajar program pengajian siswazah diperingkat Sarjana dan Doktor Falsafah secara penyelidikan. Perbincangan dalam panduan ini keseluruhannya juga menggunakan perkataan “tesis” bagi maksud penulisan ilmiah untuk Projek Sarjana Muda (PSM), Laporan Projek Sarjana dan Disertasi Penyelidikan bagi pengajian secara mod campuran. Walau bagaimanapun, panduan ini tidak bermaksud untuk menyediakan semua gaya format bagi semua bentuk rujukan. Sekiranya gaya format khusus yang diperlukan tidak ada di dalam panduan ini, pelajar boleh merujuk kepada panduan penulisan ilmiah lain seperti “American Psychological Association Manual” edisi ke-6. Pusat Pengajian Siswazah Universiti Tun Hussein Onn Malaysia Mac 2011 ii PENGHARGAAN Pusat Pengajian Siswazah, Universiti Tun Hussein Onn Malaysia (UTHM) mengucapkan setinggi-tinggi terima kasih kepada staf yang telah menyumbangkan tenaga dan idea dalam...
Words: 10578 - Pages: 43
...Arch Iran Med 2010; 13 (2): 143 – 146 Mini Review Five Common Cancers in Iran Shadi Kolahdoozan MD MPH*, Alireza Sadjadi MD MPH**, Amir Reza Radmard MD***, • Hooman Khademi MD MPH * Iran as a developing nation is in epidemiological transition from communicable to noncommunicable diseases. Although, cancer is the third cause of death in Iran, it`s mortality are on the rise during recent decades. This mini-review was carried out to provide a general viewpoint on common cancers incidence in Iran and to explain incidental differences that may help us to establish early detection programs and investigate population risk factors. A detailed PubMed, Scopus and Google scholar search were made from 2000 to 2009. The basic inclusion criteria were all relevant studies focused on cancer epidemiological data from Iran. Overall age-standard incidence rate per 100 000 population according to primary site is 110.43 in males and 98.23 in females. The five most common cancers (except skin cancer) are stomach, esophagus, colon-rectum, bladder and leukemia in males, and in females are breast, esophagus, stomach, colon-rectum and cervix uteri. The incidence rates of gastrointestinal cancers are high in Iran (it is one of the known areas with a high incidence of GI cancers). Breast cancer mainly affects Iranian women about a decade earlier than Western countries and younger cases are affected by an increasing rate of colorectal cancer in Iran, near the Western rates. Archives of Iranian Medicine...
Words: 3196 - Pages: 13
...The impact of health and health behaviours on educational outcomes in high-income countries: a review of the evidence Marc Suhrcke, School of Medicine, Health Policy and Practice, University of East Anglia, United Kingdom Carmen de Paz Nieves, Fundación Ideas, Madrid, Spain ISBN 978 92 890 0220 2 Keywords HEALTH BEHAVIOR - HEALTH STATUS - EDUCATIONAL STATUS - RISK FACTORS - SOCIOECONOMIC FACTORS - REVIEW LITERATURE Suggested citation Suhrcke M, de Paz Nieves C (2011). The impact of health and health behaviours on educational outcomes in highincome countries: a review of the evidence. Copenhagen, WHO Regional Office for Europe. Address requests about publications of the WHO Regional Office for Europe to: Publications WHO Regional Office for Europe Scherfigsvej 8 DK-2100 Copenhagen Ø, Denmark Alternatively, complete an online request form for documentation, health information, or for permission to quote or translate, on the Regional Office web site (http://www.euro.who.int/pubrequest). © World Health Organization 2011 All rights reserved. The Regional Office for Europe of the World Health Organization welcomes requests for permission to reproduce or translate its publications, in part or in full. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning...
Words: 18944 - Pages: 76
...It abhors beautification. Set to patiently study the story of destitute. It uncovers the Humiliated Reality. It is the historian of the present time. It is real, alive and bloodthirsty. It deals with the lower classes. It is documented. It is close to spoken language. It deals with presenting accurate and detailed account of the story. It prioritizes the analysis of personal spirit to society. It puts forward the anti-morals. Writers such as Freud see the love, regret and fear emerging from human’s unsatisfied physical and sexual...
Words: 6631 - Pages: 27
...accessibility of healthful foods), which can influence health-related behaviors. Evidence has accumulated, however, pointing to socioeconomic factors such as income, wealth, and education as the fundamental causes of a wide range of health outcomes. This article broadly reviews some of the knowledge accumulated to date that highlights the importance of social—and particularly socioeconomic— factors in shaping health, and plausible pathways and biological mechanisms that may explain their effects. We also discuss challenges to advancing this knowledge and how they might be overcome. University of California, San Francisco, School of Medicine, Department of Family and Community Medicine, Center on Social Disparities in Health, San Francisco, CA a University of California, San Francisco, School of Medicine, Department of Family and Community Medicine, Center for Health and Community, San...
Words: 9260 - Pages: 38
...robinson@earthopensource.org June 2012 Disclaimer The views and opinions expressed in this paper, or otherwise published by EOS, are those of the authors and do not represent the official policy, position, or views of other organizations, universities, companies, or corporations that the authors may be affiliated with. GMO Myths and Truths 2 About the authors Michael Antoniou, PhD is reader in molecular genetics and head, Gene Expression and Therapy Group, King’s Cols: lege London School of Medicine, London, UK. He has 28 years’ experience in the use of genetic engineering technology investigating gene organisation and control, with over 40 peer reviewed publications of original work, and holds inventor status on a number of gene expression biotechnology patents. Dr Antoniou has a large network of collaborators in industry and academia who are making use of his discoveries in gene control mechanisms for the production of research, diagnostic and therapeutic products and safe and efficacious human somatic gene therapy for inherited and acquired genetic disorders. Claire Robinson, MPhil, is research director at Earth Open Source. She has a background in investigative reporting and the communication of topics relating to public health, science and policy, and the environment. She is an editor at GMWatch (www.gmwatch.org), a public information service...
Words: 78055 - Pages: 313
...3 Global challenges, need for R&I and economic dimensions of Digital Technology AUTUMN 2013 Copyright © ARTEMIS Industry Association & ITEA Office Association Permission to reproduce any text from this publication for non-commercial purposes is granted, provided that the source is credited. First edition, autumn 2013 www.artemis-ia.eu & www.itea2.org ISBN: 978-90-817213-2-5 5 Preamble This updated document1 is the joint result of the industry represented in the ARTEMIS Industry Association and ITEA and expresses the common industry ambition. Its creation was initiated by the ARTEMIS ITEA Cooperation Committee (AICC). The main goal of this update of the ITEA-ARTEMIS high-level vision 2030, version 2012 is to add a quantitative description of the impact of software innovation on revenues and labour. There are also other aspects of the impact of software innovation, like eco-systems, community building and standardisation. However these are not the focus of this year’s update. Disclaimer The trends and predictions presented in this document are based on publicly available sources. We rely on these sources, without independent verification of the information presented. The nature of this document is for a large part rather a compilation of existing material, than a reinvention of insights. The statements made by Roland Berger Strategy Consultants are based on assumptions held to be accurate on the basis of the information available. However, Roland Berger Strategy...
Words: 19271 - Pages: 78
...causes of neonatal and postneonatal death (1–3). LBW and preterm birth are also associated with infant and childhood morbidity, including asthma (4) and neurodevelopmental delays (3,5). Recent evidence suggests that preterm birth and LBW are also linked to adverse health in adulthood (6), including insulin resistance (7), hypertension (8) and coronary heart disease (9). The potentially serious health consequences of these birth outcomes underscore the public health importance of preventing LBW and preterm birth by identifying and correcting modifiable risk factors. ● head circumference Maternal nutritional status is important to maternal and fetal well-being. BMI, weight (kg)/height squared (m2), is influenced by ethnicity and genetics but may also serve as a measure of adiposity and energy balance (10 –12). Although much recent research in...
Words: 6181 - Pages: 25
