Both protagonists experience isolation and alienation which leads to fatal results in Sinclair Ross’ “The Painted Door” and “One’s A Heifer”. Ann’s constant lonely state caused by her husband John always being busy at work and not being there for her, also her not going out and having fun which she always dreams to do. As well as the setting creating a sense of isolation for her, only intensifying her own inner loneliness. These result in Ann being unsatisfied with John and leading to the adultery with Steven, Her sudden realization that John was the man she loved and John's death. Vickers sense of isolation is amplified by his cabin being as dirty as it is, pushing away his only chance of a girlfriend and communication and playing checker