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Unit 1. Case Study 1. Tell Me About Blood

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Unit 1. Case Study 1. Tell Me About Blood 1. What is the significance of a lower-than-normal hematocrit? What is the effect of a bacterial infection on the hematocrit? (PAGE 618 619)
First, hematocrit (HCT) is the percentage of blood made up of red blood cells. Usually measured by centrifuging a blood sample in a graduated tube and then reading the volume of red blood cells and dividing it by the total volume of blood in a sample. A significant drop in hematocrit is an indication of anemia (lower-than-normal number of red blood cells (Jenkins & Tortora, 2013). A bacterial infection would increase the production of white blood cells to fight off the infection. The hematocrit would have a thicker buffer layer (white blood cells) causing the red blood cell production to slightly decrease which would decrease the ratio of red blood cells to whole blood volume. 2. Compare the development of lymphocytes with the development of the other formed elements. (PAGES 629 631 632 769)
Lymphocytes and the other formed elements are developed from pluripotent stem cells. The pluripotent stem cells generate myeloid stem cells and lymphoid stem cells. Myeloid stem cells start and complete their development in red bone marrow and give rise to red blood cells, platelets, eosinophils, basophils, neutrophils, and monocytes. Lymphoid stem cells begin development in the red bone marrow, but some are completed in the lymphatic tissues, where they give rise to lymphocytes. The B cell lymphocytes begin and finished in the red bone marrow and the T cell lymphocytes begin in the red bone marrow, but they mature in the thymus (Jenkins & Tortora, 2013).

3. What is erythropoiesis? Which factors speed up and slow down erythropoiesis? (PAGES 624-625)
Erythropoiesis is the specific production of red blood cells or erythrocytes. It starts in the red bone marrow with a

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