Premium Essay

Useful Medicinal Compounds Derived from Animals

In:

Submitted By junnting
Words 643
Pages 3
Tittle: Useful medicinal compounds derived from animals In modern medication, monoclonal antibody has been used to treat various kinds of disease. For cancer therapy, monoclonal antibody is extremely success. Monoclonal antibody, an immune protein with specific binding site and purified from mouse, can bind with target protein (Campbell NA, 1996). Such as: Specific antigen, growth factor and so on. As tumor cell always avoid immune system and even try to suppress the immune response, they always avoid immune defense. However, if monoclonal antibody is presented, they will bind with the target protein and immune system can recognize. Finally, immune response will be triggered. Tumor cell can be killed by B-cell or Phagocyte. Over a hundred years ago, target drug idea has been proposed. If a drug can be delivery to the target site precisely, the adverse effect of the drug can be minimized. “Delivery the drug to the target site” became a challenge the scientist. In the 1970s, B-cell has been discovered and played essential role (Biotech Resources, 1995-7). Anyways, as the technology, antibody cannot be cloned directly. For this reason, mouse antibody is used. In the beginning, some antigen was injected into the mouse and induced B-cell proliferation. Then, purified the antibody from the mouse. Compare with traditional drug, monoclonal antibody has a relatively low adverse effect. However, as murine monoclonal antibody is not a human protein. It only has a short half- life and causes an allergy response (Biotech Resources, 1989). Nowadays, chimeric and full human monoclonal antibodies has been introduced but have not yet fully developed.

Part 2
 When the organism live in the world, they always compete with other organism especially the same species. For the large mammals, they also threaten by the surrounding substance. e.g. Microorganism,poison and

Similar Documents

Free Essay

Tawa-Tawa

...Euphorbia Hirta or "tawa-tawa" Tawa Tawa or  Gatas Gatas  (Euphorbia Hirt)        The Mindoro Post, within its article entitled "Dengue Fever Cure using Tawa tawa" (released The month of January 2010, utilized July 2010), creates, "many individuals understand and also have attested in order to the truth that these people and many more happen to be healed associated with dengue using a simple grass. This particular grass is known as Gatas Gatas within the land associated with Leyte. However in Butuan  and Cagayan de Oro  these people call this “Tawa Tawa” ·               At the same time, a wesite  upon Filipino therapeutic grass offers the organic category associated with Tawa Tawa grass  as well as explains which, "its blossoms tend to be several, each about 5  to 8 cm across. Sepals as well as petals tend to be obovate-oblong, yellowish-green, as well as protected along with big, reddish-brown smears” The effectiveness of Tawa Tawa Plant    ·              One of the studies proving Tawa Tawa's efficacy is an investigatory project entitled "The Effectivity of Euphorbia hirta L. (Tawa-tawa), Prepared in Teabag Form, on Increasing Platelet Levels in Mus musculus (White Mice)." The said science project won the Student Research Presentation sponsored by the College of Agriculture atXavier University - Ateneo de Cagayan in thePhilippines. ·            The said project, as the title suggests, probes on increasing blood platelet levels using Tawa Tawa plant. For the...

Words: 8092 - Pages: 33

Premium Essay

Summary: The Dangers Of Legalizing Medical Marijuana

...topic of marijuana as a medical drug for treatment has sparked much controversy. Generally people tend to be fiercely on one side, for or against medicinal marijuana, while many remain undecided, believing much more research is needed. Recent studies on medicinal marijuana show benefits in its use for cancer, seizures, and post-traumatic stress disorder but conflicting reports cause doubt in its benefits. Some studies have found that both compounds found in marijuana tetrahydrocannabinol (THC), which is a psychoactive chemical and cannabidiol (CBD) which is a non-psychoactive chemical found in the marijuana plant, to have cancer fight properties. Cancer research has shown that marijuana can drastically reduce nausea associated with chemotherapy...

Words: 1379 - Pages: 6

Free Essay

Ethnopharmacological Approach in Medicine Discovery

...history and is one of the great living traditions. Considerable research on pharmacognosy, chemistry, pharmacology and clinical therapeutics has been carried out on Ayurvedic medicinal plants. Several preclinical and clinical studies have examined cytoprotective, immunomodulatory and immunoadjuvant potential of Ayurvedic medicines. The ethnopharmacology knowledge, is holistic and systems approach supported by experiential base can serve as an innovative and powerful discovery engine for newer, safer and affordable medicines. The Process of Modern Drug Discovery using Ethnopharmacology The first stage should be the reported use of a natural occurring material for some purpose which can be related to a medicinal use. There must be an indication of a genuine effect and therefore, the material needs to be identified and characterized. It can be collected for test studies which comprises tests for relevant biological activity linked with isolation and structure determination of any chemical present that might be responsible. The active compounds are discovered by fractionation of the extract linked with testing for activity of each fraction until pure compounds are isolation. This is Bioassay-guided Fractionation. When the activities are proven, these compounds serve as leads to development of clinically useful products. Information collection In-depth studies carried out by field workers in a particular community of a particular ethnic group on the use of plants and their material...

Words: 1926 - Pages: 8

Free Essay

Natural Products

...Natural product From Wikipedia, the free encyclopedia Jump to: navigation, search | This article needs additional citations for verification. Please help improve this article by adding reliable references. Unsourced material may be challenged and removed. (January 2009) | Paclitaxel (Taxol) is a natural product derived from the Yew tree.[1] A natural product is a chemical compound or substance produced by a living organism - found in nature that usually has a pharmacological or biological activity for use in pharmaceutical drug discovery and drug design. A natural product can be considered as such even if it can be prepared by total synthesis. These small molecules provide the source or inspiration for the majority of FDA-approved agents and continue to be one of the major sources of inspiration for drug discovery. In particular, these compounds are important in the treatment of life-threatening conditions.[2] Contents[hide] * 1 Natural sources * 2 Screening of natural products * 2.1 The plant kingdom * 2.2 The microbial world * 2.3 The marine world * 2.4 Animal sources * 2.5 Venoms and toxins * 3 Traditional Medicine * 4 Isolation and purification * 5 Synthesis * 6 See also * 7 References * 8 External links * 9 Further reading | [edit] Natural sources Natural products may be extracted from tissues of terrestrial plants, marine organisms or microorganism fermentation broths. A crude (untreated) extract from any one of these...

Words: 3118 - Pages: 13

Premium Essay

Hsc/440 Week 1

...LITERATURE REVIEW FOR ALTERNATIVE AND HOLISTIC MEDICINE Summer Olson University of South Dakota September 5, 2014 Author Note Summer Olson, Department of Health Sciences, University of South Dakota Summer Olson is now a junior at the University of South Dakota. This paper fulfills the critical writing graduate component of the course HSC 440, Major Issues in Health and Human Services. Correspondence concerning this paper should be addressed to Summer Olson, Summer.Olson@coyotes.usd.edu   Article # 1 A study by Arvind Chopra (2013) examined how an Ayurvedic medicinal technique compares to modern remedies for osteoarthritis. Dr. Chopra is an associate at the Center for Rheumatic disease where he is a leader in research. The study...

Words: 3635 - Pages: 15

Premium Essay

Which of the Different Solutions of Ectyonin Extract from Microciona Prolifera Is the Most Effective in Inhibiting the Growth of the Bacteria.

...breached. Researchers around the globe developed antibiotics, such as penicillin and glycopeptides that could kill or slow down the growth of S. aureus bacteria. By 1950, it was reported that 40% of the hospital S. aureus isolates were penicillin and glycopeptide resistant; and recently, this has risen to 80%. Microciona prolifera, or red sponge, contains substances with antibiotic capacity that could kill or slow down the growth of a strain of S. aureus bacteria suggesting possibilities for creating novel drugs to treat the infectious skin disease. This study aims to determine the most efficient antibiotic solution of ectyonin extract from Microciona prolifera against Staphylococcus aureus bacteria. Statement of the Problem General Problem This study aims to compare which of the different solutions of Ectyonin extract from Microciona prolifera is the most effective in inhibiting the growth of the bacteria. Specific Problem Specifically it aims to answer the following questions: 1. Which of the four solutions is most effective in inhibiting the growth of Staphylococcus aureus bacteria? 2. Does water affect the solution against the bacteria? 3. Did the colony count of the bacteria increase after putting the different solutions? Hypotheses 1. The solution with the smallest amount of ectyonin is most effective in inhibiting the growth of Staphylococcus aureus bacteria....

Words: 3591 - Pages: 15

Premium Essay

The Effect of Alstonia Bonnie on the Haematology Parameters of Male Rats

...CHAPTER ONE INTRODUCTION AND LITERATURE REVIEW 1.1 INTRODUCTION Many cultures throughout the world still rely on indigenous medicinal plants for their primary health care needs (Farnsworth et al., 1985). To date, 25% of modern medicines are derived from plants that have been used by traditional medical practitioners (Cragg and Newman, 2005). It is a fact that traditional systems of medicine have become a topic of global importance. African countries are at a stage where traditional medicine is considered more for its capacity to generate other medicine than for its own sake. In many cases research undertakings and the commercial use stemming from that research have always relied on information provided by the local communities and, in many instances, have hardly benefited from the research results (Rukangira, 2004) . In Africa, traditional healers and remedies made from plants play an important role in the health of millions of people. (Rukangira, 2004). Typically, studies on the medicinal plants such as Alstonia boonei have focused on the bioactivity of its chemical constituents, ethnobotany, pharmacology, and taxonomy. However, a comprehensive or systematic review on the plant is lacking. Furthermore, in much of the older literature concerning West Africa, the name Alstonia congensis has been erroneously used for Alstonia boonei. Consequently, this paper examined the effect of aqueous bark extracts of Alstonia boonei on the haematological parameters of male wistar abino...

Words: 5961 - Pages: 24

Premium Essay

Malunggay

...Accepted: November 20, 2005; Published: December 1, 2005 Copyright: ©2005 Jed W. Fahey This is an Open Access article distributed under the terms of the C reative C ommons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Moringa appears to be a nutritional and medicinal cornucopia. The author, a Western-trained nutritional biochemist who has studied some of Moringa’s phytochemicals for almost a decade, gives a brief commentary and extensive references, and presents a table introducing some of the tree’s most intriguing features. This is the first article in a series, and will be followed by more detailed analysis of some of the strongest claims made regarding this edible plant. Vie Art Abstract Moringa oleifera, or the horseradish tree, is a pan-tropical species that is known by such regional names as benzolive, drumstick tree, kelor, marango, mlonge, mulangay, nébéday, saijhan, and sajna. Over the past two decades, many reports have appeared in mainstream scientific journals describing its nutritional and medicinal properties. Its utility as a non-food product has also been extensively described, but will not be discussed herein, (e.g. lumber,...

Words: 10491 - Pages: 42

Free Essay

Comparative Ultrastructural Analyses of Platelets and fibrin Networks Using the Murine Model of Asthma

...ARTICLE IN PRESS Experimental and Toxicologic Pathology 59 (2007) 105–114 www.elsevier.de/etp Comparative ultrastructural analyses of platelets and fibrin networks using the murine model of asthma E. PretoriusÃ, O.E. Ekpo, E. Smit Department of Anatomy, School of Health Sciences, Faculty of Health Sciences, University of Pretoria, BMW Building, P.O. Box 2034, Pretoria 0001, South Africa Received 10 October 2006; accepted 13 February 2007 Abstract The murine Balb/c asthma model has been used successfully for a number of in vivo immunological applications and for testing novel therapeutics, and it is a reliable, clinically relevant facsimile of the human disease. Here we investigate whether this model can be used to study other components of the human body, e.g. ultrastrucure. In particular, we investigate the effect of the phytomedicine Euphorbia hirta (used to treat asthma), on the ultrastructure of fibrin as well as platelets, cellular structures that both play an important role in the coagulation process. Hydrocortisone is used as positive control. Ultrastructure of the fibrin networks and platelets of control mice were compared to mice that were asthmatic, treated with two concentrations of hydrocortisone and one concentration of the plant material. Results indicate control mice possess major, thick fibers and minor thin fibers as well as tight round platelet aggregates with typical pseudopodia formation. Minor fibers of asthmatic mice have a netlike appearance covering...

Words: 5920 - Pages: 24

Free Essay

“Anti-Fungal of Marigold (Calendula Officinalis) Flower Extract

...“Anti-fungal of Marigold (Calendula officinalis) flower extract” I. INTRODUCTION Background of the Study From hundreds of centuries ago, in ancient times, and from times when the human being was active as today on the scene of life and fighting for life, along with his struggles to provide food and clothing, he was thinking about his health, finding ways to live healthy and relieving physical ailments and illness which was later called the medicine and of course the herbal medicine which is now applicable for us. Flowers always make people better, happier, and more helpful; they are sunshine, food and medicine for the soul. A popular garden plant, Marigold has been valued for many centuries for its' exceptional healing powers and is particularly remarkable in the treatment of wounds. When used for medicinal purposes, it is commonly referred to as 'Calendula'. (Sunset Western Garden Book) The “marigold” (Calendula officinalis) also called “ruddles”, common marigold, garden marigold, English marigold, or Scottish marigold is a plant in the genus Calendula of the family Asteraceae. It is probably native to southern Europe, though its long history of cultivation makes its precise origin unknown, and it may possibly be of garden origin. It is also widely naturalized further north in Europe (north to southern England) and elsewhere in warm temperate regions of the world. “Marigold” is well known as a wound-healing, antiseptic and stimulating remedy, but in fact modern herbalists...

Words: 7818 - Pages: 32

Premium Essay

Gumamela Petals as Dishwashing Liquid

...removes all the dirt of common kitchen tools. Imagine yourself washing the dishes without using any dishwashing liquid, how will you easily remove those stains and grease? This study shows how a simple organic material that can be easily found elsewhere can be turned into something as useful as dishwashing liquid. Background of the Study This research aims to produce a dishwashing liquid out of Gumamela petals that will remove the stains and grease in common kitchen tools. This study will make use of Gumamela petals which contains mucilage that effectively removes stains or grease present in common kitchen tools. Significance of the Study The study will produce a new kind of dishwashing liquid that is completely organic. It will make use of Gumamela petals mixed with water and calamansi extract to produce a dishwashing liquid that is chemical free yet effective in removing stain or grease present in common kitchen tools at the most affordable price compare to the commercial brand sold in the market. The dishwashing liquid will be making use of gumamela petals which are being ignored if not use as ornamentals. So, this will help people not to waste the gumamela petals and make it more useful and...

Words: 2064 - Pages: 9

Free Essay

Insect Repelant

...insects, example, the mosquito is responsible for spreading malaria, as well as ticks which spread Lyme disease. The citizens of first world countries typically tend to become infected through the bite or sting of insects and bugs while they are abroad. Indeed, travelers to exotic locales are often affected by nasty diseases transmitted by insects or bugs and bring such disease home with them. The greatest dangers lurk closer home and one need not travel across the world to face tiny pests. Many local insects and bugs in North America can cause serious diseases. Therefore, protecting the entire family through the prudent use of good quality insect and bug repellents is a necessity. Insects and bugs as vectors Each year, millions of people die from diseases transmitted by insects and other pests acting as vectors - an organism that acts as a host or carrier of some minute pathogenic organism that it transfers or transmits to a human host. In the case of malaria, for example, the mosquito is a vector, while malaria is actually caused by the protozoan parasite plasmodium. The human being is the final host. Not all diseases passed on by...

Words: 11126 - Pages: 45

Free Essay

Biotechnology

...Biotechnology Insulin crystals Biotechnology is the use of living systems and organisms to develop or make useful products, or "any technological application that uses biological systems, living organisms or derivatives thereof, to make or modify products or processes for specific use" (UN Convention on Biological Diversity).[1] Depending on the tools and applications, it often overlaps with the (related) fields of bioengineering and biomedical engineering. For thousands of years, humankind has used biotechnology in agriculture, food production and medicine.[2] The term itself is largely believed to have been coined in 1919 by Hungarian engineer Karl Ereky. In the late 20th and early 21st century, biotechnology has expanded to include new and diverse sciences such as genomics, recombinant gene technologies, applied immunology, and development of pharmaceutical therapies and diagnostic tests.[3] Definitions of biotechnology The concept of 'biotech' or 'biotechnology' encompasses a wide range of procedures (and history) for modifying living organisms according to human purposes — going back to domestication of animals, cultivation of plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. Biotechnology is defined by the American Chemical Society as the application of biological organisms, systems, or processes by various...

Words: 6516 - Pages: 27

Premium Essay

Term Paper

...INTRODUCTION                           Soil is the thin layer of organic and inorganic materials that covers the Earth's rocky surface. The organic portion, which is derived from the decayed remains of plants and animals, is concentrated in the dark uppermost topsoil. The inorganic portion made up of rock fragments, was formed over thousands of years by physical and chemical weathering of bedrock. Productive soils are necessary for agriculture to supply the world with sufficient food.                         A soil pollutant is any factor which deteriorates the quality, texture and mineral content of the soil or which disturbs the biological balance of the organisms in the soil. Pollution in soil has adverse effect on plant growth.                 The introduction of substances, biological organisms, or energy into the soil, resulting in a change of the soil quality, which is likely to affect the normal use of the soil or endangering public health and the living environment. Soil contaminants are spilled onto the surface through many different activities. Most of these are the result of accidents involving the vehicles that are transporting waste material from site of origin to a disposal site.                         Soil pollution is particularly dangerous for the environment and our health because soil, either in the mountains or in the plains, contains the largest part of the water we drink and produces all the food we need. There are many types of soil pollution...

Words: 5806 - Pages: 24

Premium Essay

Thesis: Malunggay Cupcake as Supplementary Food

...Acknowledgement We would never have been able to finish our dissertation without the guidance of our neighbors, help from friends, and support from my family. We would like to express my deepest gratitude to my advisor, Mrs. Modie Flores, for her excellent guidance, caring, patience, and providing us with an excellent atmosphere for doing research. We would like to thank our Parents, who let us experience the research of Malunggay Cupcake in the field and practical issues beyond the textbooks, internet, patiently corrected our writing and financially supported our research. We would also like to thank Menchie Hermones, and Ludy Balagosa, for guiding our research for the past several weeks and helping us to develop our background in biochemistry. We would like to thank our Classmates, who as a good friend, was always willing to help and give their best suggestions. It would have been a lonely lab without them. We would also like to thank our parents, two elder sisters, and elder brother. They were always supporting us and encouraging us with their best wishes. We give thanks to God almighty for giving us the understanding, knowledge and wisdom during the course of our study. Finally, we would like to thank our classmate Auntie, Sally Barral. She was always there cheering us up and stood by us through the good times and bad. Dedication ...

Words: 8495 - Pages: 34