...Prader Willi Syndrome “Prader-Willi syndrome is a rare disorder present at birth that results in a number of physical, mental and behavioral problems. A key feature of Prader-Willi (prah-dur VIL-ee) syndrome is a constant sense of hunger that usually begins after the first year of life. People with Prader-Willi syndrome want to eat constantly and usually have trouble controlling their weight. Many complications of Prader-Willi syndrome are due to obesity. If your child has Prader-Willi syndrome, a team of specialists can work with you to manage your child's symptoms and reduce the risk of developing complications.” (Mayo Clinic Staff, 01 May 2013, page 1). “Prader-Willi syndrome is caused by a gene missing on part of chromosome 15. Normally, your parents each pass down a copy of this chromosome. Most patients with Prader-Willi syndrome are missing the genetic material on part of the father's chromosome. The rest of patients with this condition often have two copies of the mother's chromosome 15. The genetic changes occur randomly. Patients usually do not have a family history of the condition.” (Cooke DW, Divall SA, Radovick S, 07 May 2012, para. 2) “Metabolism is a term that is used to describe all chemical reactions involved in maintaining the living state of the cells and the organism. Metabolism can be conveniently divided into two categories: * Catabolism - the breakdown of molecules to obtain energy * Anabolism - the synthesis of all compounds needed by the...
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...note. The young protagonist, Willi, witnesses his mother's act of infidelity and subsequently both desires and betrays her, inexorably bringing about his family's doom. I was the agency of [my father's] downfall. Ancestry and myth, culture, history, and time were ironically composed in the shape of his own boy" (33). "Willi" is a fiction of memory, but memory that has been filtered, and that is still being filtered through a narrator - now child, now adult - presenting an impression of immediacy yet of subtly detached understanding. "We posit an empirical world, yet how can I be here at this desk in this room-and not be here? ... memory is in the ontological sense another reality" (29). This fluid point of view fuses adult-observer and youth participant into one narrative voice, making it possible for Doctorow to avoid both the limits of language and the limited perspective of youth and thus encompass all three visions. Thirteen-year-old Willi has lived the most sheltered of existences: aside from his famiily and a tutor who lives on the premises, he is totally "alone, isolated on our estate ..." (32). Doctorow focuses precisely on the absence of any contact with other children. In his rural isolation Willi "has no friends": he is "not allowed to play with the village children, or to go to their crude schools" (32). Nor is he "permitted to play with the children of the peasants" who work on his parents' estate. In such limiting circumstances, Willi has made a "trinity of Mother...
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...SPED 510 Prader-Willi Syndrome Tonya M. Exum Governor’s State University March 23, 2010 Prader-Willi Syndrome Introduction Prader-Willi Ѕyndrome iѕ a genetic diѕorder. Itѕ featureѕ include food obѕeѕѕion, ѕhortneѕѕ of ѕtature and poor muѕcle tone. It affectѕ boyѕ and girlѕ, and occurѕ in familieѕ from all backgroundѕ. Reѕearch indicateѕ that PWЅ may reѕult becauѕe of four different genetic abnormalitieѕ on chromoѕome 15. In approximately two thirdѕ of caѕeѕ the diѕorder happenѕ becauѕe of a bit miѕѕing affecting chromoѕome 15 coming from the father. In about 30% of caѕeѕ both copieѕ of the chromoѕome are inherited from the mother, inѕtead of one from her and one from the father. A child iѕ born with the condition and currently there iѕ no cure apart from good management. In the vaѕt majority of caѕeѕ, there iѕ only a very ѕmall chance of reoccurrence within a family. (Udwin et.al 2002) Diѕcuѕѕion Many people with PWЅ have typical phyѕical characteriѕticѕ (although there are exceptionѕ) fairer hair and eye colouringѕ than otherѕ in the family, ѕmall handѕ feet (more obviouѕ in older children), almond ѕhaped eyeѕ. Theѕe typical featureѕ are more likely to occur in thoѕe who have a deletion in chromoѕome 15. In thoѕe who are obeѕe, fat iѕ uѕually diѕtributed around the ѕtomach and trunk. Children who have received growth hormone treatment are more likely to be taller and have larger handѕ and feet. Ѕome children will have other phyѕical diѕabilitieѕ...
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...October 31, 2012 Willis and Wanda Notimeleft Estate Plan In reviewing the situation we know that the Notimelefts have a net estate of $8,500,000 and three children. The goals are: to cover their own needs; pass funds on to three children equally; avoid taxes; protect their funds; keep their business private; and give no money to charities. The issues here are: will the Priest be allowed to have an inheritance or would it be given to the church (which looks like a charity to Willis and Wanda); would Darlene’s manipulating husband spend the money and what would happen in the case of divorce; what about possible grandchildren (does Ohno have a sibling?); and when Derelict is in prison would his inheritance be required to pay restitution? What happens if Willis or Wanda are incapacitated? The first thing I would advise would be to open a Revocable Living Trust for Willis (Trust A), one for Wanda (Trust B), and a Children’s trust with a spend-thrift clause to keep Derelict from spending his inheritance foolishly. Trust funds up to $5,120,000 are excluded from estate taxes so I would fund Wanda’s trust to that amount, and fund Willis’ trust with the rest. This would give them lower estate taxes because they would not be paying on the total amount. These trusts will avoid probate when the time comes which is a concern of Wanda and Willis. I would list the children’s trust as the beneficiary to Willis’ and Wanda’s trusts upon their deaths. Wanda and Willis are still alive...
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...characteristics resemble those found in the myths we are studying. We would like to hear your thoughts on whether the stunt in question could be pulled off in real-life. In a scene from Die Hard, the main character, played by Bruce Willis, survives an explosion on the rooftop of a skyscraper by tying a fire hose to his waist, which breaks his fall, and allows him to smash a window of a lower story and take cover within the that story of the building. Willis falls 2-3 floors before the hose brings him to a complete stop. Now, as much as we love to witness the unlikely on a movie screen, we find it highly improbable that this could happen for a multitude of reasons. An average fire hose is about two and a half inches in diameter, anywhere from fifty to a hundred feet long, and the maximum amount of pressure that can be withstood is about 1,204 psi. A normal sized man is about 154 pounds, and Bruce Willis, who is five feet and eleven inches, is closer to 195 pounds. If Willis was to jump off the side of a skyscraper, a massive amount of pressure would be forced upon the fire hose, causing it to break. Due to these technicalities, Bruce Willis would not be able to survive the jump. But, this still does not take into account the damage of the explosion. If Bruce Willis was miraculously able to survive the jump, the explosion would have caused severe burns and...
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...characteristics resemble those found in the myths we are studying. We would like to hear your thoughts on whether the stunt in question could be pulled off in real-life. In a scene from Die Hard, the main character, played by Bruce Willis, survives an explosion on the rooftop of a skyscraper by tying a fire hose to his waist, which breaks his fall, and allows him to smash a window of a lower story and take cover within the that story of the building. Willis falls 2-3 floors before the hose brings him to a complete stop. Now, as much as we love to witness the unlikely on a movie screen, we find it highly improbable that this could happen for a multitude of reasons. An average fire hose is about two and a half inches in diameter, anywhere from fifty to a hundred feet long, and the maximum amount of pressure that can be withstood is about 1,204 psi. A normal sized man is about 154 pounds, and Bruce Willis, who is five feet and eleven inches, is closer to 195 pounds. If Willis was to jump off the side of a skyscraper, a massive amount of pressure would be forced upon the fire hose, causing it to break. Due to these technicalities, Bruce Willis would not be able to survive the jump. But, this still does not take into account the damage of the explosion. If Bruce Willis was miraculously able to survive the jump, the explosion would have caused severe burns and...
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...Human Brain The anatomy of the brain is complex due its intricate structure and function. This amazing organ acts as a control center by receiving, interpreting, and directing sensory information throughout the body. There are three major divisions of the brain. They are the forebrain, the midbrain, and the hindbrain. Anatomy of the Brain: Brain Divisions The forebrain is responsible for a variety of functions including receiving and processing sensory information, thinking, perceiving, producing and understanding language, and controlling motor function. There are two major divisions of forebrain: the diencephalon and the telencephalon. The diencephalon contains structures such as the thalamus and hypothalamus which are responsible for such functions as motor control, relaying sensory information, and controlling autonomic functions. The telencephalon contains the largest part of the brain, the cerebral cortex. Most of the actual information processing in the brain takes place in the cerebral cortex. The midbrain and the hindbrain together make up the brainstem. The midbrain is the portion of the brainstem that connects the hindbrain and the forebrain. This region of the brain is involved in auditory and visual responses as well as motor function. The hindbrain extends from the spinal cord and is composed of the metencephalon and myelencephalon. The metencephalon contains structures such as the pons and cerebellum. These regions assists in maintaining balance...
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...movie that was selected to illustrate a high performance team in action was Armageddon which is directed by Michael Bay and stars Bruce Willis. Much of the material that we have studied illustrate that teams out perform individuals within an organization. This is most evident when performance requires multiple skills, judgments, and experiences (Katzenbach and Smith, 1993). In analyzing and comparing the characters and events in the movie, Armageddon, one sees many of the elements of a high performance team such as problem solving, goal setting, conflict resolution, and team dynamics. The traits of a leader were also visible through Bruce Willis’s character Harry Stamper. Hackman (2002) states that a leader must possess two critical skills; the first is skill in diagnosis and second skill in execution. Characteristics of a high performance team are evident throughout the movie. Armageddon is an action adventure film in which a meteor the size of Texas is careening towards the earth. NASA scientists discover it after a meteor shower destroys the Space Shuttle Atlantis, killing the entire crew. They only have 18 days before the asteroid destroys the earth. NASA devises a plan to insert a nuclear bomb 800 feet inside the asteroid, when detonated, will split the asteroid into two pieces that will safely fly past the Earth. Harry Stamper (Bruce Willis) is asked by NASA to help because he is considered the best deep sea oil driller in the world. After learning the details Harry tells...
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...Critique on Surrogates Robert Piccioli English 225 Brian Davis September 12, 2011 Critique on Surrogates The film Surrogates (2009), directed by Jonathon Mostow, was an excellent film with a powerful message for society. The message was delivered well through each aspect of the film and its elements. The film's main concept centers around the mysterious murder of a college student linked to the man who helped create a high-tech surrogate phenomenon that allows people to purchase remote controlled humanoid robots through which they interact with society. These fit, good-looking, remotely controlled robots ultimately assume their life roles, enabling people to experience life vicariously from the comfort and safety of their own homes. Online, you can hide behind an avatar and a lie of a profile and have complete anonymity. Expand that to real life, with a realistic looking robotic body, made in your own image, or not, and you have the world of "Surrogates." Most crime being a thing of the past, no more spreading diseases, racism and sexism gone and few, if any , consequences for your actions, (destroying a surrogate seems to be considered vandalism) all seem to take our own self centered, hedonistic, world of instant gratification to a whole new level. Throw in those who don't choose to keep them selves 'safe' by using robotic bodies living on reservations, seemingly shunning technology and being the subject of new racism, and you might think that you have a...
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...Mythological and Modern-Day Heroes Paper Over the years, there have been many heroes embarking upon quests, overcoming odds that are extraordinary for the common person and triumphing over evil. Each hero has shared many of the same characteristics as other heroes before him/her. From literature there are the tales of Odysseus, Beowulf and Sherlock Holmes. From popular culture, the tales of Harry Potter and Hogwart’s Castle, Frodo and Bilbo Baggins from the shire and Korben Dallas and Leeloo from the movie “Fifth Element”. Starring Bruce Willis (Korben Dallas), Milla Jovovich (Leeloo) and Gary Oldman (Jean-Baptiste Emanuel Zorg), the modern day hero complete with quest, lady fair and evil provides a pop culture version of the mythological hero and the mythological quest. Korben Dallas’ Hero’s Journey starts off as a regular joe taxi driver in the year 2263. Strong, compassionate, gruff, kind, skilled, intelligent and determined, Korben is the epitome of a hero. The strength of character, will and heart are characteristics shared by all heroes. The skills Korben possesses as well as the keen intellect, seen in his witty repartee, are true standards for a hero. His Achilles’ heel is the inability to express softer emotion. His one failing is not calling his mother. Korben Dallas exemplifies a mythological hero almost solely by his Heroic personality. Throughout the movie, the charisma and manly aura Dallas possesses in great quantities is exhibited by the hero with an...
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...Evan Brock 04/05/2013 Lester Young Lester Willis Young (August 27, 1909 – March 15, 1959), nicknamed "Pres" or "Prez", was an American jazz tenor saxophonist and clarinetist. He also played trumpet, violin, and drums. Coming to prominence while a member of Count Basie's orchestra, Young was one of the most influential players on his instrument. He played with a cool tone and used sophisticated harmonies, using "a free-floating style, wheeling and diving like a gull, banking with low, funky riffs that pleased dancers and listeners alike". Famous for his hip, introverted style, he invented or popularized much of the hipster ethos which came to be associated with the music. Lester Young was born in Woodville, Mississippi, and grew up in a musical family. His father, Willis Handy Young, was a respected teacher, his brother Lee Young was a drummer, and several other relatives played music professionally. His family moved to New Orleans, Louisiana, when Lester was an infant and later to Minneapolis, Minnesota. Although at a very young age Young did not initially know his father, he learned that his father was a musician. Later Willis taught his son to play the trumpet, violin, and drums in addition to the saxophone. Lester Young played in his family's band, known as the Young Family Band, in both the vaudeville and carnival circuits. He left the family band in 1927 at the age of 18 because he refused to tour in the Southern United States, where Jim Crow laws were in effect and racial...
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...Willis Pond History Compiled by Rob Hershfield, August 1999 From Reference Materials at Goodnow Library Geology and Geography The Cenozoic age began about six to eight million years ago, following the tropical Mesozoic age when dinosaurs and forests flourished. The Cenozoic has two main sub-divisions, the Tertiary and the Quaternary, the latter of which is again divided into three divisions: the Glacial, Champlain and Terrace. During the Glacial, an ice sheet reaching six thousand feet in thickness covered the entire northern portion of our continent including New England, and had a constant tendency to move south. During the Champlain Epoch, several small sheets of water such as Willis Pond, Bottomless Pond (now called Crystal Lake), Blandford’s Pond (on Cavicchio Farm – now filled in) and Pratt’s Pond (now Puffer Pond in the old Fort Devens Annex), were created in the Peakham area of Sudbury. These ponds probably owe their origin to large masses of ice having been left there, around which the sand was deposited by the currents, and later as these masses of ice melted they left the hollows which now hold the ponds. Willis Pond is the largest of these ponds and lies at the northwest part of town. It is nearly surrounded by forests, and is a little lake in the woods. It has an outlet to Hop Brook called Run Brook, which flows into the Sudbury River, the Concord, the Merrimack and into the Atlantic. The principal trees include White Pine, Oak, Maple, White...
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...Buy a temporarily discounted copy of Acousmatic Sorcery Buy tickets for the Principles of a Protagonist tour ABOUT To say that 27-year-old Willis Earl Beal has lived a colourful life would be a serious understatement. The Chicago native will tell you that his life has been one of "monotony" - which it has at times - but stints in the army, an ongoing desire to be a superhero, bouts of serious illness and a stretch of sleeping rough in an unfamiliar desert town would suggest otherwise. As an outsider artist, Beal's career always existed just beyond his imagination, with a history of leaving homemade novels, artwork and CD-Rs across America to promote his work, suggesting a desperate desire to be heard. This practice of "gifting" - matched with a natural booming voice, rich with range and a talent for penning raw, beautiful melodies - led to early features in both Found and the Chicago Reader that changed his life's course. Beal's creativity caught the attention of Hot Charity / XL Recordings who released Acousmatic Sorcery in March, 2012 - an 11 song set Beal wrote and recorded on a discarded karaoke machine while living in Albuquerque, NM. Since the release of Acousmatic Sorcery, Willis Earl Beal has toured the world, performing in clubs and festivals with nothing more than his guitar and back-up tape machine to support him. Delivering soul baring performances night after night, Beal has been lauded for not only his vocal mastery but the intensity with which he performs...
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...BEAUX ARTS A very rich, lavish and heavily ornamented classical style taught at L'Ecole des Beaux Arts in Paris in the 19th century The term "Beaux Arts" is the approximate English equivalent of "Fine Arts." The style was popularized during the 1893 Columbian Exposition in Chicago in 1893. One outgrowth of the Expo was the reform movement advocated by Daniel Burnham, the City Beautiful Movement. Very influential in the US in that many of the leading late 19th century architects had been trained at Ecole des Beaux Arts, e.g., Richard Morris Hunt (the first American to study there) , H. H. Richardson (the second American to study there, but who chose to develop his own style, "Richardsonian Romanesque") and Charles McKim, More than any other style (except perhaps the Chateauesque), the Beaux Arts expressed the taste and values of America's industrial barons at the turn of the century. In those pre-income tax days, great fortunes were proudly displayed in increasingly ornate and expensive houses. Broadly speaking, the term "Beaux Arts" refers to the American Renaissance period from about 1890 to 1920 and encompasses the French Renaissance, Italian Renaissance, and Neoclassical Revivals. In Buffalo, the movement was featured at the Pan-American Exposition in 1901. Features: * Symmetrical facade * Roofs: flat, low-pitched; mansard if modeled after French Renaissance Revival * Wall surfaces with decorative garlands, floral patterns, or cartouches dripping with...
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...Building the Burj Khalifa: Main: Chronological order 200 Mechanical, electrical and plumbing: air conditioning (temperature), 300 Safety – (getting everyone out) refuge rooms 300 Elevators– mention of transition from steam to motor and latched systems and electrical brakes and coping with load 100 Spire 100 Maintenance - Broadcast and communications floors, Mechanical Floors Conc: How it has progressed engineering and enabled more (buttress structure). Future plans – The kingdom Tower in Saudi (1km into the sky) Building potential: Space elevator, new arising problems, strength of materials, what that would mean and enable if possible. Throughout history, progression and advancement in technology has fundamentally separated us from our evolutionary antecedents, enabling a life of greater comfort, extravagance and an increased ability to procreate and sustain ourselves. This improvement is especially apparent in the world of architecture and civil engineering, where there has been an unremitting ambition to surpass the existing boundaries, particularly with regards to height. The most renowned early example of a structure where height was key are the Pyramids of Giza where elevation was crucial in order to radiate power and divine authority. The tallest pyramid, standing at 146.5m, was built more than 4500 years ago, and remained the tallest manmade structure for the next 3800 years, until the 1300s when Lincoln Cathedral was built topping it by only 13.5m [1][2]...
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