www.pwc.com/us/pharma Aspiring giants How small pharmas can drive to $1 billion — and beyond PwC’s PRTM Management Consulting Aspiring giants Executive summary Amid the volatile blend of opportunity and challenge that characterizes the global pharmaceutical industry, only a few small companies have managed to catapult their revenue over the $1 billion mark over the past two decades. Whether they chose to expand their therapeutic area focus and product portfolios, enter new geographies
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BY: Esa Girish Patel Student No: 104668544 Course: Biochem and Cell biology- Lipids & Membranes Instructor: Dr. Anna Kozarova INTRODUCTION: Ergosterol (ergosta-5, 7, 22-trien-3β-ol) is an isoprenoid compound (8) and a basic sterol found in cell membranes of fungi and protozoa that are considered as “Fungal sterol” (1). Ergosterol was discovered 125 years ago in plant pathogenic Ergot fungus Claviceps purpurea(1).Ergosterol is a characteristic component of the fungal cell membrane and is completely
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INTRODUCTION The rapid expansion and increasing sophistication of the chemical industries in the past century and particularly over the last thirty years has meant that there has been an increasing amount and complexity of toxic waste effluents. Even though policies and environmental efforts should continue to be directed towards applying pressure to industry to reduce toxic waste production, biotechnology presents opportunities to detoxify industrial effluents. Bacteria can be altered to produce
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Psych 100 Term Paper Psychological factors can be related to many different problems, one problem that had personally affected me was the grades I got my freshman year of college. I started my college career struggling a little bit and often wondered how I could raise my grades and improve my GPA until I was satisfied with the grades I would get. Coming to college I was finally on my own with no one to wake me up, make me do homework, or go to class. These all led to my GPA not being exactly
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Vyvanse: An Investigation of the New Breed of ADHD Treatment By Craig Leopold Psychopharmacology Dr. Zoladz 9 May 2011 On April 23, 2008, Vyvanse (lisdexamfetamine) received FDA approval for the adult population. The approval of this drug marked a new era in evolution of Attention Deficit Hyperactivity Disorder treatments. After decades of criticism on the rampant abuse and alleged overprescribing of amphetamine ADHD medications New River Pharmaceuticals responded by
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579 Atomic force microscopy and other scanning probe microscopies Helen G Hansma and Lía Pietrasanta The highlight of the past year is the unfolding and refolding of the muscle protein titin in the atomic force microscope. A related highlight in the intersection between experiment and theory is a recent review of the effects of molecular forces on biochemical kinetics. Other advances in scanning probe microscopy include entropic brushes, molecular sandwiches and applications of atomic force microscopy
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Neurodegenerative Disorders: Alzheimer’s Disease 1. Amyloid Precursor Protein (APP) Alzheimer’s disease (AD) remains a major cause of senile dementia, which is characterised by an impairment of neuronal and synaptic function in addition to the accumulation of β-amyloid plaque and formation of neurofibrillary tangles within distinct portions of the brain (De Strooper and Annaert, 2000). Progression of this distinct pathology of neurodegeneration does not typically vary from patient to patient
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| Cdx regulates Dll1 in Multiple Lineages | BIOL 303 Term Paper | | | BACKGROUND The vertebrate Cdx genes are a group of ParaHox genes that encode homeodomain transcription factors responsible for the anterior-posterior patterning of the embryonic axis, intestine, axial elongation and somitogenesis in mammals. These genes are related to Drosophila caudal (cad)[1] and there are three murine homologues Cdx1, Cdx2 and Cdx4 [2]. The Cdx gene products impact anterior-posterior vertebral
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Caffeine is the most-widely consumed psychoactive substance by human beings throughout the world (Reid, 2005). This report will detail its natural origins, chemical structure (as well as those of similar substances), and the methods and dosages in which it is rendered into its usable form. Additionally, this report will detail caffeine's various biological pathways within the human body, including access to the brain and various neurotransmitter pathways. Caffeine is a chemical
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[TITLE]* [Name of Student]* A thesis submitted to the Department of [Project dept]* National University of Singapore in partial fulfilment for the Degree of Bachelor of Science with Honours in Life Sciences *Please replace with the relevant inputs. Please delete this instruction in red. Cohort AY2012/2013 S1 GUIDELINES ON THESIS WRITING ( LSM4199 (Version V) Order of presentation The order of contents should be
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