ADAMTS-13 is a protease and it’s role is to cleave vWF (ulvWF). ADAMTS-13 INH ELISA allows us to detect the human autoantibodies (IgG) which is found in plasma and or serum against the ADAMTS-13. These autoantibodies inhibit ADAMTS-13 activity, hence non-cleaved ULvW gather in the plasma – one of the main causes of thrombotic thrombocytopenic purpura (TTP). TECHNOZYM® ADAMTS-13 INH test allows us to differentiate between autoantibodies (acquired) and congenital (gene polymorphisms) TTP when paired
Words: 345 - Pages: 2
ANSWER THE FOLLOWING QUESTIONS (ignore questions in lab manual) 1) Describe clearly and precisely the function of a positive control. 2) Describe the function of a negative control. What conclusions you would make about your entire experiment if the negative control did not act accordingly? 3) What might you conclude about the results of your test samples if one or more of the test samples tested positive but the positive control did not work according to plan? 4) What tubes represent the positive
Words: 590 - Pages: 3
Enzymes are proteins produced by a living organism, and act as efficient catalysts for specific chemical reactions. They are able to convert a specific set of reactants, known as substrates, into a specific set of products. Even at low temperatures, enzymes continue to allow a reaction to occur by lowering the activation energy of the given reaction. Reactions continue to occur even in the absence of enzymes, however due to the slow reaction rates without enzymes, sometimes the effects of the reaction
Words: 436 - Pages: 2
Introduction: This unit, about Enzymes and Biotechnology, contains information on how enzymes work in chemical reaction. For every enzyme there is a substrate made of reactant molecules that is worked upon. During a chemical reaction, the enzyme lactase breaks lactose molecules into their monomers, glucose and galactose. This lab is observing enzyme specificity as demonstrated by how lactase affects the presence of glucose in soy, cow, and rice milk. Data: Conclusion: 1. Cow milk contains lactose
Words: 283 - Pages: 2
honor code of University of the Pacific. (Please sign by typing your name or pasting an electronic signature if you have one) Signature: Jennae Fenton Date: 10/12/17 Abstract: The enzyme catechol oxidase is a protein that produces benzoquinone when the substrate catechol binds to the enzyme. This is commonly referred to as browning. How quickly produce spoils
Words: 1441 - Pages: 6
Background Dexcom is a medical device company based out of San Diego that uses innovative technology to improve the quality of life for diabetics across the globe. Dexcom is transforming diabetes management by providing superior continuous glucose (CGM) technology to help patients, and healthcare professionals better manage diabetes. Dexcom was founded in 1999, and went public in 2005. Kevin Sayer is the current CEO, and is on the board of directors with eleven others majority of whom have significant
Words: 1479 - Pages: 6
The first article discusses the gymnotiform fish Eigenmannia, a weakly electric fish, which generates a weakly electric signals for electrolocation and communication. Metzner provides explanation as to how the signals are produced and mentions the electric organ discharges (EODs) that are driven by a medullary pacemaker nucleus. The electrolocation can suffer from dramatic degradation when the conspecifics with a similar frequency are present in the environment. To avoid jamming, Eigenmannia modulates
Words: 688 - Pages: 3
In biology, in order to purify biological molecules, a common process called chromatography is often used. This process involves the separation of the large particles in the solution from the smaller particles. This is instrumental in filtering the solution, but without specialty scientific instruments, there is no way to immediately know the concentration of the, now separated, solution. However, there are multiple processes that are utilized to find unknown concentrations of a solution. One of
Words: 1684 - Pages: 7
Four cecally-cannulated horses were utilized in a 4 x 4 Latin square to evaluate dosage levels of LIPC on the same opportunistic bacteria stated in experiment 1 and to evaluate cecal characteristics. Horses were randomly assigned to one of four treatments: 1) no LIPC, (0); 2) 15 g of 500 mg/g of LIPC, recommended level (15); 3) 25 g of 500 mg/g of LIPC (25); or 4) 35 g of 500 mg/g of LIPC (35). Horses were fed 2-3 lbs of Strategy® (Purina Mills, St. Louis, MO), once a day at 0600 and treatment was
Words: 1871 - Pages: 8
is a non-essential amino acid that can be synthesized in the body through different metabolic pathways. Glutamate can be synthesized by two alternative routes which involve catalysis of GDH in the aminating direction, or via participation of two enzymes; glutamate synthethase (GS) and glutamate synthase or also termed glutamine oxoglutarate aminotransferase (GOGAT).
Words: 552 - Pages: 3
