Business Strategy and the Environment Bus. Strat. Env. (2009) Published online in Wiley InterScience (www.interscience.wiley.com) DOI: 10.1002/bse.657 Corporate Social Responsibility and Sustainability Reporting on the Internet J. Emil Morhardt* Roberts Environmental Center, Claremont McKenna College, Claremont, CA, USA ABSTRACT All material related to environmental and social performance on the corporate internet sites of 454 Fortune Global 500 and Fortune 1000 companies in 25 industrial
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Det moderne gennembrud En litterær revolution Mens verden moderniseres, hersker de nationalromantiske forestillinger fortsat. Æstetisk er de litterære idealer ude af trit med en moderne storbys puls. Georg Brandes (1842-1927) destruerer på kort tid det fundament, som den danske litteratur hviler på, og baner vejen for en tiltrængt modernisering. Den 3. november 1871 begynder Brandes en af sine forelæsninger over emnet: Hovedstrømninger i det nittende århundredes litteratur på Københavns
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Part Market-Driven Strategy 1 Chapter 1 Market-Driven Strategy The market and competitive challenges confronting executives around the world are complex and rapidly changing. Market and industry boundaries are often difficult to define because of the entry of new and unfamiliar forms of competition. Customers’ demands for superior value from the products they purchase are unprecedented, as they become yet more knowledgeable about products (goods and services) and more sophisticated
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TALAHANAYAN NG BUHAY, GINAWA, AT MGA SINULAT NI JOSE RIZAL KABANATA 1 - ANG PAGDATING NG PAMBANSANG BAYANI A. Pagsilang 1. Isinilang si Rizal Noong Hunyo 19, 1861 sa Calamba, Laguna 2. Bininyagan sa simbahan ng Calamba noong Hunyo 22, 1861. 3. Padre Rufino Collantes - paring nagbinyag kay Rizal 4. Padre Pedro Casanas - nagsilbing ninong ni Rizal A. Magulang 1. Francisco Mercado 1. Ipinanganak noong Mayo 11, 1818
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Belgium: Koen De Schrijver, Antwerp Bosnia and Herzogovina: Nina Rodić Vukmir, Banja Luka Bulgaria: Mira Kojouharova, Sofia Croatia: Sanja Musić Milanović, Zagreb Cyprus: to be nominated Czech Republic: Bohumir Križ, Prague Denmark: Peter Henrik Andersen, Copenhagen Senior editor Estonia: Kuulo Kutsar, Tallinn Kathrin Hagmaier Finland: Outi Lyytikäinen, Helsinki Scientific editors Karen Wilson Williamina Wilson France: Judith Benrekassa, Paris Germany: Jamela Seedat, Berlin
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jon24565_ch05.qxd 11/2/05 1:22 PM Page 138 C H A P T E R 5 Business Ethics and the Legal Environment of Business Learning Objectives After studying this chapter you should be able to: 1. Understand the relationship between ethics and the law and appreciate why it is important to behave ethically. 2. Differentiate between the claims of the different stakeholder groups affected by a company’s actions. 3. Identify the four main sources of business ethics, and describe
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Economic Consequences of the Sarbanes-Oxley Act of 2002 Ivy Xiying Zhang* William E. Simon Graduate School of Business Administration Carol Simon Hall 4-312 University of Rochester Rochester, NY 14627 zhangxi@simon.rochester.edu February 2005 I am grateful for the guidance of my dissertation committee, Bill Schwert, Charles Wasley, Ross Watts, and especially Jerry Zimmerman (Chairman). I also appreciate comments from Jim Brickley, Philip Joos, Andy Leone, Jerry Warner, Joanna Wu, Yan Cao, Ling
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1 Issues in Financial Reporting The path to knowledge cannot be found without visions and an overall picture. ± R. Mattessich oday's dynamic business environment is heralding a revolution in the need for, and the way in which, accounting data is utilized. This has resulted in talk of `an accounting revolution' (Beaver, 1998) and the possible `rede®nition of accountancy' (Elliott, 1998: 7). However, it is all too easy to become caught up in this stampede for change, but how far can accounting
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Global and Transnational Business: Strategy and Management Second Edition Global and Transnational Business: Strategy and Management Second Edition George Stonehouse Northumbria University David Campbell University of Newcastle-upon-Tyne Jim Hamill University of Strathclyde Tony Purdie Northumbria University Copyright # 2004 John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex PO19 8SQ, England Telephone (þ44) 1243 779777 Email (for orders and customer service
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能成为独立的泛素来源(Finley, 2009; Xu et al., 2009)。未连接的K48多泛素链对于蛋白酶体的亲和性从二聚体到四聚体增加了一百倍，四聚体以上亲和性骤减(Thrower et al., 2000)。 现在，很多实验表明实际上蛋白酶体会欣然接受其他类型的泛素链。间接证据就是特异的蛋白酶体阻遏不会导致只有K48多泛素链的聚集的结果。实际上，K63以外的所有链都增加了(Jacobson et al., 2009; Xu et al., 2009)。在细胞分裂中，人的APC/C募集两个E2连接酶，专有地结合并产生K11连接的泛素链(Song和Rape, 2010)。去除这个部分会导致降解程序失败，细胞可以观察到有丝分裂缺陷。体外实验表明K63修饰的二氢叶酸还原酶提供了一种高效的蛋白酶体底物(Hofmann和Pickart, 1999)。 图1、泛素是蛋白降解的一种常见标签 图2、主要降解途径的泛素识别 蛋白酶体由多蛋白裂解位点的核(20S)以及一个19S的调控部分组成。底物先被六聚ATP酶和调控部分展开以便进入蛋白酶体的核。调控部分的其他区域可能负责底物的募集(Finley
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