time after diagnosis), due to chemotherapeutic drug resistance from the tumor. Research has linked GBM to malfunction of the p53 tumor suppressing protein. When bound to overexpressed MDM2, an oncoprotein, p53 is inactivated and unable to inhibit cancer cell development, causing the tumor to grow and spread. This paper will analyze a research article by Costa et al. (2013) that focuses on using an inhibitor of MDM2 called ISA27 to increase p53 activity. The group hypothesized that applying the
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Proper oral health of those 65 and older is not being adequately met. Oral health is a key component in overall health. If care is not met, then it puts the patient at risk for diseases such as dental carries and gingivitis, which can affect his or her quality of life. Lack of oral hygiene also causes a decrease in self-esteem, social interaction, and dignity. It is therefore important that caregivers are provided the correct education, as well as the resources to implement oral hygiene practices
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involvement of the cecum in the inflammatory process, and isolated right-side colonic diverticular disease (rare) Special considerations: In order to plan an operation for a patient with colon cancer, the surgeon must have a thorough understanding of the tumor's location in the bowel, the stage of the cancer, and the patient's physiologic status. ( answer those with pt. info) Pharmacology: Preop- 4 L of polyethylene glycol solution is given to the patient to be taken over 2-3 hours in the afternoon
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stimulates cells to store nutrients to use between meals and at night to maintain blood glucose levels. Delta cells secrete somatostatin, after meals when blood glucose, fatty acids, and amino acids raise in the blood. Pancreatic cancer is a highly malignant cancer. Tumors commonly originate from the epithelial cells of the pancreatic ductal system. This can happen in two ways, one that it has metastasized from a different part of the body, generally the lungs, breast, thyroid, kidneys, and
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obvious causes of illness. Things such as a family history of illness, exposure to pathogens, gender, age, and the function of the immune system all play a part in a person’s health and well-being. A woman whose mother has been diagnosed with breast cancer has a greater chance of also being diagnosed as opposed to a woman who has no family history of the disease. A person who has been exposed to HIV is at a higher risk for developing AIDS than
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Cancer KEY POINTS Biology of Cancer Cancer encompasses a broad range of diseases of multiple causes that can arise in any cell of the body capable of evading regulatory controls of proliferation and differentiation. Two major dysfunctions present in the process of cancer are (1) defective cell proliferation (growth) and (2) defective cell differentiation. Cancer cells usually proliferate at the same rate of the normal cells of the tissue from which they arise. However, cancer cells divide
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complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy Alba Luengo1, Lucas B Sullivan1 and Matthew G Vander Heiden1,2* Abstract Metformin has been a first-line treatment for type II diabetes mellitus for decades and is the most widely prescribed antidiabetic drug. Retrospective studies have found that metformin treatment is associated with both reduced cancer diagnoses and cancer-related deaths. Despite the prevalence of metformin use in the clinic, its
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Services Part 1. Department of State Health Services Chapter 91. Cancer Subchapter A. Cancer Registry Effective Date: August 14, 2011 §91.1. Purpose. This subchapter implements the Texas Cancer Incidence Reporting Act, Health and Safety Code, Chapter 82. This legislation concerns the reporting of cases of cancer for the recognition, prevention, cure or control of those diseases, and to facilitate participation in the national program of cancer registries established by 42 United States Code, §§280e -
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Therefore, I will evaluate the article ‘Evaluation of a Belly Board immobilization device for rectal cancer patients receiving pre-operative chemoradiation’ by Gaya et al. (2014). The appraisal will not only show the strengths, but also the weaknesses in several parts of the article. Title The title of the article for appraisal is ‘Evaluation of a Belly Board immobilization device for rectal cancer patients receiving pre-operative chemoradiation’. This article was written by Gaya et al... The article
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other dermal pathologists worked on about 12 cases a week, Today the roster has grown to 7 dermal pathologists, and over 1500 cases a week. According to the BDL website, our 24-hour facility specializes in the diagnosis of skin, hair, nails, and the oral cavity. We have 30 employees, and 7 certified pathologists, who are very skilled and knowledgeable in dermal pathology. Our clients consist of over 50 physician offices, stretching from California to Washington, D.C.; who send us biopsy specimens in
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