However, during the course of your journey ideologies gradually change. Guevara, displaced and exploited Chilean Communist Peruvian Indians and found the remains of the Inca culture, the film shows that grow from the innocent but questioning the future Ernesto "Che", a leading Latin American peoples.

Although formed only a small part of the daily de Guevara, Granado Salles and believe it was witnessing the injustices in the leper colony of San Pablo Guevara made his biggest leap of faith. That way, patients were separated literally and symbolically of doctors, nurses and nuns by the treacherous Amazon River.

During the celebration of his birthday on the side of doctors, Guevara decide you'd rather spend your time with patients who had become so fond of and despite his severe asthma and protests about the dangers Granado-jumping and nothing to the other side. His journey metaphorically river marks a significant change in identity, the point at which you realize that what people need is not his scientific knowledge as a physician, but his desire for social change.

Other particularly poignant moments come when Guevara and Granado refuse to wear rubber gloves to treat people with leprosy because it means a hierarchical division among themselves;

At one point in the film, we see both Ernesto and Alberto meeting homeless communist couple is presented as a poor and struggling family. This scene is known as the "turning point" for Ernesto said "It was one p.m. colder but it made me closer to the human species," We learned that got forced out of their "hard, dry land "by property speculators and that the police wanted to arrest them because they are communists. Moreover, we also know that they plan to find a job in the mine, but in the end opted for the man but not the woman convey the idea of it being a "male" work

story of two friends brought together by their youthful restlessness, their desire and willingness to dream and their insatiable love for the road.

about youth, about the necessity of changing the world and believing that you can do so...it’s about idealism above anything else, and I think we live in an age where we tend to forget that idealism is necessary...the humanity, the appetite for life that was ingrained in this, in a very unfiltered, raw manner was tremendously attractive...

Appetite for life remains a constant theme throughout the film.

Eager to explore new things and meet new people, and with an open road—and an unknown world—in front of them, there is a sense of dreams and possibilities ahead. As they ride away on their motorcycle, they capture the spirit of the youth who search out a different future.

As they left behind the mines, Ernesto describes how he feels: "Al salir de las minas empezábamos a sentir que la realidad empezaba a cambiar, ¿o éramos nosotros?" "...encontrábamos mas indígenas que ni siquiera tenían un techo en donde fueron sus propias tierras...

"Los incas tenían un alto conocimiento en astronomía, medicina, matemáticas entre otras cosas. Pero los invasores tenían la pólvora." Later, the always-up-to-something Alberto shares his thoughts on change through the ballot box, to which Ernesto replies: "¿una revolución sin tiro? Estás loco."7

when Ernesto is on a steamboat on their way to the San Pablo leper colony in Peru. The steamboat is towing along a smaller segregated boat carrying the more impoverished sections of the people. He stares out into the smaller boat and feels the emotions stirring inside. No words are used in this scene—just striking images and penetrating music.

And there is an urgent question posing itself before Ernesto: on which side of the river is he going to spend all his life? Which side of the tracks?
Ernesto is challenged by all that he has seen. Throughout, he not only saw the poverty and the sickness but the humanity in the people he met along the way. He saw that the people are full of life, they have stories to tell, and they have knowledge and are resilient. He makes the decision to stand with them.