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Antipsychotics

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What is psychosis?

When someone experiences psychosis, they can lose contact with reality. Some of the symptoms include:
• Confused thinking; when everyday thoughts don’t seem to join up.
• Delusions; which are false beliefs that are not held by others from the same culture.
• Hallucinations; which is when a person hears, sees, or feels something that is not there. This is usually in the form of disembodied voices.

Psychosis can be brief, or it can be long standing when it’s associated with a longer term illness like schizophrenia.

How is psychosis treated?

The treatments available can reduce or sometimes eliminate the symptoms of psychosis. Ideally, treatment includes a combination of medications and community support programs. Antipsychotic medications restore the usual chemical balance in the brain; and community support programs help with practical things like getting information, finding work and securing accommodation.

How do antipsychotic medications work?

Inside the brain there are nerve cells called neurons. These neurons release chemicals, which transmit signals from one cell to the next. Antipsychotic medications mainly work by blocking a chemical called dopamine in the brain. Abnormally high levels of dopamine can cause the symptoms associated with schizophrenia and psychosis; such as delusions, hallucinations, paranoia and confused thinking.

What are the types of antipsychotics available?

Broadly speaking, there are two types of antipsychotics. They are the atypical (newer) antipsychotics and typical (older) antipsychotics. The main advantage of atypical antipsychotics is that there is less risk of developing ‘tardive dyskinesia’, a condition that causes one’s mouth, tongue and other parts of the body to move involuntarily. This condition is difficult to reverse. There are also fewer side effects like trembling or stiffening

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