1. Review the four principles of sex-linked inheritance listed just before the case study.
Which individuals in figure 5.2 demonstrate principle 1?
Terry, Greg, Jenny and Bill 2. Which individuals in figure 5.2 represent principle
2?
Greg, Carl and Terry

3. Which individuals in figure 5.2 represent principle
3?
Jessica, Terry, Florence and Greg

4. Why are none of the males in figure 5.2 shown as carriers of hemophilia?

If the male has an X, then he has the disease. A male can’t carry hemophilia due to them
Only having a single X chromosome and hemophilia is an X-linked disease.

5. What is the probability that Marcy and Tom will have any child with hemophilia (irrespective of sex)? Show how you calculate this.
The total probability would be 12.5%.
This is calculated by marcy having 50% chance of a carrier(0.5).Tom is not a carrier(0).
So the children would have a 25% chance which is 50% of Marcy’s 50%.(0.5).
Calculation is* (.5)(.5)(.5)=.125 =12.5%

6. Suppose Marcy becomes pregnant and has an amniocentesis, a prenatal cell-sampling technique that can identify the sex of a child (among other things). She finds that she is going to have a baby girl. Should she be worried that the baby will have hemophilia? Why or why not? Suppose she decides to be sterilized after her baby’s birth, so she will have only this one child. Should she be concerned that her grandchildren will have hemophilia? Why or why not?
I don’t think she should worry. She herself has a 50% of being a carrier and Tom is
Not a carrier. Therefore the chances of her daughter having hemophilia is low.

7. Blood typing can help determine paternity.
Suppose an unmarried woman gives birth, charges a certain man with being the father, and sues for child support. He demands blood tests, which show that the woman is type A, the baby is type
A, and he is type B. Does this evidence rule him out as the father? Explain why or why not.

8. The drugs for cancer chemotherapy target rapidly dividing tumor cells, but also any other cells in the body that undergo rapid mitosis. In light of this, explain why these drugs often cause hair loss as a side effect.

9. Based on the data in table 5.1, which type of cancer—colon or oral—do you think is more treatable (has the better prognosis)? Explain your reasoning.