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Cancer Treatments

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Submitted By bunny12
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Week 5 Assignment 2.1 Submission

The Public Needs to Know-Revised Version

Georgia Reaves

English Composition
Maureen O'Bier
November 10, 2013

As you're reading this, you can probably think of a few people you know personally that have battled cancer or are battling it right now. Do you ever think about the drugs that it takes to keep them healthy or how their produced? It's a long process, but it is most certainly worth the wait. These drugs save lives.

Approximately 7.6 million people die from cancer each year and most of these deaths can be prevented. Drugs like Herceptin(breast cancer) and Methotrexate(lung cancer) are tested to prevent deaths that can be avoided all together. There are several different types of cancer, which means there is a demand for several different drugs to fight each type of cancer. These drugs are needed to keep the patients healthy. The treatments are needed to take cancerous cells out of the body and to also make sure the cancer won't come back. The fact that these deaths can be avoided is all the more reason to keep producing new drugs.

The FDA, also known as the U.S. Food and Drug Administration are responsible for making sure all drugs are effective and safe before they are able to go on the market. The public's health and speeding up the testing process to make medicine more affordable, effective and safer is their job. The FDA's main goal is to maintain the public's health by regulating the food and drugs that are given out to the public. Drugs that are available to the public are always tested for quality purposes. The FDA has many tasks, from testing the drugs multiple times, to making them affordable and making the labels and amounts accurate. This is what the U.S. Food and Drug Administration is responsible for.

The process the FDA goes through is tedious, but only to insure the safety of patients that will possibly use the drugs. It takes about twelve years for a new drug to go from the laboratory to the pharmacy shelf. “Only one in 1000 of the compounds that enter laboratory testing will ever make it to the human testing.” said by Drugs.com. Before an application can be made to the U.S. Food and Drug Administration, a drug typically undergoes around three years of testing. If the FDA gives the green light to “investigate”, the drug will go through three different phases. Phase one can use twenty to eighty healthy volunteers to make sure the drug is safe. This takes approximately one year. The second phase employs one hundred to three hundred people to test the drugs effectiveness. This takes about two years. The third phase involves one thousand to three thousand patients in hospitals and clinics who are monitored often to determine the effectiveness and determine if there are any side effects. This phase can take up to three years. After these three phases the company submits an application to the FDA, which is around 100,000 pages. This can take up to two and a half years. After the final approval, the drug becomes available for physicians to subscribe to patients. While the drug has been approved, it is still being watched closely. Any adverse reactions are reported. It is obvious the drug testing process it lengthy.

When it comes to testing a drug for cancer patients, most drugs that are being developed start from studying the biology of cancer cells. Most researchers start off by comparing genetics(DNA) and cellular processes of cancer cells to healthy cells. This allows researchers to identify important steps in the cancer development process and allows them to potentially alter this by using a drug. Once potential drugs are identified, they are tested in human tumor cells to see if they can stop the growth of cancer cells. The drug is next tested in animals to be sure that it is effective. The drugs can be tested on two or more different species of animals. Testing on animals helps researchers identify how the drug affects the body, what dosages can be used and the side effects the drug could potentially cause. This is the effective way to test drugs.

Since some drugs are tested on animals to make sure they are effective and safe, this can be considered an economic issue. If animals are being tested on and it is not certain that the drugs will not hurt them, then this can be a problem. Some animals might not react well to the drugs, which can cause health issues and even death. This would lead to too many animals being affected by drug testing. Drugs are tested on the animals before patients to insure no humans will risk their lives, but this process can possibly hurt animals.

There is something called In Vitro Testing, which is also known as “test tube experiments”. This is a controlled experiment. In Vivo testing, which is the opposite of In Vitro testing is an experiment using a whole living organism. In Vivo is related to animal testing. The In Vivo testing method is used to test most of the drugs for cancer. As you can see in the chart below, In Vivo is the more predictable source, but it is also expensive and time consuming.

Cancer patients have many different special needs. No one should be forced to face cancer alone. Family members, support groups, other cancer patients, doctors and nurses can help patients out during this difficult time. Family members can help with rides to doctors appointments, meals, and even lending a listening ear. Support groups can help to make the patient feel like they are not alone and everyone in the group can lift each other up. Other cancer patients can inform new cancer patients on what to expect and can also give hope for the future. Doctors help to inform patients if they are getting better or worse, decide what treatments you need, and help you get support. These are all needs of the average cancer patient. All of these people play huge roles when it comes to helping a cancer patient's needs.

It is very clear that cancer takes too many lives a year. We need the proper drugs and treatments to prevent these deaths. A cure for cancer would be life changing, but until then we must depend on different drugs to help these patients. These patients can't just use any drugs. That's why drugs are thoroughly tested.

Cancer is not going away. It is an illness that attacks millions of people a year. Since there is no cure, doctors must treat this illness and subscribe the proper drugs needed. To do this, drugs go through the process of being tested. The many drugs used help make it easier for cancer patients. There are so many people dealing with cancer, so these drugs help them live a normal life. This program simply saves many lives.

So now that you know the process of testing drugs for cancer patients and how it benefits them, you are able to understand how important this process is to our nation. There are so many people battling cancer, and it is comforting to know there are people out there making it easier for them to survive.
References:
http://www.cancer.net/all-about-cancer/cancernet-feature-articles/cancer-basics/drug-discovery-development http://www.cancer.gov/clinicaltrials/learningabout/approval-process-for-cancer-drugs/page4 http://www.drugs.com/fda-approval-process.html http://www.cancer.gov/cancertopics/takingtime/page6

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