...This is due to spontaneous mutation in the gene during reproduction.1 Genomic DNA from peripheral leukocytes can be screened using conformation-sensitive gel electrophoresis (CSGE) and single-strand conformation polymorphism (SSCP).8 Mutation screening of the FBN1 genomic sequences was performed by augmentation of 65 fragments.8 These methods has proven success for better diagnosis for patients suffering from Marfan syndrome. Although there is some diagnostic measure that can be done, an overall understanding is still lacking for better...
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